OPRD1 - opioid receptor delta 1 Gene

Homo sapiens

Also known as DOP; DOR; DOR1; OPRD

Gene ID: 4985 | Gene type: protein coding

About OPRD1

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:28,812,170-28,871,267 (from NCBI)

This gene has 1 transcript (splice variant), 253 orthologues and 17 paralogues. Low expression observed in reference dataset.

Summary

Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled Opioid Receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Is intrinsic component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OPRD1 Products(1)

mRNA	Protein	Name
NM_000911.4	NP_000902.3	delta-type opioid receptor

OPRD1 Protein Structure

7tm_1

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

delta-type opioid receptor

D-OR-1

Related Diseases

Diseases

Alias

Morphine Dependence

Heroin Dependence

Neonatal Abstinence Syndrome

Drug Withdrawal Syndrome In Newborn

Drug Dependence

Opiate Dependence

Opioid Dependence	Opioid Addiction
Opiate Addiction	Opioid Type Dependence
Opioid-Related Disorders	Opium Dependence
Narcotic Dependence	Intravenous Narcotism
Narcotism Nos	Oral Narcotism Nos

Substance Dependence

Pertussis

Whooping Cough	Bordetella Infections
Bordetella Infection	Bordetella Pertussis Infection
Wc - Whooping Cough	Whooping Cough Due To Unspecified Organism
Bordetellosis	Tussis Convulsiva
Whooping Cough, Unspecified Organism	Wc - [Whooping Cough]
Whooping Cough Due To B. Parapertussis	Infection Due To Bordetella Parapertussis

Opioid Abuse

Opioid-Related Disorders

Alcohol Dependence

Alcoholism	Alcohol Dependence, Susceptibility To
Alcohol Dependence, Protection Against	Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against
Alcoholism, Susceptibility To	Alcoholic Intoxication, Chronic
Pharyngeal Neoplasms	Chronic Alcoholism
Dipsomania	Alcohol Addiction
Ethanol Dependence	Chronic Ethanolism
Chronic Alcoholic Disease Nos	Alcoholic Disease Nos
Alcoholic

Cocaine Dependence

Pain Agnosia

Analgesia

Agnosia

Dyspraxia	Primary Visual Agnosia
Dyspraxia Syndrome	Monomodal Visual Amnesia
Visual Amnesia	Agnosia, Primary Visual
Apraxias	Alexia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09801	OPRD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-116163	ML350		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	OPRD1	MGD	MGI:97438
Felis catus	OPRD1	VGNC	VGNC:68632
Bos taurus	OPRD1	VGNC	VGNC:50539
Canis familiaris	OPRD1	VGNC	VGNC:44132
Macaca mulatta	OPRD1	VGNC	VGNC:75589
Rattus norvegicus	OPRD1	RGD	RGD:3233
Others	OPRD1	NCBI

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