LRP10 - LDL receptor related protein 10 Gene

Homo sapiens

Also known as LRP9; LRP-10; MST087; MSTP087

Gene ID: 26020 | Gene type: protein coding

About LRP10

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:22,871,740-22,881,713 (from NCBI)

This gene has 5 transcripts (splice variants), 177 orthologues and 14 paralogues. Ubiquitous expression in esophagus (RPKM 34.1), colon (RPKM 29.6) and 25 other tissues.

Summary

This gene encodes a low density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. [provided by RefSeq, Jul 2016]

LRP10 Products(2)

mRNA	Protein	Name
NM_001329226.2	NP_001316155.1	low-density lipoprotein receptor-related protein 10 isoform 2 precursor
NM_014045.5	NP_054764.2	low-density lipoprotein receptor-related protein 10 isoform 1 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRP10 Protein Structure

Ldl_recept_a

CUB

Ldl_recept_a

0
200
400
600
713 a.a.

Protein Preferred Names

Protein Names

low-density lipoprotein receptor-related protein 10

Recombinant LRP10 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76475	LRP-10 Protein, Human (HEK293, Fc)	Q7Z4F1-1 (H17-K440)	≥95%
HY-P76476	LRP-10 Protein, Human (HEK293, His)	Q7Z4F1-1 (H17-K440)	≥95%

Related Diseases

Diseases

Alias

Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies

Murcs Association	Mayer-Rokitansky-Kuster-Hauser Syndrome Type 2
Mrkh Syndrome Type 2	Mayer-Rokitansky-Küster-Hauser Syndrome Type 2
MURCS	Klippel-Feil Deformity, Conductive Deafness, And Absent Vagina
Atypical Mrkh Syndrome	Mullerian Duct Aplasia-Renal Dysplasia-Cervical Somite Anomalies Syndrome
Mayer-Rokitansky-Kuster-Hauser Syndrome, Type Ii	Mrkh, Type Ii
Mullerian Duct Aplasia, Unilateral Renal Aplasia, And Cervicothoracic Somite Dysplasia	Klippel-Feil Deformity - Conductive Deafness - Absent Vagina
Müllerian Aplasia - Renal Aplasia - Cervicothoracic Somite Dysplasia

Retinitis Pigmentosa 37

RP37	Retinitis Pigmentosa-37
Retinitis Pigmentosa, Type 37

Ovarian Embryonal Carcinoma

Embryonal Carcinoma Of Ovary

Embryonal Carcinoma Of The Ovary

Angiostrongyliasis

A. Cantonensis Angiostrongyliasis

Dementia, Lewy Body

Lewy Body Dementia	Lewy Body Disease
Diffuse Lewy Body Disease	Dementia With Lewy Bodies
DLB	Autosomal Dominant Diffuse Lewy Body Disease
Cortical Lewy Body Disease	Dementia, Lewy Body, Susceptibility To
Lewy Body Dementia, Susceptibility To	Senile Dementia Of The Lewy Body Type
Dementia Of The Lewy Body Type	Lbd
Diffuse Lewy Body Disease With Gaze Palsy	Dysphasic Dementia Hereditary
Lewy Body Type Senile Dementia	Lewy Body Variant Of Alzheimer Disease
Lewy Bodies	Lewy Body
Dlbd - [Diffuse Lewy Body Disease]	Clbd - [Cortical Lewy Body Disease]

Parkinson Disease, Late-Onset

Parkinson Disease	Parkinson'S Disease
PD	PARK
Parkinson Disease, Susceptibility To	Late Onset Parkinson'S Disease
Late Onset Parkinson Disease	Paralysis Agitans
Primary Parkinsonism	Idiopathic Parkinson Disease
Parkinson'S	Parkinson Disease, Late-Onset, Susceptibility To
Parkinson Disease, Age Of Onset, Modifier	Lewy Body Parkinson Disease
Idiopathic Parkinson'S Disease	Pd - [Parkinson Disease]
Parkinson Disease Nos	Parkinson, Nos
Primary Parkinson Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07793	LRP10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LRP10	MGD	MGI:1929480
Felis catus	LRP10	VGNC	VGNC:63284
Bos taurus	LRP10	VGNC	VGNC:30987
Rattus norvegicus	LRP10	RGD	RGD:1310471
Canis familiaris	LRP10	VGNC	VGNC:42772
Macaca mulatta	LRP10	VGNC	VGNC:74290
Others	LRP10	NCBI

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