Rassf5 - Ras association (RalGDS/AF-6) domain family member 5 Gene

Mus musculus

Also known as Rapl; Maxp1; Nore1; Nore1A; Nore1B; 1300019G20Rik

Gene ID: 54354 | Gene type: protein coding

About Rassf5

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of protein ubiquitination; and regulation of protein localization to nucleus. Located in nucleus. Is expressed in heart and thymus primordium. Used to study systemic lupus erythematosus. Orthologous to human RASSF5 (Ras association domain family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Rassf5 Products(3)

mRNA	Protein	Name
NM_001311094.2	NP_001298023.1	ras association domain-containing protein 5 isoform 2
NM_001313731.1	NP_001300660.1	ras association domain-containing protein 5 isoform 3
NM_018750.4	NP_061220.2	ras association domain-containing protein 5 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	9488663	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of lymphocyte proliferation	IMP IMP: Inferred from mutant phenotype	21194982	MGI
acts upstream of or within negative regulation of lymphocyte proliferation	IMP IMP: Inferred from mutant phenotype	21194982	MGI
acts upstream of or within positive regulation of protein ubiquitination	IMP IMP: Inferred from mutant phenotype	22173032	MGI
acts upstream of or within regulation of protein localization to nucleus	IMP IMP: Inferred from mutant phenotype	21194982	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	22173032	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ras association domain-containing protein 5

Rap1-binding protein	new ras effector 1
novel ras effector 1	regulator for cell adhesion and polarization enriched in lymphoid tissues

Rassf5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Rassf5	Q5EBH1	Stk4	Mus musculus	Q9JI11	Anti Bait CoIP	16892067
Cross	Rassf5	Q5EBH1	HRAS	Homo sapiens	P01112	NMR	16698549
Cross	Rassf5	Q5EBH1	HRAS	Homo sapiens	P01112	Fluorescence	18596699
Cross	Rassf5	Q5EBH1	HRAS	Homo sapiens	P01112	ITC	16698549
Cross	Rassf5	Q5EBH1	HRAS	Homo sapiens	P01112	X-Ray Diffraction	18596699
Intra	Rassf5	Q5EBH1	Hras	Mus musculus	Q61411	Pull Down	9488663
Cross	Rassf5	Q5EBH1	RAP1A	Homo sapiens	P62834	ITC	16698549
Cross	Rassf5	Q5EBH1	RAP1A	Homo sapiens	P62834	Anti Tag CoIP	12845325
Intra	Rassf5	Q5EBH1	Mdm2	Mus musculus	P23804	Y2H	22173032
Intra	Rassf5	Q5EBH1	Hipk1	Mus musculus	O88904	Y2H	22173032

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11705	RASSF5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rassf5	NCBI	NCBI:83593

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