2. Gene
  3. CTXN3 - cortexin 3 Gene

CTXN3 - cortexin 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KABE

Gene ID: 613212 | Gene type: protein coding

About CTXN3

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:127,649,082-127,658,630 (from NCBI)

This gene has 4 transcripts (splice variants), 141 orthologues and 2 paralogues. Restricted expression toward kidney (RPKM 21.3).

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

CTXN3 Products(2)

mRNA Protein Name
NM_001048252.3 NP_001041717.1 cortexin-3
NM_001127385.2 NP_001120857.1 cortexin-3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CTXN3 Protein Structure

Cortexin

Cortexin: Cortexin of kidney (1 - 81)

  • 0
  • 81 a.a.
Protein Preferred Names Protein Names

cortexin-3

kidney and brain-expressed protein

CTXN3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra CTXN3 Q4LDR2 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 LDLRAD1 Homo sapiens Q5T700
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
Intra CTXN3 Q4LDR2 NCAPH2 Homo sapiens Q6IBW4-4
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 NCAPH2 Homo sapiens Q6IBW4-4
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 NCAPH2 Homo sapiens Q6IBW4-4
Y2H Array
32296183
Intra CTXN3 Q4LDR2 LSMEM2 Homo sapiens Q8N112
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 LSMEM2 Homo sapiens Q8N112
Y2H Array
32296183
Intra CTXN3 Q4LDR2 LSMEM2 Homo sapiens Q8N112
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 CTLA4 Homo sapiens P16410
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CTLA4 Homo sapiens P16410
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 ATP1B3 Homo sapiens P54709
Y2H Array
32296183
Intra CTXN3 Q4LDR2 ATP1B3 Homo sapiens P54709
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 MGST2 Homo sapiens Q99735
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 MGST2 Homo sapiens Q99735
Y2H Array
32296183
Intra CTXN3 Q4LDR2 MGST2 Homo sapiens Q99735
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 TMEM179B Homo sapiens Q7Z7N9
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TMEM179B Homo sapiens Q7Z7N9
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TMEM179B Homo sapiens Q7Z7N9
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CLDN14 Homo sapiens O95500
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CLDN14 Homo sapiens O95500
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 MFF Homo sapiens Q9GZY8-5
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 MFF Homo sapiens Q9GZY8-5
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CLEC17A Homo sapiens Q6ZS10
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CLEC17A Homo sapiens Q6ZS10
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CLEC17A Homo sapiens Q6ZS10
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 CLEC7A Homo sapiens Q9BXN2-6
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 CLEC7A Homo sapiens Q9BXN2-6
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CLEC7A Homo sapiens Q9BXN2-6
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 STOM Homo sapiens P27105
Y2H Array
32296183
Intra CTXN3 Q4LDR2 STOM Homo sapiens P27105
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra CTXN3 Q4LDR2 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra CTXN3 Q4LDR2 GPR61 Homo sapiens Q9BZJ8
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 GPR61 Homo sapiens Q9BZJ8
Y2H Array
32296183
Intra CTXN3 Q4LDR2 GPR61 Homo sapiens Q9BZJ8
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 FUT7 Homo sapiens Q11130
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 FUT7 Homo sapiens Q11130
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TLCD4 Homo sapiens Q96MV1
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra CTXN3 Q4LDR2 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra CTXN3 Q4LDR2 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra CTXN3 Q4LDR2 KIR3DL3 Homo sapiens Q8N743
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 KIR3DL3 Homo sapiens Q8N743
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 KIR3DL3 Homo sapiens Q8N743
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CLRN1 Homo sapiens P58418
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CLRN1 Homo sapiens P58418
Y2H Array
32296183
Intra CTXN3 Q4LDR2 AQP9 Homo sapiens O43315
Y2H Array
32296183
Intra CTXN3 Q4LDR2 AQP9 Homo sapiens O43315
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra CTXN3 Q4LDR2 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 SPACA1 Homo sapiens Q9HBV2
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
Intra CTXN3 Q4LDR2 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 GJB1 Homo sapiens P08034
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 GJB1 Homo sapiens P08034
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TMEM167B Homo sapiens Q9NRX6
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TMEM167B Homo sapiens Q9NRX6
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TMEM167B Homo sapiens Q9NRX6
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 FFAR3 Homo sapiens O14843
