1. Gene
  2. PDGFB - platelet derived growth factor subunit B Gene

PDGFB - platelet derived growth factor subunit B Gene

Homo sapiens

Also known as SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2

Gene ID: 5155 | Gene type: protein coding

About PDGFB

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:39,223,359-39,244,982 (from NCBI)

This gene has 4 transcripts (splice variants), 263 orthologues, 1 paralogue and is associated with 66 phenotypes. Broad expression in placenta (RPKM 18.6), fat (RPKM 12.7) and 23 other tissues.

Summary

This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF Receptor Tyrosine Kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

PDGFB Products(2)

mRNA Protein Name
NM_002608.4 NP_002599.1 platelet-derived growth factor subunit B isoform 1 preproprotein
NM_033016.3 NP_148937.1 platelet-derived growth factor subunit B isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chemoattractant activity IDA
IDA: Inferred from direct assay
21245381 GOA
enables collagen binding IDA
IDA: Inferred from direct assay
8900172 GOA
enables growth factor activity IDA
IDA: Inferred from direct assay
12070119 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
1396586 GOA
enables platelet-derived growth factor binding IPI
IPI: Inferred from physical interaction
7073684 GOA
enables platelet-derived growth factor receptor binding EXP
EXP: Inferred from Experiment
20534510 GOA
enables platelet-derived growth factor receptor binding IDA
IDA: Inferred from direct assay
2439522 GOA
enables platelet-derived growth factor receptor binding IPI
IPI: Inferred from physical interaction
2536956 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
2536956 GOA
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
7073684 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
2836953 GOA
enables superoxide-generating NADPH oxidase activator activity IDA
IDA: Inferred from direct assay
17942966 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cell chemotaxis IDA
IDA: Inferred from direct assay
16014047 GOA
involved in cellular response to growth factor stimulus IDA
IDA: Inferred from direct assay
21245381 GOA
involved in gene expression IDA
IDA: Inferred from direct assay
16530387 GOA
NOT involved in hemopoiesis IMP
IMP: Inferred from mutant phenotype
11264163 GOA
involved in interleukin-18-mediated signaling pathway IDA
IDA: Inferred from direct assay
21321938 GOA
involved in intracellular signal transduction IMP
IMP: Inferred from mutant phenotype
24008408 GOA
involved in monocyte chemotaxis IDA
IDA: Inferred from direct assay
17991872 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
25089138 GOA
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
16530387 GOA
involved in negative regulation of miRNA transcription IDA
IDA: Inferred from direct assay
26493107 GOA
involved in negative regulation of phosphatidylinositol biosynthetic process IDA
IDA: Inferred from direct assay
2538439 GOA
involved in negative regulation of platelet activation IDA
IDA: Inferred from direct assay
2538439 GOA
involved in negative regulation of vascular associated smooth muscle cell differentiation IDA
IDA: Inferred from direct assay
19088079 GOA
involved in peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
10734101 GOA
involved in platelet-derived growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
2439522 GOA
involved in positive regulation of DNA biosynthetic process IDA
IDA: Inferred from direct assay
10644978 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
17324121 GOA
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
11788434 GOA
involved in positive regulation of MAP kinase activity IDA
IDA: Inferred from direct assay
9685360 GOA
involved in positive regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
11788434 GOA
involved in positive regulation of blood vessel endothelial cell migration IDA
IDA: Inferred from direct assay
9685360 GOA
involved in positive regulation of calcium ion import IDA
IDA: Inferred from direct assay
19019919 GOA
involved in positive regulation of cell migration IDA
IDA: Inferred from direct assay
11788434 GOA
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
2439522 GOA
involved in positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
19126672 GOA
involved in positive regulation of chemotaxis IDA
IDA: Inferred from direct assay
9409235 GOA
involved in positive regulation of endothelial cell proliferation IDA
IDA: Inferred from direct assay
9685360 GOA
involved in positive regulation of fibroblast proliferation IDA
IDA: Inferred from direct assay
2439522 GOA
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
23554459 GOA
involved in positive regulation of glomerular mesangial cell proliferation IDA
IDA: Inferred from direct assay
11788434 GOA
involved in positive regulation of hyaluronan biosynthetic process IDA
IDA: Inferred from direct assay
17324121 GOA
involved in positive regulation of metanephric mesenchymal cell migration IDA
IDA: Inferred from direct assay
10734101 GOA
involved in positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway IDA
IDA: Inferred from direct assay
19019919 GOA
involved in positive regulation of miRNA transcription IDA
IDA: Inferred from direct assay
19088079 GOA
involved in positive regulation of mitotic nuclear division IDA
IDA: Inferred from direct assay
10644978 GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
10734101 GOA
involved in positive regulation of protein autophosphorylation IDA
IDA: Inferred from direct assay
12070119 GOA
involved in positive regulation of reactive oxygen species metabolic process IDA
IDA: Inferred from direct assay
19019919 GOA
involved in positive regulation of smooth muscle cell migration IDA
IDA: Inferred from direct assay
9409235 GOA
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
21321938 GOA
involved in positive regulation of vascular associated smooth muscle cell dedifferentiation IDA
IDA: Inferred from direct assay
19088079 GOA
involved in positive regulation of vascular associated smooth muscle cell migration IDA
IDA: Inferred from direct assay
12070119 GOA
involved in positive regulation of vascular associated smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
12070119 GOA
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
17942966 GOA
involved in reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
17942966 GOA
involved in response to wounding IDA
IDA: Inferred from direct assay
2538439 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
291037 GOA
part of platelet-derived growth factor complex IPI
IPI: Inferred from physical interaction
7679113 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PDGFB Protein Structure

