1. Gene
  2. NR3C1 - nuclear receptor subfamily 3 group C member 1 Gene

NR3C1 - nuclear receptor subfamily 3 group C member 1 Gene

Homo sapiens

Also known as GR; GCR; GRL; GCCR; GCRST

Gene ID: 2908 | Gene type: protein coding

About NR3C1

Cytogenetic location: 5q31.3 Genomic coordinates (GRCh38): 5:143,277,931-143,435,512 (from NCBI)

This gene has 17 transcripts (splice variants), 280 orthologues, 8 paralogues and is associated with 2 phenotypes. Ubiquitous expression in fat (RPKM 11.8), lung (RPKM 9.9) and 25 other tissues.

Summary

This gene encodes Glucocorticoid Receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of Other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

NR3C1 Products(22)

mRNA Protein Name
NM_001204264.2 NP_001191193.1 glucocorticoid receptor isoform alpha-D3
NM_001204261.2 NP_001191190.1 glucocorticoid receptor isoform alpha-C3
NM_001204263.2 NP_001191192.1 glucocorticoid receptor isoform alpha-D2
NM_001020825.2 NP_001018661.1 glucocorticoid receptor isoform beta
NM_001364183.2 NP_001351112.1 glucocorticoid receptor isoform gamma
NM_001364180.2 NP_001351109.1 glucocorticoid receptor isoform alpha
NM_001204258.2 NP_001191187.1 glucocorticoid receptor isoform alpha-B
NM_001204262.2 NP_001191191.1 glucocorticoid receptor isoform alpha-D1
NM_000176.3 NP_000167.1 glucocorticoid receptor isoform alpha
NM_001204265.2 NP_001191194.1 glucocorticoid receptor isoform GR-P
NM_001364182.1 NP_001351111.1 glucocorticoid receptor isoform alpha
NM_001018076.2 NP_001018086.1 glucocorticoid receptor isoform alpha
NM_001364185.1 NP_001351114.1 glucocorticoid receptor isoform gamma
NM_001018075.1 NP_001018085.1 glucocorticoid receptor isoform alpha
NM_001364181.2 NP_001351110.1 glucocorticoid receptor isoform alpha
NM_001018077.1 NP_001018087.1 glucocorticoid receptor isoform alpha
NM_001018074.1 NP_001018084.1 glucocorticoid receptor isoform alpha
NM_001204260.2 NP_001191189.1 glucocorticoid receptor isoform alpha-C2
NM_001204259.2 NP_001191188.1 glucocorticoid receptor isoform alpha-C1
NM_001364184.2 NP_001351113.1 glucocorticoid receptor isoform gamma
NR_157096.2
NM_001024094.2 NP_001019265.1 glucocorticoid receptor isoform gamma
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
16728402 GOA
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
15769988 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
1894621 GOA
enables Hsp90 protein binding IPI
IPI: Inferred from physical interaction
26593036 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16728402 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
1894621 GOA
enables TBP-class protein binding IPI
IPI: Inferred from physical interaction
19841061 GOA
enables core promoter sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17081986 GOA
enables nuclear receptor activity IDA
IDA: Inferred from direct assay
17635946 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9079630 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
20371704 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
enables steroid binding IDA
IDA: Inferred from direct assay
15769988 GOA
enables steroid hormone binding IDA
IDA: Inferred from direct assay
17635946 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15769988 GOA
located in nuclear speck IDA
IDA: Inferred from direct assay
9353307 GOA
is active in nucleus IDA
IDA: Inferred from direct assay
28139699 GOA
located in nucleus IDA
IDA: Inferred from direct assay
9353307 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
26593036 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NR3C1 Protein Structure

GCR

GCR: Glucocorticoid receptor (26 - 401)

zf-C4

zf-C4: Zinc finger, C4 type (two domains) (420 - 487)

Hormone_recep

Hormone_recep: Ligand-binding domain of nuclear hormone receptor (544 - 735)

  • 0
  • 200
  • 400
  • 600
  • 777 a.a.
Protein Preferred Names Protein Names

glucocorticoid receptor

nuclear receptor subfamily 3 group C member 1 variant hGR-B(54)

nuclear receptor subfamily 3 group C member 1 variant hGR-B(77)

nuclear receptor subfamily 3 group C member 1 variant hGR-B(93)

