UBAP2 - ubiquitin associated protein 2 Gene

Homo sapiens

Also known as UBAP-2

Gene ID: 55833 | Gene type: protein coding

About UBAP2

This gene has 27 transcripts (splice variants), 294 orthologues and 1 paralogue. Broad expression in testis (RPKM 18.9), adrenal (RPKM 7.6) and 25 other tissues.

Summary

The protein encoded by this gene contains a UBA (ubiquitin associated) domain, which is characteristic of proteins that function in the ubiquitination pathway. This gene may show increased expression in the adrenal gland and lymphatic tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

UBAP2 Products(9)

mRNA	Protein	Name
NM_001282530.2	NP_001269459.1	ubiquitin-associated protein 2 isoform 5
NM_001370059.2	NP_001356988.2	ubiquitin-associated protein 2 isoform 1
NM_001370062.2	NP_001356991.2	ubiquitin-associated protein 2 isoform 1
NM_001370064.2	NP_001356993.2	ubiquitin-associated protein 2 isoform 8
NM_001370066.2	NP_001356995.2	ubiquitin-associated protein 2 isoform 6
NM_001370067.2	NP_001356996.2	ubiquitin-associated protein 2 isoform 7
NM_001370068.2	NP_001356997.2	ubiquitin-associated protein 2 isoform 6
NM_018449.4	NP_060919.4	ubiquitin-associated protein 2 isoform 1
NM_020867.2	NP_065918.1	ubiquitin-associated protein 2 isoform 7

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UBAP2 Protein Structure

UBA

DUF3697

0
200
400
600
800
1000
1119 a.a.

Protein Preferred Names

Protein Names

ubiquitin-associated protein 2

AD-012 protein

UBAP2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	UBAP2	Q5T6F2	BANP	Homo sapiens	Q8N9N5-2	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	ATPAF2	Homo sapiens	Q8N5M1	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	IGFN1	Homo sapiens	Q86VF2-5	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	SPAG8	Homo sapiens	Q99932-2	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	KRTAP15-1	Homo sapiens	Q3LI76	Y2H Prey Pooling	32296183
Intra	UBAP2	Q5T6F2	KRTAP15-1	Homo sapiens	Q3LI76	Y2H Array	32296183
Intra	UBAP2	Q5T6F2	ASB13	Homo sapiens	Q8WXK3-2	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	NOXA1	Homo sapiens	Q86UR1-2	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	C10orf55	Homo sapiens	Q5SWW7	Y2H Prey Pooling	32296183
Intra	UBAP2	Q5T6F2	C10orf55	Homo sapiens	Q5SWW7	Y2H Array	32296183
Intra	UBAP2	Q5T6F2	CREM	Homo sapiens	Q03060-25	Y2H Prey Pooling	32296183
Intra	UBAP2	Q5T6F2	CREM	Homo sapiens	Q03060-25	Y2H Array	32296183
Intra	UBAP2	Q5T6F2	KANK2	Homo sapiens	Q63ZY3	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	WRAP53	Homo sapiens	Q9BUR4	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	TFG	Homo sapiens	Q92734	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	RHOXF2	Homo sapiens	Q9BQY4	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	PLEKHB2	Homo sapiens	Q96CS7	Y2H Prey Pooling	32296183
Intra	UBAP2	Q5T6F2	PLEKHB2	Homo sapiens	Q96CS7	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	PLEKHB2	Homo sapiens	Q96CS7	Y2H Array	32296183
Intra	UBAP2	Q5T6F2	NPAS2	Homo sapiens	Q99743	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	DAZAP2	Homo sapiens	Q15038	Y2H Prey Pooling	32296183
Intra	UBAP2	Q5T6F2	DAZAP2	Homo sapiens	Q15038	Y2H Array	32296183
Intra	UBAP2	Q5T6F2	RBPMS	Homo sapiens	Q93062-3	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	OTX1	Homo sapiens	P32242	Y2H Prey Pooling	32296183
Intra	UBAP2	Q5T6F2	SPMIP9	Homo sapiens	Q96LM6	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	q96ej4_human	Homo sapiens	Q96EJ4	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	TENT5B	Homo sapiens	Q96A09	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	SHC3	Homo sapiens	Q92529	Validated Y2H	32296183
Intra	UBAP2	Q5T6F2	TEP1	Homo sapiens	Q99973	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15329	UBAP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15330	UBAP2L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	UBAP2	VGNC	VGNC:78949
Bos taurus	UBAP2	VGNC	VGNC:36572
Rattus norvegicus	UBAP2	RGD	RGD:1311717
Canis familiaris	UBAP2	VGNC	VGNC:48046
Felis catus	UBAP2	VGNC	VGNC:66753
Mus musculus	UBAP2	MGD	MGI:1916176

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