CLEC1A - C-type lectin domain family 1 member A Gene

Homo sapiens

Also known as CLEC1; CLEC-1

Gene ID: 51267 | Gene type: protein coding

About CLEC1A

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,069,554-10,098,985 (from NCBI)

This gene has 5 transcripts (splice variants), 370 orthologues, 23 paralogues and is associated with 1 phenotype. Biased expression in placenta (RPKM 18.1), lung (RPKM 3.8) and 10 other tissues.

Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

CLEC1A Products(5)

mRNA	Protein	Name
NM_001297748.2	NP_001284677.1	C-type lectin domain family 1 member A isoform b
NM_001297749.2	NP_001284678.1	C-type lectin domain family 1 member A isoform c
NM_001297750.2	NP_001284679.1	C-type lectin domain family 1 member A isoform d
NM_001297751.2	NP_001284680.1	C-type lectin domain family 1 member A isoform d
NM_016511.4	NP_057595.2	C-type lectin domain family 1 member A isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLEC1A Protein Structure

Lectin_C

0
100
200
280 a.a.

Protein Preferred Names

Protein Names

C-type lectin domain family 1 member A

C-type lectin-like receptor-1

Recombinant CLEC1A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75338	CLEC-1/CLEC1A Protein, Human (HEK293, Fc)	Q8NC01/NP_057595.2 (Q77-D280)	≥95%

Related Diseases

Diseases

Alias

Aspergillosis

Aspergillosis, Susceptibility To	Infection Due To Aspergillus
Aspergilloma	Aspergillus Nodule
Simple Aspergilloma	Aspergillus
Aspergillus Flavus Infection	Aspergillus Fumigatus Infection
Aspergillus Infection	Infection By Aspergillus Fumigatus
Intracavitary Aspergillus Fungus Ball	Aspergillus Terreus

Glioblastoma Proneural Subtype

White Piedra

Tinea Blanca

Trichosporosis Nodosa

Autoimmune Atherosclerosis

Subcutaneous Mycosis

Subcutaneous Fungal Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02785	CLEC1A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CLEC1A	VGNC	VGNC:71335
Bos taurus	CLEC1A	VGNC	VGNC:27427
Mus musculus	CLEC1A	MGD	MGI:2444151
Rattus norvegicus	CLEC1A	RGD	RGD:1566110
Felis catus	CLEC1A	VGNC	VGNC:83534
Others	CLEC1A	NCBI

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