SULT4A1 - sulfotransferase family 4A member 1 Gene

Homo sapiens

Also known as NST; BRSTL1; SULTX3; BR-STL-1; DJ388M5.3; hBR-STL-1

Gene ID: 25830 | Gene type: protein coding

About SULT4A1

Cytogenetic location: 22q13.31 Genomic coordinates (GRCh38): 22:43,824,509-43,862,513 (from NCBI)

This gene has 4 transcripts (splice variants), 243 orthologues and 12 paralogues. Biased expression in brain (RPKM 30.9), duodenum (RPKM 4.1) and 2 other tissues.

Summary

This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. [provided by RefSeq, Jul 2008]

SULT4A1 Products(1)

mRNA	Protein	Name
NM_014351.4	NP_055166.1	sulfotransferase 4A1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IDA IDA: Inferred from direct assay	32152050	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	19439498	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	19439498	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SULT4A1 Protein Structure

Sulfotransfer_1

0
100
200
284 a.a.

Protein Preferred Names

Protein Names

sulfotransferase 4A1

ST4A1

Recombinant SULT4A1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71344	SULT4A1 Protein, Human	Q9BR01 (M1-L284)	≥95%

Related Diseases

Diseases

Alias

Anteroseptal Myocardial Infarction

Mixed Receptive-Expressive Language Disorder

Mitochondrial Dna Depletion Syndrome 1

MTDPS1	Mitochondrial Neurogastrointestinal Encephalopathy Syndrome, Tymp-Related
Myoneurogastrointestinal Encephalopathy Syndrome	Polip Syndrome
Mitochondrial Dna Depletion Syndrome, Type 1	Mngie, Tymp-Related
Polyneuropathy, Ophthalmoplegia, Leukoencephalopathy, And Intestinal Pseudoobstruction	Mitochondrial Dna Depletion Syndrome 1, Mngie Type
Mitochondrial Neurogastrointestinal Encephalomyopathy	Mitochondrial Neurogastrointestinal Encephalopathy Syndrome Tymp-Related
Myoneurogastrointestinal Encephalomyopathy	Polyneuropathy Ophthalmoplegia Leukoencephalopathy And Intestinal Pseudoobstruction
Mitochondrial Neurogastrointestinal Encephalopathy Syndrome

Neuronitis

Cercarial Dermatitis

Swimmer'S Itch	Cutaneous Schistosomiasis
Sea Bather'S Eruption	Clam-Digger'S Itch
Rice-Paddy Itch	Sea Bather'S Itch
Sawah Itch	Schistosomal Cercarial Dermatitis

N Syndrome

NSX	Intellectual Disability, Malformations, Chromosome Breakage, And Development Of T-Cell Leukemia

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Inferior Myocardial Infarction

Inferior Wall Myocardial Infarction

Schizotypal Personality Disorder

Schizotypal Personality

Phelan-Mcdermid Syndrome

Chromosome 22q13.3 Deletion Syndrome	22q13.3 Deletion Syndrome
Telomeric 22q13 Monosomy Syndrome	PHMDS
Deletion 22q13 Syndrome	22q13.3 Deletion
Deletion 22q13.3 Syndrome	Monosomy 22q13
Monosomy 22q13.3	22q13 Deletion Syndrome
Monosomy 22q13 Syndrome	22q13 Deletion
Chromosome Deletion

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14022	SULT4A1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SULT4A1	VGNC	VGNC:78119
Rattus norvegicus	SULT4A1	RGD	RGD:69292
Canis familiaris	SULT4A1	VGNC	VGNC:46980
Mus musculus	SULT4A1	MGD	MGI:1888971
Felis catus	SULT4A1	VGNC	VGNC:65838
Bos taurus	SULT4A1	VGNC	VGNC:35469
Others	SULT4A1	NCBI

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