2. Gene
  3. METAP1 - methionyl aminopeptidase 1 Gene

METAP1 - methionyl aminopeptidase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MAP1A; MetAP1A

Gene ID: 23173 | Gene type: protein coding

About METAP1

Cytogenetic location: 4q23 Genomic coordinates (GRCh38): 4:98,995,721-99,062,809 (from NCBI)

This gene has 12 transcripts (splice variants), 211 orthologues and 7 paralogues. Ubiquitous expression in esophagus (RPKM 20.9), testis (RPKM 19.8) and 25 other tissues.

Summary

Predicted to enable Aminopeptidase activity and metalloexopeptidase activity. Involved in platelet aggregation. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

METAP1 Products(1)

mRNA Protein Name
NM_015143.3 NP_055958.2 methionine aminopeptidase 1

METAP1 Protein Structure

Peptidase_M24

Peptidase_M24: Metallopeptidase family M24 (137 - 365)

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  • 386 a.a.
Protein Preferred Names Protein Names

methionine aminopeptidase 1

MAP 1

Recombinant METAP1 Proteins

Cat. No. Product Name Accession Purity
HY-P70380 METAP1/Methionine aminopeptidase 1 Protein, Human P53582 (M1-F386) ≥95%

Related Diseases

Diseases Alias
Microsporidiosis

Infection By Microspora

Microsporidiasis

Infection By Microsporea

Infection By Microsporida

Intestinal Microsporidiosis

Microsporidia Infection

Infection By Microsporidia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-133016 M8891 Inhibitor 98.97% Phase 1
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-143249 MtMetAP1-IN-1 Inhibitor / Unkown
HY-RS08348 METAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08349 METAP1D Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W282615 Antibacterial agent 117 98.01% Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus METAP1 MGD MGI:1922874
Felis catus METAP1 VGNC VGNC:63454
Macaca mulatta METAP1 VGNC VGNC:74514
Rattus norvegicus METAP1 RGD RGD:1305545
Canis familiaris METAP1 VGNC VGNC:43167
Bos taurus METAP1 VGNC VGNC:31395
Others METAP1 NCBI