PDGF_N

PDGF_N: Platelet-derived growth factor, N terminal region (21 - 96)

PDGF

PDGF: PDGF/VEGF domain (97 - 180)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

platelet-derived growth factor subunit B

PDGF subunit B

Recombinant PDGFB Proteins

Cat. No. Product Name Accession Purity
HY-P7055 PDGF-BB Protein, Human P01127-1 (S82-T190) ≥95%
HY-P7055A PDGF-BB Protein, Human (P.pastoris) P01127 (S82-T190) ≥95%
HY-P7055G GMP PDGF-BB Protein, Human P01127 (S82-T190) ≥95%
HY-P73351 PDGF-BB Protein, Human (P.pastoris, His) P01127 (S82-T190) ≥95%
HY-P7055B PDGF-BB Protein, Human (His) P01127-1 (S82-T190) ≥95%

Related Diseases

Diseases Alias
Dermatofibrosarcoma Protuberans

DFSP

Dermatofibrosarcoma

Giant Cell Fibroblastoma

Metastatic Dermatofibrosarcoma Protuberans

Familial Dermatofibrosarcoma Protuberans

Darier-Ferrand Tumor

Darier-Hoffmann Tumor

Basal Ganglia Calcification, Idiopathic, 5

IBGC5

Calcification, Basal Ganglia, Idiopathic, Type 5

Meningioma, Familial

Meningioma

Familial Meningioma

Meningioma, Familial, Susceptibility To

Meningeal Neoplasm

Meningeal Neoplasms

Meningiomas

Meningioma, Nf2-Related, Somatic

Meningioma, Sis-Related

Meningothelial Cell Tumor

Neoplasm Of The Meninges

Primary Meningeal Tumor

Familial Multiple Meningioma

MNGMA

Meningioma, Benign, No Icd-O Subtype

Intracranial Meningioma

Meningothelial Cell Neoplasm

Supratentorial Meningioma

Primary Neoplasm Of Spinal Meninges

Benign Intracranial Meningioma

Benign Meningioma

Meningeal Tumours

Meningeal Sarcoma Of Unspecified Site

Meningothelial Sarcoma Of Unspecified Site

Basal Ganglia Calcification, Idiopathic, 1

Primary Familial Brain Calcification

Pfbc

Bspdc

Bilateral Striopallidodentate Calcinosis

Cerebrovascular Ferrocalcinosis

IBGC1

Familial Idiopathic Basal Ganglia Calcification

Idiopathic Basal Ganglia Calcification 1

Striopallidodentate Calcinosis, Bilateral

Striopallidodentate Calcinosis, Autosomal Dominant, Adult-Onset

Cerebral Calcification, Nonarteriosclerotic, Idiopathic, Adult-Onset

Ferrocalcinosis, Cerebrovascular

Fahr Disease, Familial, Formerly

Basal Ganglia Calcification, Idiopathic, 3, Formerly

Ibgc3, Formerly

Basal Ganglia Calcification, Idiopathic, 2, Formerly

Ibgc2, Formerly

Fibgc

Striopallidodentate Calcinosis

Idiopathic Basal Ganglia Calcification

Ferrocalcinosis Cerebro Vascular

Autosomal Dominant Adult-Onset Striopallidodentate Calcinosis

Familial Fahr Disease

Ibgc2

Ibgc3

Idiopathic Basal Ganglia Calcification 2

Idiopathic Basal Ganglia Calcification 3

Non-Arteriosclerotic, Idiopathic, Adult-Onset Cerebral Calcification

Basal Ganglia Calcification, Idiopathic

Calcification, Basal Ganglia, Idiopathic

Calcification, Basal Ganglia, Idiopathic, Type 1

Fahr'S Syndrome

Basal Ganglia Calcification

Fahr'S Syndrome

Fahr'S Disease

Fahr Disease

Sarcoma

Connective And Soft Tissue Neoplasm

Tumor Of Soft Tissue And Skeleton

Sarcomas

Sarcoma - Category

Gingival Overgrowth

Gingival Enlargement

Gingival Hyperplasia

Gingival Bulge

Gingival Enlargement Nos

Gingival Hypertrophy

Gum Hypertrophy

Hyperplasia Gum

Gingival Thickening

Hyperplasia Of Gingiva

Hypertrophy Of Gingiva

