2. Gene
  3. Ror1 - receptor tyrosine kinase-like orphan receptor 1 Gene

Ror1 - receptor tyrosine kinase-like orphan receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ntrkr1; 2810404D04Rik

Gene ID: 26563 | Gene type: protein coding

About Ror1

Summary

This gene encodes a receptor tyrosine kinase that has been implicated in nervous system development, specifically in the maintenance of neural progenitor cell fate, neurite extension and synapse formation. The encoded protein, likely a pseudokinase that lacks catalytic activity, may also regulate adipogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Ror1 Products(2)

mRNA Protein Name
NM_001312690.1 NP_001299619.1 inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform 2 precursor
NM_013845.5 NP_038873.2 inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in inner ear development IMP
IMP: Inferred from mutant phenotype
27162350 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axon terminus IDA
IDA: Inferred from direct assay
27162350 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inactive tyrosine-protein kinase transmembrane receptor ROR1

neurotrophic tyrosine kinase, receptor-related 1

tyrosine-protein kinase transmembrane receptor ROR1

Recombinant Ror1 Proteins

Cat. No. Product Name Accession Purity
HY-P78032 ROR1 Protein, Mouse (HEK293, His) Q9Z139 (Q30-Y406) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99201 Zilovertamab Inhibitor 98.21% Phase 3
HY-P99956 Zilovertamab vedotin Inducer 98.15% Phase 3
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139534 ARI-1 99.76% Unkown
HY-139534A (S)-ARI-1 Control 99.80% Unkown
HY-161096 Antitumor agent-127 99.09% Unkown
HY-117947 (R)-OR-S1 Control / Unkown
HY-162640 ROR1-IN-1 Inhibitor / Unkown
HY-170995 PROTAC ROR1 degrader-1 / Unkown
HY-170996 ROR1 ligand-1 Degrader / Unkown
HY-RS12124 ROR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-160790 β-Glu-PNP / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ror1 NCBI NCBI:4919
Canis familiaris Ror1 NCBI NCBI:489557
Rattus norvegicus Ror1 NCBI NCBI:362550