DPPA3 - developmental pluripotency associated 3 Gene

Homo sapiens

Also known as Pgc7; STELLA

Gene ID: 359787 | Gene type: protein coding

About DPPA3

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,711,433-7,717,559 (from NCBI)

This gene has 1 transcript (splice variant) and 73 orthologues. Low expression observed in reference dataset.

Summary

This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. [provided by RefSeq, Jul 2008]

DPPA3 Products(1)

mRNA	Protein	Name
NM_199286.4	NP_954980.1	developmental pluripotency-associated protein 3

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	21421998	GOA
located in nucleus	IDA IDA: Inferred from direct assay	21421998	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPPA3 Protein Structure

PGC7_Stella

0
100
159 a.a.

Protein Preferred Names

Protein Names

developmental pluripotency-associated protein 3

stella-related protein

DPPA3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	DPPA3	Q6W0C5	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
Intra	DPPA3	Q6W0C5	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	DEPDC5	Homo sapiens	O75140-2	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	DEPDC5	Homo sapiens	O75140-2	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	KRT76	Homo sapiens	Q01546	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	KRT76	Homo sapiens	Q01546	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	KRT27	Homo sapiens	Q7Z3Y8	Validated Y2H	32296183
Intra	DPPA3	Q6W0C5	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	NUP62	Homo sapiens	P37198	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	NUP62	Homo sapiens	P37198	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	DYNLL1	Homo sapiens	P63167	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	DYNLL1	Homo sapiens	P63167	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	HAUS7	Homo sapiens	Q99871	Validated Y2H	32296183
Intra	DPPA3	Q6W0C5	HAUS7	Homo sapiens	Q99871	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	HAUS7	Homo sapiens	Q99871	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	TRIB3	Homo sapiens	Q96RU7	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	TRIB3	Homo sapiens	Q96RU7	Validated Y2H	32296183
Intra	DPPA3	Q6W0C5	TRIB3	Homo sapiens	Q96RU7	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	ZNF618	Homo sapiens	Q5T7W0	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	ZNF618	Homo sapiens	Q5T7W0	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	DYNLL2	Homo sapiens	Q96FJ2	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	DYNLL2	Homo sapiens	Q96FJ2	Validated Y2H	32296183
Intra	DPPA3	Q6W0C5	DYNLL2	Homo sapiens	Q96FJ2	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	SERTAD3	Homo sapiens	Q9UJW9	Y2H Prey Pooling	32296183
Intra	DPPA3	Q6W0C5	SERTAD3	Homo sapiens	Q9UJW9	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	SERTAD3	Homo sapiens	Q9UJW9	Validated Y2H	32296183
Intra	DPPA3	Q6W0C5	PLEKHG4	Homo sapiens	Q58EX7	Y2H Array	32296183
Intra	DPPA3	Q6W0C5	PLEKHG4	Homo sapiens	Q58EX7	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Arthrogryposis, Distal, Type 1a

Distal Arthrogryposis Type 1	Digitotalar Dysmorphism
DA1A	Da1
Amcd1	Arthrogryposis, Distal, Type 2b4
Distal Arthrogryposis Type 1a	Arthrogryposis, Distal, Type 1
Arthrogryposis Multiplex Congenita Distal Type 1	Arthrogryposis Multiplex Congenita, Distal Type 1
Arthrogryposis Multiplex Congenita, Distal, Type I	Distal Arthrogryposis Type 1b
Arthrogryposis, Distal, 1a	Amc
Arthrogryposis Multiplex Congenita	Arthrogryposis, Distal, 2b4
DA2B4	Arthrogryposis Multiplex Congenita, Distal, Type 1
Arthrogryposis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03971	DPPA3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	DPPA3	RGD	RGD:1310932
Mus musculus	DPPA3	MGD	MGI:1920958

Name
Email *

	Sorry, but the email address you supplied was invalid.