YPEL5 - yippee like 5 Gene

Homo sapiens

Also known as CGI-127

Gene ID: 51646 | Gene type: protein coding

About YPEL5

Cytogenetic location: 2p23.1 Genomic coordinates (GRCh38): 2:30,147,007-30,160,533 (from NCBI)

This gene has 10 transcripts (splice variants), 279 orthologues and 10 paralogues. Ubiquitous expression in bone marrow (RPKM 117.0), testis (RPKM 35.1) and 24 other tissues.

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in cell population proliferation. Part of ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

YPEL5 Products(4)

mRNA	Protein	Name
NM_001127399.2	NP_001120871.1	protein yippee-like 5
NM_001127400.2	NP_001120872.1	protein yippee-like 5
NM_001127401.2	NP_001120873.1	protein yippee-like 5
NM_016061.3	NP_057145.1	protein yippee-like 5

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20580816	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of ubiquitin ligase complex	IDA IDA: Inferred from direct assay	29911972	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

YPEL5 Protein Structure

Yippee-Mis18

0
100
121 a.a.

Protein Preferred Names

Protein Names

protein yippee-like 5

YPEL5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	YPEL5	P62699	GSC2	Homo sapiens	O15499	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	GSC2	Homo sapiens	O15499	Y2H Array	32296183
Intra	YPEL5	P62699	PLAGL2	Homo sapiens	Q9UPG8	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	PLAGL2	Homo sapiens	Q9UPG8	Validated Y2H	32296183
Intra	YPEL5	P62699	PLAGL2	Homo sapiens	Q9UPG8	Y2H Array	32296183
Intra	YPEL5	P62699	PFDN5	Homo sapiens	Q99471	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	PFDN5	Homo sapiens	Q99471	Validated Y2H	32296183
Intra	YPEL5	P62699	PFDN5	Homo sapiens	Q99471	Y2H Array	32296183
Intra	YPEL5	P62699	PSMA1	Homo sapiens	P25786	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	PSMA1	Homo sapiens	P25786	Y2H Array	32296183
Intra	YPEL5	P62699	TRAF5	Homo sapiens	O00463	Y2H Array	32296183
Intra	YPEL5	P62699	TRAF5	Homo sapiens	O00463	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	ZNF655	Homo sapiens	Q8N720	Validated Y2H	32296183
Intra	YPEL5	P62699	ZNF655	Homo sapiens	Q8N720	Y2H Array	32296183
Intra	YPEL5	P62699	ZNF655	Homo sapiens	Q8N720	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	DDIT4L	Homo sapiens	Q96D03	Validated Y2H	32296183
Intra	YPEL5	P62699	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	YPEL5	P62699	CTDSP1	Homo sapiens	Q9GZU7	Y2H Prey Pooling	32296183
Intra	YPEL5	P62699	CTDSP1	Homo sapiens	Q9GZU7	Validated Y2H	32296183
Intra	YPEL5	P62699	CTDSP1	Homo sapiens	Q9GZU7	Y2H Array	32296183
Intra	YPEL5	P62699	SHC3	Homo sapiens	Q92529	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15933	YPEL5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	YPEL5	RGD	RGD:1309657
Canis familiaris	YPEL5	VGNC	VGNC:48501
Felis catus	YPEL5	VGNC	VGNC:67149
Macaca mulatta	YPEL5	VGNC	VGNC:79128
Bos taurus	YPEL5	VGNC	VGNC:37037
Mus musculus	YPEL5	MGD	MGI:1916937

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