RAB41 - RAB41, member RAS oncogene family Gene

Homo sapiens

Gene ID: 347517 | Gene type: protein coding

About RAB41

This gene has 3 transcripts (splice variants), 69 orthologues and 68 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]

RAB41 Products(2)

mRNA	Protein	Name
NM_001032726.3	NP_001027898.2	ras-related protein Rab-41 isoform 1
NM_001363807.1	NP_001350736.1	ras-related protein Rab-41 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB41 Protein Structure

Ras

0
100
200
222 a.a.

Protein Preferred Names

Protein Names

ras-related protein Rab-41

RAB41, member RAS homolog family

RAB41 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	RAB41	Q5JT25	REL	Homo sapiens	Q04864	Y2H Prey Pooling	25416956
Intra	RAB41	Q5JT25	REL	Homo sapiens	Q04864	Y2H Array	25416956
Intra	RAB41	Q5JT25	TCF4	Homo sapiens	P15884	Y2H Prey Pooling	25416956
Intra	RAB41	Q5JT25	TCF4	Homo sapiens	P15884	Validated Y2H	25416956
Intra	RAB41	Q5JT25	PPP5C	Homo sapiens	P53041	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Microvillus Inclusion Disease

Congenital Microvillous Atrophy	Intractable Diarrhea Of Infancy
Congenital Familial Protracted Diarrhea With Enterocyte Brush-Border Abnormalities	Davidson Disease
Microvillous Inclusion Disease	Congenital Microvillus Atrophy
Mvid	Diarrhea 2 With Microvillus Atrophy
Mvd	Congenital Familial Protracted Diarrhea
Davidson'S Disease	Familial Enteropathy, Microvillus
Microvillus Atrophy, Congenital	Congenital Enteropathy
Familial Protracted Enteropathy	Microvillous Atrophy
Microvillus Atrophy With Diarrhea 2	Idi

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11565	RAB41 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Name
Email *

	Sorry, but the email address you supplied was invalid.