2. Gene
  3. Tfpi - tissue factor pathway inhibitor Gene

Tfpi - tissue factor pathway inhibitor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EPI; LACI; A630013F22Rik

Gene ID: 21788 | Gene type: protein coding

About Tfpi

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of blood coagulation. Predicted to act upstream of or within blood coagulation. Located in extracellular space. Is expressed in several structures, including central nervous system; hemolymphoid system; liver; lung; and retina. Human ortholog(s) of this gene implicated in several diseases, including Factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Orthologous to human TFPI (tissue factor pathway inhibitor). [provided by Alliance of Genome Resources, Apr 2022]

Tfpi Products(5)

mRNA Protein Name
NM_001177319.1 NP_001170790.1 tissue factor pathway inhibitor isoform b precursor
NM_001177320.1 NP_001170791.1 tissue factor pathway inhibitor isoform b precursor
NM_001355271.1 NP_001342200.1 tissue factor pathway inhibitor isoform a precursor
NM_001355273.1 NP_001342202.1 tissue factor pathway inhibitor isoform a precursor
NM_011576.1 NP_035706.1 tissue factor pathway inhibitor isoform a precursor
Protein Preferred Names Protein Names

tissue factor pathway inhibitor

extrinsic pathway inhibitor

lipoprotein-associated coagulation inhibitor

Recombinant Tfpi Proteins

Cat. No. Product Name Accession Purity
HY-P73425 TFPI Protein, Mouse (HEK293, His) NP_035706.1 (L29-K289) ≥95%
HY-P73425A TFPI Protein, Mouse (HEK293, C-His) O54819-1 (L29-K289) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-153480 ARC19499 Inhibitor 93.65% Phase 1
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P99725 Marstacimab 96.27% Phase 3
HY-P99283 Concizumab 95.00% Phase 3
HY-P99465 Befovacimab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153480A ARC19499 sodium Inhibitor 93.65% Unkown
HY-RS14427 TFPI Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14428 TFPI2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tfpi NCBI NCBI:7035
Leporidae Tfpi NCBI