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  2. DXO - decapping exoribonuclease Gene

DXO - decapping exoribonuclease Gene

Homo sapiens

Also known as NG6; RAI1; DOM3L; DOM3Z

Gene ID: 1797 | Gene type: protein coding

About DXO

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,969,815-31,972,138 (from NCBI)

This gene has 15 transcripts (splice variants), 1 gene allele and 202 orthologues. Ubiquitous expression in testis (RPKM 17.8), adrenal (RPKM 16.9) and 25 other tissues.

Summary

This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. The function of its protein product is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that this may be a housekeeping gene. [provided by RefSeq, Jul 2008]

DXO Products(3)

mRNA Protein Name
NM_001371205.1 NP_001358134.1 decapping and exoribonuclease protein isoform 1
NM_001371206.1 NP_001358135.1 decapping and exoribonuclease protein isoform 1
NM_005510.4 NP_005501.2 decapping and exoribonuclease protein isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
Biological Process GO Annotation Evidence Reference Source
involved in NAD-cap decapping IDA
IDA: Inferred from direct assay
28283058 GOA
involved in mRNA catabolic process IDA
IDA: Inferred from direct assay
29601584 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
29601584 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DXO Protein Structure

RAI1

RAI1: RAI1 like PD-(D/E)XK nuclease (235 - 302)

  • 0
  • 100
  • 200
  • 300
  • 396 a.a.
Protein Preferred Names Protein Names

decapping and exoribonuclease protein

5'-3' exoribonuclease DXO

DXO Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra DXO O77932 FKBP1A Homo sapiens Q0VDC6
Validated Y2H
32814053
Intra DXO O77932 FKBP1A Homo sapiens Q0VDC6
Y2H Array
32814053
Intra DXO O77932 FKBP1A Homo sapiens Q0VDC6
Y2H Pooling
32814053
Intra DXO O77932 SARS1 Homo sapiens P49591
Y2H Array
32814053
Intra DXO O77932 SARS1 Homo sapiens P49591
Y2H Pooling
32814053
Intra DXO O77932 SARS1 Homo sapiens P49591
Validated Y2H
32814053
Intra DXO O77932 EIF2S3 Homo sapiens P41091
Validated Y2H
32814053
Intra DXO O77932 EIF2S3 Homo sapiens P41091
Y2H Array
32814053
Intra DXO O77932 EIF2S3 Homo sapiens P41091
Y2H Pooling
32814053
Intra DXO O77932 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra DXO O77932 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra DXO O77932 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra DXO O77932 BAG6 Homo sapiens P46379-2
Validated Y2H
32814053
Intra DXO O77932 BAG6 Homo sapiens P46379-2
Y2H Array
32814053
Intra DXO O77932 BAG6 Homo sapiens P46379-2
Y2H Pooling
32814053
Intra DXO O77932 ERN1 Homo sapiens O75460-2
Validated Y2H
32814053
Intra DXO O77932 ERN1 Homo sapiens O75460-2
Y2H Pooling
32814053
Intra DXO O77932 ERN1 Homo sapiens O75460-2
Y2H Array
32814053
Intra DXO O77932 HSPB1 Homo sapiens P04792
Validated Y2H
32814053
Intra DXO O77932 HSPB1 Homo sapiens P04792
Y2H Pooling
32814053
Intra DXO O77932 HSPB1 Homo sapiens P04792
Y2H Array
32814053
Intra DXO O77932 VIM Homo sapiens P08670
Validated Y2H
32814053
Intra DXO O77932 VIM Homo sapiens P08670
Y2H Array
32814053
Intra DXO O77932 VIM Homo sapiens P08670
Y2H Pooling
32814053
Intra DXO O77932 CCT7 Homo sapiens Q99832
Y2H Array
32814053
Intra DXO O77932 CCT7 Homo sapiens Q99832
Y2H Pooling
32814053
Intra DXO O77932 CCT7 Homo sapiens Q99832
Validated Y2H
32814053
Intra DXO O77932 RNF11 Homo sapiens Q9Y3C5
Y2H Pooling
32814053
Intra DXO O77932 RNF11 Homo sapiens Q9Y3C5
Validated Y2H
32814053
Intra DXO O77932 RNF11 Homo sapiens Q9Y3C5
Y2H Array
32814053
Intra DXO O77932 PECAM1 Homo sapiens P16284
Validated Y2H
32814053
Intra DXO O77932 PECAM1 Homo sapiens P16284
Y2H Array
32814053
Intra DXO O77932 PECAM1 Homo sapiens P16284
Y2H Pooling
32814053
Intra DXO O77932 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra DXO O77932 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra DXO O77932 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra DXO O77932 PRPS1 Homo sapiens P60891
Validated Y2H
32814053
Intra DXO O77932 PRPS1 Homo sapiens P60891
Y2H Array
32814053
Intra DXO O77932 PRPS1 Homo sapiens P60891
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DXO RGD RGD:1303267
Bos taurus DXO VGNC VGNC:50147
Macaca mulatta DXO VGNC VGNC:71970
Mus musculus DXO MGD MGI:1890444
Felis catus DXO VGNC VGNC:61673
Canis familiaris DXO VGNC VGNC:40140