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

NR3C1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
NR3C1 P04150 LCK Homo sapiens P06239
Anti Bait CoIP
16888650
Intra
NR3C1 P04150 HSP90AA1 Homo sapiens P07900
EM
24949977
Intra
NR3C1 P04150 HSP90AA1 Homo sapiens P07900
MAPPIT
31467278
Intra
NR3C1 P04150 HSP90AA1 Homo sapiens P07900
Pull Down
24949977
Intra
NR3C1 P04150 HSP90AA1 Homo sapiens P07900
GMS
24949977
Intra
NR3C1 P04150 HSP90AA1 Homo sapiens P07900
Crosslink
24949977
Intra
NR3C1 P04150 AKT1 Homo sapiens P31749
Pull Down
24291004
Intra
NR3C1 P04150 AKT1 Homo sapiens P31749
Protein Kinase Assay
24291004
Intra
NR3C1 P04150 AKT1 Homo sapiens P31749
Anti Tag CoIP
24291004
Intra
NR3C1 P04150 EGFR Homo sapiens P00533
Ub Reconstruction
24658140
Intra
NR3C1 P04150 CD4 Homo sapiens P01730
Anti Bait CoIP
16888650
Intra
NR3C1 P04150 KIAA0408 Homo sapiens Q6ZU52
Display Tech
20195357
Intra
NR3C1 P04150 RXRB Homo sapiens P28702
Y2H Array
20211142
Cross
NR3C1 P04150 Mvp Rattus norvegicus Q62667
Y2H
16619302
Cross
NR3C1 P04150 Mvp Rattus norvegicus Q62667
Pull Down
16619302
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Conn'S Syndrome

Cushing Syndrome

Hyperaldosteronism

Primary Hyperaldosteronism

Hypercortisolism

Primary Aldosteronism

Cushing'S Syndrome

Adrenal Gland Hyperfunction

Conn Syndrome

Hyperadrenalism

Ectopic Acth Syndrome

Hyperadrenocorticism

Cushing Disease

Adrenal Cortex Adenoma

Corticotroph Pituitary Adenoma

Cushing'S Disease

Pituitary Corticotroph Micro-Adenoma

Pituitary-Dependent Cushing Syndrome

Pituitary Acth Hypersecretion

Acth Syndrome, Ectopic

Acth-Secreting Pituitary Adenoma

Adrenal Hyperfunction Resulting From Pituitary Acth Excess

Ectopic Adrenocorticotropic Hormone Syndrome

Nodular Primary Adrenocortical Dysplasia

Pituitary Dependent Cushing Syndrome

Pituitary Cushing Syndrome

Pituitary-Dependant Cushing Syndrome

Pituitary-Dependant Hypercortisolism

Pituitary-Dependant Hypercortisolism Disorder

Aldosteronism Primary

Acth Syndrome Ectopic

Adrenal Cushing'S Syndrome

Adrenal Cortical Adenoma

Cushing Syndrome Nos

Cortisol Hypersecretion

Corticoadrenal Hypersecretion

Cushing Syndrome Secondary To Ectopic Acth-Secretion

Ectopic Cushing Syndrome

Hypercortisolism Due To Nonpituitary Tumour

Ectopic Acth - [Adrenocorticotropic Hormone] Secretion

Ectopic Acth - [Adrenocorticotropic Hormone] Secretion Causing Cushing Syndrome

Idiopathic Aldosteronism

Aldosteronism

Primary Aldosteronism Due To Bilateral Adrenal Hyperplasia

Primary Aldosteronism Due To Adrenal Hyperplasia

Skin Atrophy

Atrophic Condition Of Skin

Atrophoderma

Atrophy - Skin

Acquired Immunodeficiency Syndrome

Acquired Immune Deficiency Syndrome

AIDS

Acquired Immune Deficiency

Acquired Immunodeficiency

Acquired Immunodeficiency Due To Protein Loss

Acute Stress Disorder

Traumatic Stress Disorder

Stress Disorders, Traumatic, Acute

Stress Disorders, Traumatic

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Nelson Syndrome

Nelson'S Syndrome

Dermal Ridges

Ridges-Off-The-End Syndrome

Postadrenalectomy Cushing Syndrome

Pseudohypoaldosteronism
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Obesity , Susceptibility To

