UBTD1 - ubiquitin domain containing 1 Gene

Homo sapiens

Gene ID: 80019 | Gene type: protein coding

About UBTD1

Cytogenetic location: 10q24.1-q24.2 Genomic coordinates (GRCh38): 10:97,498,924-97,571,206 (from NCBI)

This gene has 1 transcript (splice variant), 264 orthologues and 1 paralogue. Broad expression in testis (RPKM 17.5), lung (RPKM 11.7) and 22 other tissues.

Summary

The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating Enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]

UBTD1 Products(1)

mRNA	Protein	Name
NM_024954.5	NP_079230.1	ubiquitin domain-containing protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UBTD1 Protein Structure

ubiquitin

0
100
200
227 a.a.

Protein Preferred Names

Protein Names

ubiquitin domain-containing protein 1

UBTD1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	UBTD1	Q9HAC8	TRIM39	Homo sapiens	Q9HCM9-2	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	TRIM39	Homo sapiens	Q9HCM9-2	Validated Y2H	32296183
Intra	UBTD1	Q9HAC8	TRIM39	Homo sapiens	Q9HCM9-2	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	TP53BP2	Homo sapiens	Q05BL1	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	TP53BP2	Homo sapiens	Q05BL1	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	MID1	Homo sapiens	O15344	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	MID1	Homo sapiens	O15344	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	UBE2D2	Homo sapiens	P62837	Anti Tag CoIP	33961781
Intra	UBTD1	Q9HAC8	UBE2D3	Homo sapiens	P61077	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	UBE2D3	Homo sapiens	P61077	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	RNF5	Homo sapiens	Q99942	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	RNF5	Homo sapiens	Q99942	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	TRAF6	Homo sapiens	Q9Y4K3	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	TRAF6	Homo sapiens	Q9Y4K3	Validated Y2H	32296183
Intra	UBTD1	Q9HAC8	TRAF6	Homo sapiens	Q9Y4K3	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	TRIM39	Homo sapiens	Q9HCM9	Validated Y2H	25416956
Intra	UBTD1	Q9HAC8	TRIM39	Homo sapiens	Q9HCM9	Y2H Array	25416956
Intra	UBTD1	Q9HAC8	WWP2	Homo sapiens	O00308	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	WWP2	Homo sapiens	O00308	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	UBE2D4	Homo sapiens	Q9Y2X8	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	UBE2D4	Homo sapiens	Q9Y2X8	Y2H	19549727
Intra	UBTD1	Q9HAC8	UBE2D4	Homo sapiens	Q9Y2X8	Validated Y2H	32296183
Intra	UBTD1	Q9HAC8	UBE2D4	Homo sapiens	Q9Y2X8	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Prey Pooling	25416956
Intra	UBTD1	Q9HAC8	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	MRFAP1L1	Homo sapiens	Q96HT8	Validated Y2H	25416956
Intra	UBTD1	Q9HAC8	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Array	25416956
Intra	UBTD1	Q9HAC8	TRIM50	Homo sapiens	Q86XT4	Y2H Prey Pooling	32296183
Intra	UBTD1	Q9HAC8	TRIM50	Homo sapiens	Q86XT4	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	MRFAP1	Homo sapiens	Q9Y605	Validated Y2H	32296183
Intra	UBTD1	Q9HAC8	MRFAP1	Homo sapiens	Q9Y605	Y2H Array	32296183
Intra	UBTD1	Q9HAC8	MRFAP1	Homo sapiens	Q9Y605	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15392	UBTD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	UBTD1	MGD	MGI:2385092
Rattus norvegicus	UBTD1	RGD	RGD:1308172
Canis familiaris	UBTD1	VGNC	VGNC:48093
Bos taurus	UBTD1	VGNC	VGNC:36620
Macaca mulatta	UBTD1	VGNC	VGNC:106114
Felis catus	UBTD1	VGNC	VGNC:66789

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