1. Gene
  2. TNRC6B - trinucleotide repeat containing adaptor 6B Gene

TNRC6B - trinucleotide repeat containing adaptor 6B Gene

Homo sapiens

Also known as GDSBA

Gene ID: 23112 | Gene type: protein coding

About TNRC6B

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:40,044,834-40,335,808 (from NCBI)

This gene has 9 transcripts (splice variants), 293 orthologues, 5 paralogues and is associated with 3 phenotypes. Ubiquitous expression in testis (RPKM 3.9), thyroid (RPKM 2.3) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in regulation of gene expression. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. Implicated in subserous uterine fibroid and uterine fibroid. [provided by Alliance of Genome Resources, Apr 2022]

TNRC6B Products(3)

mRNA Protein Name
NM_001024843.2 NP_001020014.1 trinucleotide repeat-containing gene 6B protein isoform 3
NM_001162501.2 NP_001155973.1 trinucleotide repeat-containing gene 6B protein isoform 1
NM_015088.3 NP_055903.2 trinucleotide repeat-containing gene 6B protein isoform 2

TNRC6B Protein Structure

Ago_hook

Ago_hook: Argonaute hook (940 - 1061)

RRM_5

RRM_5: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (1664 - 1718)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1833 a.a.
Protein Preferred Names Protein Names

trinucleotide repeat-containing gene 6B protein

trinucleotide repeat containing 6B

Related Diseases

Diseases Alias
Global Developmental Delay With Speech And Behavioral Abnormalities

GDSBA

Non-Specific Syndromic Intellectual Disability

Complex Neurodevelopmental Disorder

Subserous Uterine Fibroid

Subserous Leiomyoma Of Uterus

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Rectum Adenocarcinoma

Rectal Adenocarcinoma

Adenocarcinoma Of Rectum

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

Coffin-Siris Syndrome 1

Coffin-Siris Syndrome

Fifth Digit Syndrome

Css

CSS1

Mrd12

Mental Retardation, Autosomal Dominant 12

Hhid

Dwarfism-Onychodysplasia

Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features

Autosomal Dominant Mental Retardation 12

Short Stature-Onychodysplasia.

Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx

Mental Retardation With Hypoplastic Fifth Fingernails And Toenails

Short Stature-Onychodysplasia

Coffin-Siris Syndrome, Type 1

Mental Retardation, Autosomal Dominant, Type 12

Strabismus

Strabismus, Susceptibility To

Strabismus, Susceptibility To, 1

Strabismus 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus TNRC6B VGNC VGNC:36205
Macaca mulatta TNRC6B VGNC VGNC:79786
Felis catus TNRC6B VGNC VGNC:66434
Rattus norvegicus TNRC6B RGD RGD:621428
Canis familiaris TNRC6B VGNC VGNC:82302
Mus musculus TNRC6B MGD MGI:2443730