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Alzheimer Disease 16

AD16

Alzheimer'S Disease 16

Alzheimer'S Disease 16, Late Onset

Hyperandrogenism

Hyperandrogenization Syndrome

Osteoporosis

Postmenopausal Osteoporosis

Osteoporosis, Postmenopausal

Bone Mineral Density Quantitative Trait Locus

Bmnd

Osteoporosis, Involutional

Osteoporosis, Susceptibility To

Osteoporosis, Postmenopausal, Susceptibility

Bone Mineral Density Variation Qtl, Osteoporosis

OSTEOP

Involutional Osteoporosis

Senile Osteoporosis

Osteoporosis Postmenopausal

Bone Mineral Density, Quantitative Trait Locus

Osteoporosis, Senile

Idiopathic Osteoporosis

Bone Rarefaction Nos

Type 1 Osteoporosis

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Chronic Fatigue Syndrome

Myalgic Encephalomyelitis

Postviral Fatigue Syndrome

Cfs

Myalgic Encephalitis

Encephalomyelitis, Myalgic

Chronic Fatigue

Fatigue Syndrome, Chronic

Benign Myalgic Encephalomyelitis

Akureyri

Akureyri Disease

Cfs - [Chronic Fatigue Syndrome]

Epidemic Neuromyasthenia

Myalgic Encephalomyelitis Syndrome

Me - [Myalgic Encephalomyelitis]

Pvfs - [Postviral Fatigue Syndrome]

Neuromyasthenia

Iceland Disease

Icelandic Disease

Atypical Depressive Disorder

Atypical Depression

Giant Cell Reparative Granuloma

Central Giant Cell Granuloma

Central Giant Cell Reparative Granuloma Of Jaw

Central Giant Cell Granuloma

Granuloma, Giant Cell

Granuloma, Giant Cell Reparative

Giant Cell Lesion Of Small Bones

Giant Cell Granuloma, Nos

Adult Syndrome

Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome

Acro Dermato Ungual Lacrimal Tooth Syndrome

Pigment Anomaly-Ectrodactyly-Hypodontia Syndrome

Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome

Adult

Generalized Anxiety Disorder

Anxiety Generalized

Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration

Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3

Pituitary Adenoma

Pituitary Neoplasms

Adenoma Of The Pituitary Gland

Pituitary Adenomas

Adenoma, Pituitary

Pituitary Gland Adenoma

Rhinitis

Runny Nose

Diabetes Mellitus

Diabetes

Acth-Secreting Pituitary Adenoma

Acth-Producing Pituitary Adenoma

Corticotroph Adenoma

Corticotropinoma

Pituitary-Dependent Cushing'S Disease

Adrenal Gland Hyperfunction

Cushing Syndrome

Hyperaldosteronism, Familial, Type I

Glucocorticoid-Remediable Aldosteronism

Gra

Familial Hyperaldosteronism Type 1

HALD1

Fh I

Glucocorticoid-Suppressible Hyperaldosteronism

Gsh

Acth-Dependent Hyperaldosteronism Syndrome

Aldosteronism, Glucocorticoid-Remediable

Dexamethasone Sensitive Hypertension

Glucocorticoid Sensitive Hypertension

Hyperaldosteronism, Familial Type 1

Familial Hyperaldosteronism Type I

Fh1

Aldosteronism, Sensitive To Dexamethasone

Dexamethasone-Sensitive Hypertension

Fh-I

Glucocorticoid-Sensitive Hypertension

Hyperaldosteronism, Familial, 1

Aldosteronism Sensitive To Dexamethasone

Familial Hyperaldosteronism 1

Fh Type 1

Familial Aldosteronism Type I

Glucocorticoid Resistance, Generalized

Glucocorticoid Resistance

Glucocorticoid Receptor Deficiency

Cortisol Resistance From Glucocorticoid Receptor Defect

GCCR

Gccr Deficiency

Gcr Deficiency

Grl Deficiency

Generalized Glucocorticoid Resistance Syndrome

GCRES

Cortisol Resistance

Chrousos Syndrome

Adrenal Cortex Disease

Adrenal Cortex Diseases

Major Depressive Disorder

Seasonal Affective Disorder

Unipolar Depression

Depression

MDD

Depressive Disorder

Unipolar Depression, Susceptibility To

Major Depressive Disorder 1

Major Depressive Disorder, Response To Citalopram Therapy In

Major Depressive Disorder 2

Winter Depression

Single Major Depressive Episode

Sad

Clinical Depression

Major Depression

Depressive Syndrome

Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment

Seasonal Affective Disorder, Susceptibility To

Recurrent Major Depression

Affective Disorder, Seasonal

Depression In A Seasonal Pattern

Depression

Seasonal

Major Depressive Disorder With A Seasonal Pattern

Seasonal Depression

Seasonal Mood Disorder

Mental Depression

Recurrent Major Depressive Episodes

Bipolar Disorder

Bipolar Depression

Manic Disorder

Depression, Bipolar

Bipolar Disorder Manic Phase

Depressive-Manic Psych.

