PARVG - parvin gamma Gene

Homo sapiens

Gene ID: 64098 | Gene type: protein coding

About PARVG

Cytogenetic location: 22q13.31 Genomic coordinates (GRCh38): 22:44,172,951-44,208,469 (from NCBI)

This gene has 12 transcripts (splice variants), 193 orthologues and 2 paralogues. Broad expression in spleen (RPKM 17.3), bone marrow (RPKM 16.9) and 19 other tissues.

Summary

Members of the parvin family, including PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM, Aug 2004]

PARVG Products(2)

mRNA	Protein	Name
NM_001137605.3	NP_001131077.1	gamma-parvin
NM_022141.7	NP_071424.1	gamma-parvin

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PARVG Protein Structure

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

gamma-parvin

PARVG Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PARVG	Q9HBI0	TSGA10IP	Homo sapiens	Q3SY00	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	TSGA10IP	Homo sapiens	Q3SY00	Y2H Array	32296183
Intra	PARVG	Q9HBI0	KLHL32	Homo sapiens	Q5THT1	Validated Y2H	25416956
Intra	PARVG	Q9HBI0	KLHL32	Homo sapiens	Q5THT1	Y2H Array	25416956
Intra	PARVG	Q9HBI0	KLHL32	Homo sapiens	Q5THT1	Y2H Prey Pooling	25416956
Intra	PARVG	Q9HBI0	REL	Homo sapiens	Q04864-2	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	REL	Homo sapiens	Q04864-2	Y2H Array	32296183
Intra	PARVG	Q9HBI0	ALX4	Homo sapiens	Q9H161	Y2H Array	32296183
Intra	PARVG	Q9HBI0	ALX4	Homo sapiens	Q9H161	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	TLE5	Homo sapiens	Q08117-2	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	TLE5	Homo sapiens	Q08117-2	BFG-2H	27107012
Intra	PARVG	Q9HBI0	TLE5	Homo sapiens	Q08117-2	Y2H Array	32296183
Intra	PARVG	Q9HBI0	KCTD7	Homo sapiens	Q96MP8-2	Y2H Array	32296183
Intra	PARVG	Q9HBI0	KCTD7	Homo sapiens	Q96MP8-2	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	POU6F2	Homo sapiens	P78424	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	POU6F2	Homo sapiens	P78424	Y2H Array	32296183
Intra	PARVG	Q9HBI0	LHX3	Homo sapiens	Q9UBR4-2	Validated Y2H	32296183
Intra	PARVG	Q9HBI0	LHX3	Homo sapiens	Q9UBR4-2	Y2H Array	32296183
Intra	PARVG	Q9HBI0	LHX3	Homo sapiens	Q9UBR4-2	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	CDHR3	Homo sapiens	Q6ZTQ4	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	CDHR3	Homo sapiens	Q6ZTQ4	Y2H Array	32296183
Intra	PARVG	Q9HBI0	CSF3	Homo sapiens	Q8N4W3	Y2H Array	32296183
Intra	PARVG	Q9HBI0	CSF3	Homo sapiens	Q8N4W3	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	PARVG	Q9HBI0	a0a1u9x8x8_human	Homo sapiens	A0A1U9X8X8	Y2H Array	32296183
Intra	PARVG	Q9HBI0	a0a1u9x8x8_human	Homo sapiens	A0A1U9X8X8	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	32296183
Intra	PARVG	Q9HBI0	SERTAD2	Homo sapiens	Q14140	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	SERTAD2	Homo sapiens	Q14140	Y2H Array	32296183
Intra	PARVG	Q9HBI0	MEOX1	Homo sapiens	P50221	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	MEOX1	Homo sapiens	P50221	Y2H Array	32296183
Intra	PARVG	Q9HBI0	POLR2G	Homo sapiens	P62487	Y2H Array	32296183
Intra	PARVG	Q9HBI0	POLR2G	Homo sapiens	P62487	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	PDLIM7	Homo sapiens	Q9NR12	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	PDLIM7	Homo sapiens	Q9NR12	Validated Y2H	32296183
Intra	PARVG	Q9HBI0	PDLIM7	Homo sapiens	Q9NR12	Y2H Array	32296183
Intra	PARVG	Q9HBI0	GADD45A	Homo sapiens	P24522	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	GADD45A	Homo sapiens	P24522	Y2H Array	32296183
Intra	PARVG	Q9HBI0	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	PARVG	Q9HBI0	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	PARVG	Q9HBI0	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	PARVG	Q9HBI0	ANTKMT	Homo sapiens	Q9BQD7	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	ANTKMT	Homo sapiens	Q9BQD7	Y2H Array	32296183
Intra	PARVG	Q9HBI0	TLE5	Homo sapiens	Q08117	Y2H Prey Pooling	25416956
Intra	PARVG	Q9HBI0	TLE5	Homo sapiens	Q08117	Validated Y2H	25416956
Intra	PARVG	Q9HBI0	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	USHBP1	Homo sapiens	Q8N6Y0	Validated Y2H	25416956
Intra	PARVG	Q9HBI0	USHBP1	Homo sapiens	Q8N6Y0	Y2H Array	32296183
Intra	PARVG	Q9HBI0	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	PARVG	Q9HBI0	CFAP53	Homo sapiens	Q96M91	Y2H Array	32296183
Intra	PARVG	Q9HBI0	CFAP53	Homo sapiens	Q96M91	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	ZNF426	Homo sapiens	Q9BUY5	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	ZNF426	Homo sapiens	Q9BUY5	Y2H Array	32296183
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Y2H Array	25416956
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Anti Tag CoIP	33961781
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Y2H Array	32296183
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Anti Tag CoIP	28514442
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Y2H Array	31515488
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Validated Y2H	25416956
Intra	PARVG	Q9HBI0	ILK	Homo sapiens	Q13418	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	NDEL1	Homo sapiens	Q9GZM8	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	NDEL1	Homo sapiens	Q9GZM8	Y2H Array	32296183
Intra	PARVG	Q9HBI0	TRIB2	Homo sapiens	Q92519	Y2H Prey Pooling	32296183
Intra	PARVG	Q9HBI0	TRIB2	Homo sapiens	Q92519	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10076	PARVG Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	PARVG	VGNC	VGNC:44268
Rattus norvegicus	PARVG	RGD	RGD:1597417
Mus musculus	PARVG	MGD	MGI:2158329
Macaca mulatta	PARVG	VGNC	VGNC:75607
Bos taurus	PARVG	VGNC	VGNC:32591
Felis catus	PARVG	VGNC	VGNC:64047

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