CSTF2T - cleavage stimulation factor subunit 2 tau variant Gene

Homo sapiens

Also known as CstF-64T

Gene ID: 23283 | Gene type: protein coding

About CSTF2T

Cytogenetic location: 10q21.1 Genomic coordinates (GRCh38): 10:51,695,486-51,699,595 (from NCBI)

This gene has 1 transcript (splice variant), 106 orthologues and 5 paralogues.

Summary

Enables RNA binding activity. Predicted to be involved in pre-mRNA cleavage required for polyadenylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CSTF2T Products(1)

mRNA	Protein	Name
NM_015235.3	NP_056050.1	cleavage stimulation factor subunit 2 tau variant

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CSTF2T Protein Structure

RRM_1

CSTF2_hinge

CSTF_C

0
100
200
300
400
500
616 a.a.

Protein Preferred Names

Protein Names

cleavage stimulation factor subunit 2 tau variant

CF-1 64 kDa subunit tau

CSTF2T Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CSTF2T	Q9H0L4	TLE5	Homo sapiens	Q08117-2	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	TLE5	Homo sapiens	Q08117-2	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	CTAG1A	Homo sapiens	P78358	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	CTAG1A	Homo sapiens	P78358	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	SPAG8	Homo sapiens	Q99932-2	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	SPAG8	Homo sapiens	Q99932-2	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	FOXI1	Homo sapiens	Q12951-2	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	FOXI1	Homo sapiens	Q12951-2	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	FAM168B	Homo sapiens	A1KXE4-2	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	FAM168B	Homo sapiens	A1KXE4-2	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	ATP23	Homo sapiens	Q9Y6H3	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	ATP23	Homo sapiens	Q9Y6H3	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	ATP23	Homo sapiens	Q9Y6H3	Validated Y2H	32296183
Intra	CSTF2T	Q9H0L4	TOX2	Homo sapiens	Q96NM4-3	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	TOX2	Homo sapiens	Q96NM4-3	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	STH	Homo sapiens	Q8IWL8	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	STH	Homo sapiens	Q8IWL8	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	a0a1u9x8x8_human	Homo sapiens	A0A1U9X8X8	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	a0a1u9x8x8_human	Homo sapiens	A0A1U9X8X8	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	COL17A1	Homo sapiens	Q9UMD9	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	COL17A1	Homo sapiens	Q9UMD9	Validated Y2H	32296183
Intra	CSTF2T	Q9H0L4	COL17A1	Homo sapiens	Q9UMD9	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	PKNOX2	Homo sapiens	Q96KN3	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	PKNOX2	Homo sapiens	Q96KN3	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	FOXJ2	Homo sapiens	Q9P0K8	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	FOXJ2	Homo sapiens	Q9P0K8	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	SMYD3	Homo sapiens	Q9H7B4	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	SMYD3	Homo sapiens	Q9H7B4	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	SMYD3	Homo sapiens	Q9H7B4	Validated Y2H	32296183
Intra	CSTF2T	Q9H0L4	AKAP8L	Homo sapiens	Q9ULX6	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	AKAP8L	Homo sapiens	Q9ULX6	Validated Y2H	32296183
Intra	CSTF2T	Q9H0L4	AKAP8L	Homo sapiens	Q9ULX6	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	HGS	Homo sapiens	O14964	Y2H Prey Pooling	25416956
Intra	CSTF2T	Q9H0L4	HGS	Homo sapiens	O14964	Validated Y2H	25416956
Intra	CSTF2T	Q9H0L4	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	25416956
Intra	CSTF2T	Q9H0L4	UBQLN1	Homo sapiens	Q9UMX0	Y2H Pooling	16189514
Intra	CSTF2T	Q9H0L4	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32296183
Intra	CSTF2T	Q9H0L4	UBQLN1	Homo sapiens	Q9UMX0	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	CTDSP1	Homo sapiens	Q9GZU7	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	CTDSP1	Homo sapiens	Q9GZU7	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	LASP1	Homo sapiens	Q14847-2	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	LASP1	Homo sapiens	Q14847-2	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	CSTF2T	Q9H0L4	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	CSTF2T	Q9H0L4	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Oligoasthenoteratozoospermia

Oat	Oligoasthenoteratospermia

Oculopharyngeal Muscular Dystrophy

OPMD	Muscular Dystrophy, Oculopharyngeal
Dystrophy, Oculopharyngeal Muscular	Oculopharyngeal Dystrophy
Progressive Muscular Dystrophy, Oculopharyngeal Type	Muscular Dystrophy Oculopharyngeal
Dystrophy, Muscular, Oculopharyngeal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03275	CSTF2T Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CSTF2T	MGD	MGI:1932622
Rattus norvegicus	CSTF2T	RGD	RGD:1310026
Macaca mulatta	CSTF2T	VGNC	VGNC:106027
Bos taurus	CSTF2T	VGNC	VGNC:27782

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