Hypertrophy Of Mucous Membrane Of Gums

Cutaneous Fibrous Histiocytoma

Dermatofibroma

Fibrohistiocytic Tumor

Benign Cutaneous Fibrous Histiocytoma

Fibrous Histiocytoma Of Skin

Fibrous Xanthoma Of Skin

Pleomorphic Fibroma

Sclerosing Angioma

Sclerosing Angioma Of Skin

Fibrous Histiocytoma

Bronchiolitis Obliterans

Bronchiolitis Fibrosa Obliterans

Obliterative Bronchiolitis

Bronchiolitis Exudativa

Bronchiolitis, Exudative

Chronic Ulcer Of Skin

Chronic Wounds

Callous Ulcer

Indolent Ulcer

Chronic Ulcer

Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma

Retinal Detachment

Retinal Detachments

Rhegmatogenous Retinal Detachment

Ruptured Retina With Detachment

Retinal Hole With Detachment

Skin Sarcoma

Cutaneous Sarcoma

Arteriosclerosis

Arteriosclerotic Vascular Disease

Pulmonary Fibrosis

Fibrosis Of Lung

Glomerulonephritis

Bright'S Disease

Decubitus Ulcer

Pressure Ulcer

Pressure Sores

Pressure Ulcers

Bedsore

Decubitus Ulcer

Decubitus Ulcer Any Site

Oligodendroglioma

Oligodendroglial Neoplasm

Oligodendroglial Tumor

Oligodendroglial Tumors

Well Differentiated Oligodendroglioma

Costello Syndrome

Faciocutaneoskeletal Syndrome

Fcs Syndrome

Congenital Myopathy With Excess Of Muscle Spindles

CSTLO

CMEMS

Fcss

Myopathy, Congenital, With Excess Of Muscle Spindles

Glioma
Dementia

Dementias

Presenile Dementia

Alzheimer Type Dementia

Alzheimer Sclerosis

Alzheimer Disease Dementia

Alzheimer Dementia

Primary Degenerative Alzheimer Type Dementia

End Stage Alzheimer'S Dementia

Alzheimer'S Type Atypical Dementia

Alzheimer Type Presenile Dementia

Early Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 2

Dementia In Alzheimer Disease With Early Onset

Early Onset Alzheimer Type Dementia, Uncomplicated

Primary Degenerative Alzheimer Type Dementia, Early Onset

Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated

Alzheimer Disease Dementia With Early Onset

Presenile Sclerosis

Presenile Brain Sclerosis

Presenile Alzheimer Brain Sclerosis

Late Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 1

Dementia In Alzheimer Disease With Late Onset

Primary Degenerative Alzheimer Type Dementia, Late Onset

Sdat - [Senile Dementia, Alzheimer Type]

Alzheimer Disease Dementia With Late Onset

Late Onset Alzheimer Brain Sclerosis

Senile Alzheimer Brain Disease

Senile Alzheimer Brain Sclerosis

Senile Primary Degenerative Alzheimer Type Dementia

Senile Dementia Of The Alzheimer Type

Arteriosclerotic Dementia

Strategic-Infarct Dementia

Post Stroke Dementia

Vascular Cognitive Impairment

Vascular Dementia

Dementia Of The Lewy Body Type

Dementia With Lewy Bodies

Sdlt - [Senile Dementia Of The Lewy Body Type]

Senile Dementia Of The Lewy Body Type

Alcohol-Related Dementia

Alcoholic Dementia Nos

Alcohol-Induced Dementia

Alcoholic Brain Syndrome

Chronic Alcoholic Brain Syndrome

Alcohol Dementia

Late Onset Alcoholic Psychosis

Residual And Late-Onset Alcohol-Induced Psychotic Disorder

Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder

Late-Onset Psychoactive Substance-Induced Psychotic Disorder

Inhalant Dementia

Volatile Solvents Dementia

Dementia In Paralysis Agitans

Pdd - [Parkinson Disease Dementia]

