1. Gene
  2. FADS6 - fatty acid desaturase 6 Gene

FADS6 - fatty acid desaturase 6 Gene

Homo sapiens

Also known as FP18279

Gene ID: 283985 | Gene type: protein coding

About FADS6

This gene has 4 transcripts (splice variants), 190 orthologues and 3 paralogues. Biased expression in small intestine (RPKM 1.8), duodenum (RPKM 1.4) and 9 other tissues.

Summary

Predicted to enable oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. Predicted to be involved in lipid metabolic process. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

FADS6 Products(1)

mRNA Protein Name
NM_178128.6 NP_835229.3 fatty acid desaturase 6

FADS6 Protein Structure

FA_desaturase

FA_desaturase: Fatty acid desaturase (75 - 320)

  • 0
  • 100
  • 200
  • 300
  • 350 a.a.
Protein Preferred Names Protein Names

fatty acid desaturase 6

fatty acid desaturase domain family, member 6

FADS6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
FADS6 Q8N9I5 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
FADS6 Q8N9I5 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra
FADS6 Q8N9I5 PNKP Homo sapiens Q96T60
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 KRTAP1-5 Homo sapiens Q9BYS1
Y2H Array
32296183
Intra
FADS6 Q8N9I5 KRTAP1-5 Homo sapiens Q9BYS1
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 KRTAP1-5 Homo sapiens Q9BYS1
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 KRTAP6-3 Homo sapiens Q3LI67
Y2H Array
32296183
Intra
FADS6 Q8N9I5 KRTAP6-3 Homo sapiens Q3LI67
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
FADS6 Q8N9I5 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 KRTAP3-3 Homo sapiens Q9BYR6
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 KRTAP3-3 Homo sapiens Q9BYR6
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 KRTAP3-3 Homo sapiens Q9BYR6
Y2H Array
32296183
Intra
FADS6 Q8N9I5 DIABLO Homo sapiens Q9NR28
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
FADS6 Q8N9I5 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 FHL3 Homo sapiens Q13643
Y2H Array
32296183
Intra
FADS6 Q8N9I5 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 PBX3 Homo sapiens Q96AL5
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 INPP5K Homo sapiens Q9BT40
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 MTERF3 Homo sapiens Q96E29
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Intra
FADS6 Q8N9I5 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
FADS6 Q8N9I5 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 TNS2 Homo sapiens Q63HR2
Y2H Prey Pooling
32296183
Intra
FADS6 Q8N9I5 TNS2 Homo sapiens Q63HR2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Fetal Akinesia Deformation Sequence 4

FADS4

Fetal Akinesia Deformation Sequence Syndrome 4

Akinesia, Fetal, Deformation Sequence, Type 4

Fetal Akinesia Deformation Sequence 1

Fetal Akinesia Deformation Sequence

Fads

Fetal Akinesia Sequence

FADS1

Arthrogryposis Multiplex Congenita With Pulmonary Hypoplasia

Pena-Shokeir Syndrome Type 1

Fetal Akinesia Deformation Sequence Syndrome

Arthrogryposis Multiplex Congenita-Pulmonary Hypoplasia Syndrome

Arthrogryposis Multiplex Congenita Pulmonary Hypoplasia

Pena-Shokeir Syndrome, Type I

Foetal Akinesia Deformation Sequence Syndrome

Foetal Akinesia Sequence

Fetal Akinesia Deformation Sequence Syndrome 1

Pena-Shokeir Syndrome, Type 1

Pena Shokeir Syndrome, Type 1

Akinesia, Fetal, Deformation Sequence

Akinesia, Fetal, Deformation Sequence, Type 1

Pena-Shokeir Syndrome Type I

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus FADS6 VGNC VGNC:28704
Rattus norvegicus FADS6 RGD RGD:1311950
Canis familiaris FADS6 VGNC VGNC:40566
Felis catus FADS6 VGNC VGNC:62040
Mus musculus FADS6 MGD MGI:3039592