CCDC92 - coiled-coil domain containing 92 Gene

Homo sapiens

Gene ID: 80212 | Gene type: protein coding

About CCDC92

This gene has 9 transcripts (splice variants), 1 gene allele, 205 orthologues and 1 paralogue. Broad expression in brain (RPKM 20.8), testis (RPKM 19.4) and 25 other tissues.

Summary

Enables identical protein binding activity. Located in centriole; centrosome; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CCDC92 Products(6)

mRNA	Protein	Name
NM_001304957.2	NP_001291886.1	coiled-coil domain-containing protein 92 isoform 1
NM_001304958.2	NP_001291887.1	coiled-coil domain-containing protein 92 isoform 1
NM_001304959.2	NP_001291888.1	coiled-coil domain-containing protein 92 isoform 1
NM_001304960.2	NP_001291889.1	coiled-coil domain-containing protein 92 isoform 1
NM_001304961.2	NP_001291890.1	coiled-coil domain-containing protein 92 isoform 2
NM_025140.3	NP_079416.1	coiled-coil domain-containing protein 92 isoform 1

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	22458338	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in centriole	IDA IDA: Inferred from direct assay	22863007	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC92 Protein Structure

CCDC92

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

coiled-coil domain-containing protein 92

limkain beta 2

CCDC92 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CCDC92	Q53HC0	TP53BP2	Homo sapiens	Q13625-3	Y2H Prey Pooling	25416956
Intra	CCDC92	Q53HC0	TRIML2	Homo sapiens	Q8N7C3	Validated Y2H	32296183
Intra	CCDC92	Q53HC0	DISC1	Homo sapiens	Q9NRI5-2	Y2H Prey Pooling	32296183
Intra	CCDC92	Q53HC0	DISC1	Homo sapiens	Q9NRI5-2	Validated Y2H	32296183
Intra	CCDC92	Q53HC0	DISC1	Homo sapiens	Q9NRI5-2	Y2H Array	32296183
Intra	CCDC92	Q53HC0	CEP164	Homo sapiens	Q9UPV0	Confocal	22863007
Intra	CCDC92	Q53HC0	CEP164	Homo sapiens	Q9UPV0	Anti Tag CoIP	22863007
Intra	CCDC92	Q53HC0	CEP164	Homo sapiens	Q9UPV0	Pull Down	22863007
Intra	CCDC92	Q53HC0	FHL2	Homo sapiens	Q14192	Y2H Array	25416956
Intra	CCDC92	Q53HC0	FHL2	Homo sapiens	Q14192	Y2H Array	31515488
Intra	CCDC92	Q53HC0	TRIM27	Homo sapiens	P14373	Validated Y2H	25416956
Intra	CCDC92	Q53HC0	TRIM27	Homo sapiens	P14373	Y2H Array	25416956
Intra	CCDC92	Q53HC0	CCDC92	Homo sapiens	Q53HC0	Validated Y2H	32296183
Intra	CCDC92	Q53HC0	CCDC92	Homo sapiens	Q53HC0	Y2H Array	32296183
Intra	CCDC92	Q53HC0	CCDC92	Homo sapiens	Q53HC0	Y2H Prey Pooling	32296183
Intra	CCDC92	Q53HC0	CEP76	Homo sapiens	Q8TAP6	Y2H Prey Pooling	25416956
Intra	CCDC92	Q53HC0	CEP76	Homo sapiens	Q8TAP6	Validated Y2H	25416956
Cross	CCDC92	Q53HC0	tax	Human T-cell leukemia virus 1	P14079	MAPPIT	22458338

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Lipodystrophy, Familial Partial, Type 1

FPLD1	Familial Partial Lipodystrophy Type 1
Familial Partial Lipodystrophy, Kobberling Type	Lipodystrophy, Familial Partial, Kobberling Type
Familial Partial Lipodystrophy Kobberling Type	Familial Partial Lipodystrophy Type Köbberling
Familial Partial Lipodystrophy, Köbberling Type	Familial Partial Lipodystrophy, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02067	CCDC92 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CCDC92	RGD	RGD:1601131
Macaca mulatta	CCDC92	VGNC	VGNC:70906
Felis catus	CCDC92	VGNC	VGNC:60529
Bos taurus	CCDC92	VGNC	VGNC:26933
Mus musculus	CCDC92	MGD	MGI:106485
Canis familiaris	CCDC92	VGNC	VGNC:38873

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