STRBP - spermatid perinuclear RNA binding protein Gene

Homo sapiens

Also known as p74; SPNR; ILF3L; HEL162

Gene ID: 55342 | Gene type: protein coding

About STRBP

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:123,109,494-123,268,586 (from NCBI)

This gene has 10 transcripts (splice variants), 281 orthologues and 14 paralogues. Broad expression in testis (RPKM 6.5), lymph node (RPKM 4.6) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within mechanosensory behavior and spermatid development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

STRBP Products(5)

mRNA	Protein	Name
NM_001171137.2	NP_001164608.1	spermatid perinuclear RNA-binding protein isoform 2
NM_001376106.1	NP_001363035.1	spermatid perinuclear RNA-binding protein isoform 1
NM_001376107.1	NP_001363036.1	spermatid perinuclear RNA-binding protein isoform 1
NM_001376109.1	NP_001363038.1	spermatid perinuclear RNA-binding protein isoform 3
NM_018387.5	NP_060857.2	spermatid perinuclear RNA-binding protein isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STRBP Protein Structure

DZF

dsrm

0
200
400
600
672 a.a.

Protein Preferred Names

Protein Names

spermatid perinuclear RNA-binding protein

epididymis luminal protein 162

STRBP Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	STRBP	Q96SI9	ZMAT4	Homo sapiens	Q9H898-2	Y2H Prey Pooling	26871637
Intra	STRBP	Q96SI9	ZMAT4	Homo sapiens	Q9H898-2	Validated Y2H	26871637
Intra	STRBP	Q96SI9	ZMAT4	Homo sapiens	Q9H898-2	Y2H Array	26871637
Intra	STRBP	Q96SI9	RBPMS2	Homo sapiens	Q6ZRY4	Y2H Array	32296183
Intra	STRBP	Q96SI9	RBPMS2	Homo sapiens	Q6ZRY4	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	ADARB1	Homo sapiens	P78563-4	Y2H Array	32296183
Intra	STRBP	Q96SI9	ADARB1	Homo sapiens	P78563-4	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	CAMK2G	Homo sapiens	Q13555-5	Y2H Array	32296183
Intra	STRBP	Q96SI9	CAMK2G	Homo sapiens	Q13555-5	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	RBFOX1	Homo sapiens	Q9NWB1-5	Validated Y2H	26871637
Intra	STRBP	Q96SI9	RBFOX1	Homo sapiens	Q9NWB1-5	Y2H Array	26871637
Intra	STRBP	Q96SI9	RBFOX1	Homo sapiens	Q9NWB1-5	Y2H Prey Pooling	26871637
Intra	STRBP	Q96SI9	ZNF346	Homo sapiens	Q9UL40	Validated Y2H	32296183
Intra	STRBP	Q96SI9	ZNF346	Homo sapiens	Q9UL40	Y2H Array	32296183
Intra	STRBP	Q96SI9	ZNF346	Homo sapiens	Q9UL40	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	STAU1	Homo sapiens	O95793	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	STAU1	Homo sapiens	O95793	Y2H Array	32296183
Intra	STRBP	Q96SI9	PRKRA	Homo sapiens	O75569	Anti Tag CoIP	33961781
Intra	STRBP	Q96SI9	PRKRA	Homo sapiens	O75569	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	PRKRA	Homo sapiens	O75569	Y2H Array	32296183
Intra	STRBP	Q96SI9	HMGXB4	Homo sapiens	Q9UGU5	Y2H Array	32296183
Intra	STRBP	Q96SI9	HMGXB4	Homo sapiens	Q9UGU5	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	HMGXB4	Homo sapiens	Q9UGU5	Validated Y2H	32296183
Intra	STRBP	Q96SI9	RBPMS	Homo sapiens	Q93062	Y2H Prey Pooling	25416956
Intra	STRBP	Q96SI9	RBPMS	Homo sapiens	Q93062	Validated Y2H	25416956
Intra	STRBP	Q96SI9	RBPMS	Homo sapiens	Q93062	Y2H Array	25416956
Intra	STRBP	Q96SI9	RBPMS	Homo sapiens	Q93062-3	Y2H Prey Pooling	26871637
Intra	STRBP	Q96SI9	RBPMS	Homo sapiens	Q93062-3	Validated Y2H	26871637
Intra	STRBP	Q96SI9	RBPMS	Homo sapiens	Q93062-3	Y2H Array	26871637
Intra	STRBP	Q96SI9	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	32296183
Intra	STRBP	Q96SI9	THAP1	Homo sapiens	Q9NVV9	Validated Y2H	32296183
Intra	STRBP	Q96SI9	THAP1	Homo sapiens	Q9NVV9	Y2H Array	25416956
Intra	STRBP	Q96SI9	THAP1	Homo sapiens	Q9NVV9	Y2H Array	32296183
Intra	STRBP	Q96SI9	DAB1	Homo sapiens	O75553	Validated Y2H	25416956
Intra	STRBP	Q96SI9	TARBP2	Homo sapiens	Q15633	Anti Tag CoIP	33961781
Intra	STRBP	Q96SI9	TARBP2	Homo sapiens	Q15633	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13962	STRBP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	STRBP	RGD	RGD:620673
Bos taurus	STRBP	VGNC	VGNC:35421
Macaca mulatta	STRBP	VGNC	VGNC:78136
Mus musculus	STRBP	MGD	MGI:104626
Canis familiaris	STRBP	VGNC	VGNC:46942

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