Manic Bipolar Affective Disorder

Manic Bipolar I Disorder

Manic Depression

Manic Depressive Disorder

Mixed Bipolar Disorder

Bipolar Affective Disorder

Bipolar Affective Psychosis

Bipolar Spectrum Disorder

Manic Depressive Illness

Depression Bipolar

Bipolar Disorder, Mixed

Major Affective Disorder

Major Affective Disorder 1

Major Affective Disorder 2

Pituitary-Dependent Cushing'S Disease

Pituitary-Dependent Cushing Disease

Pituitary Acth Hypersecretion

Overproduction Of Acth

Pituitary-Dependent Cushings Disease

Overproduction Of Pituitary Acth

Pituitary-Dependent Hyperadrenocorticism

Corticotroph Pituitary Adenoma

Acth- [Adrenocorticotropic Hormone] Secreting Pituitary Adenoma

Cushing Syndrome Or Disease, Pituitary-Dependent

Cushings Basophilism

Cushing'S Syndrome 3

Itsenko-Cushing Syndrome

Itsenko Disease

Pituitary Basophilism

Pituitary-Dependent Hypercorticalism

Suprarenogenic Syndrome

Cushing Disease

Cushing'S Disease

Trichothiodystrophy 7, Nonphotosensitive

TTD7

Nonphotosensitive Trichothiodystrophy 7

Trichothiodystrophy 7, Non-Photosensitive

Personality Disorder

Personality Disorders

Character Disorder

Personality

Specific Personality Disorders

Enduring Personality Change After Psychiatric Illness

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Cerebral Angioma

Hemangioma Of Cerebrum

Cerebral Hemangioma

Adrenal Gland Disease

Adrenal Gland Diseases

Adrenal Gland Disorders

Pylorus Cancer

Ca Pylorus - Stomach

Malignant Neoplasm Of Prepylorus

Malignant Neoplasm Of Pylorus Of Stomach

Malignant Tumor Of Pylorus

Malignant Neoplasm Of Pylorus

Cataract

Cataracts

Cat - [Cataract]

Cataract Form

Lens Opacity

Lens Opacities

Mood Disorder

Mood Disorders

Episodic Mood Disorder

Mental Depression

Depression

Depressive Disorder

Abnormality Of Glucagon Secretion

Glucagon Secretion Abnormality

Abnormality Of Secretion Of Glucagon

Myeloma, Multiple

Multiple Myeloma

Kahler Disease

Myelomatosis

Plasma Cell Myeloma

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler'S Disease

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Ovarian Serous Adenofibroma
Endogenous Depression

Clinical Depression

Unipolar Depression

Depressive Disorder

Hypoglycemia

Hypoglycaemia

Low Blood Sugar

Hypoglycaemia Nos

Spontaneous Hypoglycaemia

Nondiabetic Hypoglycaemia

Hypoglycaemic Disorder Nos

Hypoglycaemic Syndrome

Childhood Acute Lymphocytic Leukemia

Childhood Acute Lymphoblastic Leukemia

Childhood All

Pediatric Acute Lymphoblastic Leukemia

Lymphoblastic Leukemia Acute Childhood

Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Postpartum Depression

Maternity Blues

Postnatal Depression

Depression, Postpartum

Post-Partum Depression

Depression Postpartum

Mediastinal Lipomatosis
Nephrotic Syndrome

Finnish Congenital Nephrotic Syndrome

Ns - [Nephrotic Syndrome]

Nephrosis Syndrome

Nephrosis Nos

Glomerular Lesion Nephrosis

Post-Traumatic Stress Disorder

PTSD

Traumatic Neurosis

Post Traumatic Stress Disorder

Stress Disorders, Post-Traumatic

Posttraumatic Stress Disorder

Ptsd - [Post Traumatic Stress Disorder]

Trauma-Related Disorders

Ocular Hypertension

Hypertension, Ocular

Intraocular Pressure Increase

Oh - [Ocular Hypertension]

Oht - [Ocular Hypertension]

Lipoid Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency

Congenital Lipoid Adrenal Hyperplasia

Lipoid Cah

Lipoid Adrenal Hyperplasia

Adrenal Hyperplasia 1

Cah

Clah

LCAH

Adrenal Hyperplasia I

Lipoid Hyperplasia, Congenital, Of Adrenal Cortex With Male Pseudohermaphroditism

