Rcor1 - REST corepressor 1 Gene

Mus musculus

Also known as Rocr1; D12Wsu95e; mKIAA0071; 5730409O11; 6720480E22Rik

Gene ID: 217864 | Gene type: protein coding

About Rcor1

Summary

Enables chromatin binding activity and Enzyme binding activity. Involved in erythrocyte differentiation; negative regulation of gene expression; and positive regulation of megakaryocyte differentiation. Predicted to be located in nucleoplasm. Predicted to be part of DNA repair complex; histone deacetylase complex; and transcription repressor complex. Is expressed in brain; early embryo; extraembryonic component; and nose. Orthologous to human RCOR1 (REST corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Rcor1 Products(1)

mRNA	Protein	Name
NM_198023.3	NP_932140.2	REST corepressor 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	17392792	MGI
enables enzyme binding	IPI IPI: Inferred from physical interaction	24843136	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	15907476	MGI
enables transcription corepressor activity	IDA IDA: Inferred from direct assay	17707228	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within erythrocyte differentiation	IMP IMP: Inferred from mutant phenotype	24652990	MGI
involved in erythrocyte differentiation	IMP IMP: Inferred from mutant phenotype	17707228	MGI
involved in negative regulation of gene expression	IDA IDA: Inferred from direct assay	15907476	MGI
involved in positive regulation of megakaryocyte differentiation	IMP IMP: Inferred from mutant phenotype	17707228	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

REST corepressor 1

Rcor1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Rcor1	Q8CFE3	Kdm1a	Mus musculus	Q6ZQ88	Anti Bait CoIP	22297846
Intra	Rcor1	Q8CFE3	Nr4a2	Mus musculus	Q06219	Anti Bait CoIP	19345186
Intra	Rcor1	Q8CFE3	Nr4a2	Mus musculus	Q06219	Pull Down	19345186
Intra	Rcor1	Q8CFE3	Nr4a2	Mus musculus	Q06219	Anti Tag CoIP	19345186

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11791	RCOR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rcor1	NCBI	NCBI:23186

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