CTTNBP2NL - CTTNBP2 N-terminal like Gene

Homo sapiens

Gene ID: 55917 | Gene type: protein coding

About CTTNBP2NL

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,391,087-112,461,164 (from NCBI)

This gene has 4 transcripts (splice variants), 270 orthologues and 3 paralogues. Ubiquitous expression in esophagus (RPKM 9.4), gall bladder (RPKM 9.0) and 23 other tissues.

Summary

Enables protein Phosphatase 2A binding activity. Acts upstream of or within negative regulation of transmembrane transport; negative regulation of transporter activity; and protein dephosphorylation. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

CTTNBP2NL Products(1)

mRNA	Protein	Name
NM_018704.3	NP_061174.1	CTTNBP2 N-terminal-like protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18782753	GOA
enables protein phosphatase 2A binding	IDA IDA: Inferred from direct assay	24218568	GOA

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of transmembrane transport	IMP IMP: Inferred from mutant phenotype	24218568	GOA
acts upstream of or within negative regulation of transporter activity	IMP IMP: Inferred from mutant phenotype	24218568	GOA
acts upstream of or within protein dephosphorylation	IMP IMP: Inferred from mutant phenotype	24218568	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of FAR/SIN/STRIPAK complex	IDA IDA: Inferred from direct assay	18782753	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CTTNBP2NL Protein Structure

CortBP2

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300
400
500
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639 a.a.

Protein Preferred Names

Protein Names

CTTNBP2 N-terminal-like protein

CTTNBP2NL Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CTTNBP2NL	Q9P2B4	STRN	Homo sapiens	O43815	BioID	24255178
Intra	CTTNBP2NL	Q9P2B4	STRN	Homo sapiens	O43815	Anti Tag CoIP	18782753
Intra	CTTNBP2NL	Q9P2B4	STRN3	Homo sapiens	Q13033	Anti Tag CoIP	18782753
Intra	CTTNBP2NL	Q9P2B4	STRN3	Homo sapiens	Q13033	BioID	24255178
Intra	CTTNBP2NL	Q9P2B4	STRIP1	Homo sapiens	Q5VSL9	Anti Tag CoIP	18782753
Intra	CTTNBP2NL	Q9P2B4	STRIP1	Homo sapiens	Q5VSL9	BioID	24255178
Intra	CTTNBP2NL	Q9P2B4	PKNOX2	Homo sapiens	Q96KN3	Y2H Array	32296183
Intra	CTTNBP2NL	Q9P2B4	PKNOX2	Homo sapiens	Q96KN3	Y2H Prey Pooling	32296183
Intra	CTTNBP2NL	Q9P2B4	STK26	Homo sapiens	Q9P289	Anti Tag CoIP	18782753
Intra	CTTNBP2NL	Q9P2B4	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
Intra	CTTNBP2NL	Q9P2B4	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
Intra	CTTNBP2NL	Q9P2B4	MOB4	Homo sapiens	Q9Y3A3	BioID	24255178
Intra	CTTNBP2NL	Q9P2B4	MOB4	Homo sapiens	Q9Y3A3	Anti Tag CoIP	18782753
Intra	CTTNBP2NL	Q9P2B4	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	25416956
Intra	CTTNBP2NL	Q9P2B4	STK24	Homo sapiens	Q9Y6E0	Anti Tag CoIP	18782753
Intra	CTTNBP2NL	Q9P2B4	HGS	Homo sapiens	O14964	Validated Y2H	25416956
Intra	CTTNBP2NL	Q9P2B4	HGS	Homo sapiens	O14964	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03352	CTTNBP2NL Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CTTNBP2NL	VGNC	VGNC:39720
Bos taurus	CTTNBP2NL	VGNC	VGNC:27823
Mus musculus	CTTNBP2NL	MGD	MGI:1933137
Macaca mulatta	CTTNBP2NL	VGNC	VGNC:71557
Rattus norvegicus	CTTNBP2NL	RGD	RGD:1310822
Felis catus	CTTNBP2NL	VGNC	VGNC:61275

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