2. Gene
  3. BCL2L14 - BCL2 like 14 Gene

BCL2L14 - BCL2 like 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BCLG

Gene ID: 79370 | Gene type: protein coding

About BCL2L14

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:12,049,861-12,099,695 (from NCBI)

This gene has 14 transcripts (splice variants), 1 gene allele, 165 orthologues and 1 paralogue. Biased expression in testis (RPKM 9.1), duodenum (RPKM 7.7) and 10 other tissues.

Summary

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce Apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]

BCL2L14 Products(5)

mRNA Protein Name
NM_001370268.1 NP_001357197.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
NM_001370269.1 NP_001357198.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
NM_030766.2 NP_110393.1 apoptosis facilitator Bcl-2-like protein 14 isoform 2
NM_138722.2 NP_620048.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
NM_138723.2 NP_620049.1 apoptosis facilitator Bcl-2-like protein 14 isoform 1
Protein Preferred Names Protein Names

apoptosis facilitator Bcl-2-like protein 14

BCL2-like 14 (apoptosis facilitator)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149624 Bcl-2-IN-14 / Unkown
HY-RS01432 BCL2L14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus BCL2L14 MGD MGI:1914063
Canis familiaris BCL2L14 VGNC VGNC:38410
Bos taurus BCL2L14 VGNC VGNC:26448
Rattus norvegicus BCL2L14 RGD RGD:1562777
Felis catus BCL2L14 VGNC VGNC:60085
Macaca mulatta BCL2L14 VGNC VGNC:70083