Dementia Syndrome Of Parkinson Disease

Dementia In Parkinson Disease

Parkinson Related Dementia

Dementia In Huntington Chorea

Hiv - [Human Immunodeficiency Virus] Dementia

Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex

Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex

Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex

Aids Related Dementia

Dementia Due To Niacin Deficiency

Desmoid Tumor

Aggressive Fibromatosis

Desmoid Type Fibromatosis

Familial Infiltrative Fibromatosis

Desmoid Disorder, Hereditary

Fif

Fibromatosis, Familial Infiltrative

Deep Fibromatosis

Desmoid Fibromatosis

Hereditary Desmoid Disease

Musculoaponeurotic Fibromatosis

Desmoid-Type Fibromatosis

Fibromatosis, Aggressive

Desmoid Disease, Hereditary

Musculo-Aponeurotic Fibromatosis

Crouzon Syndrome With Acanthosis Nigricans

Crouzon Syndrome-Acanthosis Nigricans Syndrome

CAN

Crouzonodermoskeletal Syndrome

Crouzon-Dermoskeletal Syndrome

Crouzon, With Acanthosis Nigricans Syndrome

Dystonia

Dystonic Disease

Dystonic Disorder

Dystonia Disorders

Neuroleptic Dyskinesia

Renal Fibrosis
Hemangioma

Hemangiomas

Fibrosarcoma

Neoplasms, Fibrous Tissue

Fibrocytic Tumor

Fibrosarcoma Of Soft Tissue

Fibrous Tissue Neoplasm

Basal Ganglia Disease

Basal Ganglia Diseases

Basal Ganglia Disorders

Abnormality Of The Basal Ganglia

Essential Thrombocythemia

Essential Thrombocytosis

Familial Thrombocytosis

Hemorrhagic Thrombocythemia

Hereditary Thrombocythemia

Primary Thrombocytosis

Idiopathic Thrombocythemia

Primary Thrombocythemia

Thrombocythemia, Essential

Essential Thrombocythaemia

Et

Familial Thrombocythemia

Thrombocythemia Essential

Ewing Sarcoma

Neuroepithelioma

Ewing'S Tumor

Primitive Neuroectodermal Tumor

Ewings Sarcoma

Ewing'S Sarcoma

Peripheral Neuroepithelioma

ES

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Localized Peripheral Primitive Neuroectodermal Tumor

Peripheral Primitive Neuroectodermal Tumor

Ewing Tumor

Sarcoma, Ewing'S

Ewing Family Of Tumors

Extraosseous Ewing Tumor

Askin Tumor

Ewing'S Family Localized Tumor

Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing Sarcoma

Localized Ewing'S Sarcoma

Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing'S Tumor

Pnet Of Thoracopulmonary Region

Tumor Of The Ewing Family

Skeletal Ewing Sarcoma

Osseous Ewing Sarcoma

Ppnet

Peripheral Pnet

Extraskeletal Ewing Sarcoma

Eoe

Extraosseous Ewing Sarcoma

Extraskeletal Ewing Tumor

Esft

Ewing Sarcoma Family Of Tumors

Pne

Pnet

Pnet Of The Chest Wall

Sarcoma, Ewing

Neuroectodermal Tumors, Primitive, Peripheral

Neuroectodermal Tumor, Primitive

Disorder Of Eye

Askin'S Tumor

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Neuroepithelioma, Peripheral