Y2H Array
32296183
Intra CTXN3 Q4LDR2 FFAR3 Homo sapiens O14843
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 BTN2A1 Homo sapiens Q7KYR7-4
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 BTN2A1 Homo sapiens Q7KYR7-4
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 BTN2A1 Homo sapiens Q7KYR7-4
Y2H Array
32296183
Intra CTXN3 Q4LDR2 ADGRG3 Homo sapiens Q86Y34
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 ADGRG3 Homo sapiens Q86Y34
Y2H Array
32296183
Intra CTXN3 Q4LDR2 ADGRG3 Homo sapiens Q86Y34
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CD300E Homo sapiens Q496F6
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CD300E Homo sapiens Q496F6
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CPLX4 Homo sapiens Q7Z7G2
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra CTXN3 Q4LDR2 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 SLC10A2 Homo sapiens Q12908
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 SLC10A2 Homo sapiens Q12908
Y2H Array
32296183
Intra CTXN3 Q4LDR2 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra CTXN3 Q4LDR2 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TSPAN12 Homo sapiens O95859
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TSPAN12 Homo sapiens O95859
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CERS4 Homo sapiens Q9HA82
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CERS4 Homo sapiens Q9HA82
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 CERS4 Homo sapiens Q9HA82
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 OPRD1 Homo sapiens P41143
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 OPRD1 Homo sapiens P41143
Y2H Array
32296183
Intra CTXN3 Q4LDR2 PLPP5 Homo sapiens Q8NEB5
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 PLPP5 Homo sapiens Q8NEB5
Y2H Array
32296183
Intra CTXN3 Q4LDR2 PLPP5 Homo sapiens Q8NEB5
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TMEM106C Homo sapiens Q9BVX2
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 TMEM106C Homo sapiens Q9BVX2
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TMEM106C Homo sapiens Q9BVX2
Y2H Array
32296183
Intra CTXN3 Q4LDR2 LAPTM4B Homo sapiens Q86VI4
Y2H Array
32296183
Intra CTXN3 Q4LDR2 LAPTM4B Homo sapiens Q86VI4
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 LAPTM4B Homo sapiens Q86VI4
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 IFNLR1 Homo sapiens Q8IU57
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 IFNLR1 Homo sapiens Q8IU57
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 IFNLR1 Homo sapiens Q8IU57
Y2H Array
32296183
Intra CTXN3 Q4LDR2 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra CTXN3 Q4LDR2 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 PVR Homo sapiens P15151
Y2H Array
32296183
Intra CTXN3 Q4LDR2 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 PACC1 Homo sapiens Q9H813
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 PACC1 Homo sapiens Q9H813
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 PACC1 Homo sapiens Q9H813
Y2H Array
32296183
Intra CTXN3 Q4LDR2 EDA Homo sapiens Q92838
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 EDA Homo sapiens Q92838
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 EDA Homo sapiens Q92838
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TM4SF19 Homo sapiens Q96DZ7
Y2H Array
32296183
Intra CTXN3 Q4LDR2 TM4SF19 Homo sapiens Q96DZ7
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 TM4SF19 Homo sapiens Q96DZ7
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CD53 Homo sapiens P19397
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CD53 Homo sapiens P19397
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra CTXN3 Q4LDR2 BIK Homo sapiens Q13323
Y2H Array
32296183
Intra CTXN3 Q4LDR2 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra CTXN3 Q4LDR2 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 KASH5 Homo sapiens Q8N6L0
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra CTXN3 Q4LDR2 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra CTXN3 Q4LDR2 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra CTXN3 Q4LDR2 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra CTXN3 Q4LDR2 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra CTXN3 Q4LDR2 KLRC1 Homo sapiens P26715
Y2H Array
32296183
Intra CTXN3 Q4LDR2 KLRC1 Homo sapiens P26715
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Neurofibromatosis, Type Ii

Neurofibromatosis 2

Neurofibromatosis, Type 2

NF2

Neurofibromatosis Type Ii

Bilateral Acoustic Neurofibromatosis

Banf

Acn

Central Neurofibromatosis

Neurofibromatosis, Central Type

Acoustic Schwannomas, Bilateral

Acoustic Neurinoma, Bilateral

Bilateral Acoustic Neurinoma

Bilateral Acoustic Schwannomas

Familial Acoustic Neuromas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03355 CTXN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CTXN3 VGNC VGNC:61278
Bos taurus CTXN3 VGNC VGNC:27827
Mus musculus CTXN3 MGD MGI:3642816
Rattus norvegicus CTXN3 RGD RGD:2300148
Canis familiaris CTXN3 VGNC VGNC:39724