Congenital Adrenal Hyperplasia Lipoid

Adrenal Hyperplasia, Congenital

Congenital Adrenal Hyperplasia, Lipoid

AH1

Congenital Lipoid Hyperplasia Of Adrenal Cortex With Male Pseudohermaphroditism

Adrenal Hyperplasia Congenital

Hyperplasia, Adrenal, Lipoid, Congenital

Congenital Adrenogenital Disorders Associated With Enzyme Deficiency

Congenital Adrenal Cortical Hyperplasia

Congenital Adrenal Gland Hyperplasia

Congenital Adrenogenital Syndrome

Congenital Hyperadrenocorticism

Congenital Adrenogenitalism

Congenital Female Adrenal Pseudohermaphroditism

Ectopic Cushing Syndrome

Cushing Syndrome Due To Ectopic Acth Secretion

Ectopic Acth Secreting Tumor

Adrenocorticotropic Hormone Secretion Syndrome

Occult Ectopic Acth Secretion

Paraneoplastic Cushing Syndrome

Pulmonary Disease, Chronic Obstructive

Chronic Obstructive Pulmonary Disease

COPD

Pulmonary Disease, Chronic Obstructive, Severe Early-Onset

Chronic Obstructive Lung Disease

Chronic Obstructive Airway Disease

Pulmonary Disease, Chronic Obstructive, Susceptibility To

Cold

Severe Early-Onset Chronic Obstructive Pulmonary Disease

Pulmonary Disease Chronic Obstructive

Pulmonary Disease, Obstructive, Chronic, Susceptibility To

Chronic Obstructive Pulmonary Disease Of Horses

Common Cold

Upper Respiratory Infections

Copd - [Chronic Obstructive Pulmonary Disease]

Coad - [Chronic Obstructive Airways Disease]

Cold - [Chronic Obstructive Lung Disease]

Chronic Airway Disease Nos

Chronic Airways Limitation, Unspecified

Chronic Obstructed Airway, Unspecified

Chronic Obstructive Airway Disease, Unspecified

Chronic Obstructive Airway, Unspecified

Obstructive Lung Disease Nos

Chronic Obstructive Lung Disease Nos

Chronic Obstructive Lung Nos

Obstructive Pulmonary Disease Nos

Exacerbation Copd Nos

Acute Exacerbation Copd

Borderline Personality Disorder
Sudden Infant Death Syndrome

SIDS

Sudden Infant Death Syndrome, Susceptibility To

Cot Death

Crib Death

Sudden Death Of Nonspecific Cause In Infancy

Sudden Infant Death

Death, Sudden, Syndrome, Infant

Anxiety

Anxiety Disorder

Anxiety Disorders

Anxiety State

Anxieties

Anxiety Neurosis

Steroid-Induced Glaucoma

Corticosteroid-Induced Glaucoma

Corticosteroid-Binding Globulin Deficiency

CBG DEFICIENCY

Transcortin Deficiency

Allergic Rhinitis

Hay Fever

Allergic Rhinitis, Susceptibility To

ALRH

Atopic Rhinitis

Seasonal Allergic Rhinitis

Non-Seasonal Allergic Rhinitis

Perenial Allergic Rhinitis

Pollenosis

Rhinitis Allergic Seasonal

Rhinitis, Allergic, Perennial

Allergic Rhinitis, Cause Unspecified

Pollinosis

Pollen Allergy

Allergy Nos Due To Pollen

Summer Catarrh

Other Seasonal Allergic Rhinitis

Hypokalemia

Potassium Deficiency

Potassium Deficiency Disorder

Hypopotassemia

Potassium

Potassium [K] Deficiency

Hypokalaemic Syndrome

Hypopotassaemia

Hypopotassaemia Syndrome

Hypokalaemic

Potassium Depletion

Liddle Syndrome 1

Liddle Syndrome

Pseudoaldosteronism

LIDLS1

Lidls

Pseudohyperaldosteronism

Liddle'S Syndrome

Pseudoprimary Hyperaldosteronism

Pseudohyperaldosteronism Type 1

Liddles Syndrome

Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Diabetes Mellitus, Non-Insulin-Dependent

Type 2 Diabetes

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

Glucocorticoid-Induced Osteoporosis

Steroid-Induced Osteoporosis

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris NR3C1 VGNC VGNC:43952
Macaca mulatta NR3C1 VGNC VGNC:75515
Felis catus NR3C1 VGNC VGNC:102270
Bos taurus NR3C1 VGNC VGNC:32243
Mus musculus NR3C1 MGD MGI:95824
Rattus norvegicus NR3C1 RGD RGD:2741
Others NR3C1 NCBI