Asbestos-Related Lung Carcinoma
Langerhans Cell Histiocytosis

Histiocytosis X

Lch

Langerhans Cell Granulomatosis

Langerhans-Cell Histiocytosis

Letterer-Siwe Disease

Hashimoto-Pritzger Disease

Histiocytosis, Langerhans-Cell

Langerhan'S Cell Histiocytosis

Letterer-Siwe Disease Involving Intra-Abdominal Lymph Nodes

Letterer-Siwe Disease Involving Intrapelvic Lymph Nodes

Letterer-Siwe Disease Involving Intrathoracic Lymph Nodes

Letterer-Siwe Disease Involving Lymph Nodes Of Axilla And Upper Limb

Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face And Neck

Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face, And Neck

Letterer-Siwe Disease Involving Lymph Nodes Of Inguinal Region And Lower Limb

Letterer-Siwe Disease Involving Lymph Nodes Of Multiple Sites

Letterer-Siwe Disease Involving Spleen

Letterer-Siwe Disease Of Intra-Abdominal Lymph Nodes

Letterer-Siwe Disease Of Intrapelvic Lymph Nodes

Letterer-Siwe Disease Of Intrathoracic Lymph Nodes

Letterer-Siwe Disease Of Lymph Nodes Of Axilla And Upper Limb

Letterer-Siwe Disease Of Lymph Nodes Of Axilla And/Or Upper Limb

Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And Neck

Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And/Or Neck

Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region Amd/Or Lower Limb

Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And Lower Limb

Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb

Letterer-Siwe Disease Of Lymph Nodes Of Multiple Sites

Letterer-Siwe Disease Of Spleen

Familial Letterer-Siwe Disease

Langerhans-Cell Histiocytosis Nos

Infantile Myofibromatosis

Lipofibromatosis

Myofibromatosis

Interstitial Lung Disease 2

Idiopathic Pulmonary Fibrosis

Ipf

Fibrocystic Pulmonary Dysplasia

Pulmonary Fibrosis, Idiopathic

Pulmonary Fibrosis, Idiopathic, Susceptibility To

Cryptogenic Fibrosing Alveolitis

ILD2

Idiopathic Pulmonary Fibrosis, Familial

Fibrosing Alveolitis, Cryptogenic

Uip

Fibrosing Alveolitis

Interstitial Pneumonitis, Usual

Familial Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis, Chronic Form

Usual Interstitial Pneumonia

Fibrosing Alveolitis Cryptogenic

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis Familial

Interstitial Pneumonitis Usual

Fibrosis Idiopathic Pulmonary

Fibrosis, Pulmonary, Idiopathic

Hamman-Rich Syndrome

Chronic Idiopathic Pulmonary Fibrosis

Acute Interstitial Pneumonia

Interstitial Pulmonary Fibrosis

Ipf - [Idiopathic Pulmonary Fibrosis]

Idiopathic Lung Fibrosis

Fibrosing Lung Disease

Pulmonary Fibrosis Nos

Fibrosing Pneumonitis

Pulmonary Plasma Cell Granuloma

Plasma Cell Granuloma, Pulmonary

Granuloma, Plasma Cell, Pulmonary

Lymphocytic Pseudotumor Of Lung

Sclerosing Hemangiocytoma Of Lung

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Rhabdomyosarcoma
Iga Glomerulonephritis

Iga Nephropathy

Glomerulonephritis, Iga

Berger'S Iga Or Igg Nephropathy

Focal Glomerulonephritis

Primary Iga Nephropathy

Segmental Glomerulonephritis

Berger Disease

Berger'S Disease

Igan

Nephritis, Iga Type

Nephropathy Iga

Glomerulonephritis Focal

Iga Nephropathy, Susceptibility To

Primary Immunoglobulin A Nephropathy

Microvascular Complications Of Diabetes 5

Diabetic Retinopathy

Microvascular Complications Of Diabetes, Susceptibility To, 5

MVCD5

Retinopathy, Diabetic

Diabetic Nephropathy

Retinopathy, Diabetic, Susceptibility To

Retinal Abnormality - Diabetes-Related

Familiar Ovarian Carcinoma
Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Diffuse Midline Glioma, H3 K27m-Mutant

Diffuse Intrinsic Pontine Glioma

Dipg

Infiltrative Brainstem Glioma

Bronchiectasis 2
Sexual Sadism

Sadism

Exudative Vitreoretinopathy 1

Retinopathy Of Prematurity

Retrolental Fibroplasia

EVR1

Criswick-Schepens Syndrome

Rop

Exudative Vitreoretinopathy, Familial, Autosomal Dominant

Fevr, Autosomal Dominant

Premature Retinopathy

Vitreoretinopathy, Exudative 1

Autosomal Dominant Familial Exudative Vitreoretinopathy

Fevr

Vitreoretinopathy, Exudative, Type 1

Retinopathy Of Prematurity Nos

Rlf- [Retrolental Fibroplasia]

Rop - [Retinopathy Of Prematurity]

Terry Syndrome

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Gastrointestinal Stromal Tumor

GIST

Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Sarcoma

Gastrointestinal Stromal Tumor, Familial

Gant

Gastrointestinal Stromal Tumour

Stromal Tumor Of Gastrointestinal Tract

Stromal Tumour Of Gastrointestinal Tract

Gastrointestinal Stromal Neoplasm

Paraganglioma And Gastric Stromal Sarcoma

Plexosarcoma

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus PDGFB MGD MGI:97528
Rattus norvegicus PDGFB RGD RGD:3283
Macaca mulatta PDGFB VGNC VGNC:75927
Felis catus PDGFB VGNC VGNC:68770
Canis familiaris PDGFB VGNC VGNC:44369
Bos taurus PDGFB VGNC VGNC:32690
Macaca fascicularis PDGFB NCBI NCBI:102125183
Others PDGFB NCBI