THSD7B - thrombospondin type 1 domain containing 7B Gene

Homo sapiens

Gene ID: 80731 | Gene type: protein coding

About THSD7B

This gene has 4 transcripts (splice variants), 187 orthologues and 3 paralogues. Biased expression in fat (RPKM 1.4), thyroid (RPKM 0.5) and 11 other tissues.

Summary

Predicted to be involved in actin Cytoskeleton reorganization. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

THSD7B Products(1)

mRNA	Protein	Name
NM_001316349.2	NP_001303278.1	thrombospondin type-1 domain-containing protein 7B precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

THSD7B Protein Structure

TSP_1

0
300
600
900
1200
1500
1609 a.a.

Protein Preferred Names

Protein Names

thrombospondin type-1 domain-containing protein 7B

thrombospondin, type I, domain containing 7B

THSD7B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	THSD7B	Q9C0I4	SLC30A8	Homo sapiens	Q8IWU4	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	SLC30A8	Homo sapiens	Q8IWU4	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	SLC30A8	Homo sapiens	Q8IWU4	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	LYVE1	Homo sapiens	Q9Y5Y7	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	LYVE1	Homo sapiens	Q9Y5Y7	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	LYVE1	Homo sapiens	Q9Y5Y7	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	CISD2	Homo sapiens	Q8N5K1	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	CISD2	Homo sapiens	Q8N5K1	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	CISD2	Homo sapiens	Q8N5K1	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	ARL13B	Homo sapiens	Q3SXY8	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	KCNJ6	Homo sapiens	P48051	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	KCNJ6	Homo sapiens	P48051	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	KCNJ6	Homo sapiens	P48051	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	STOM	Homo sapiens	P27105	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	STOM	Homo sapiens	P27105	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	STOM	Homo sapiens	P27105	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	AQP6	Homo sapiens	Q13520	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	GPR152	Homo sapiens	Q8TDT2	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	GJA8	Homo sapiens	P48165	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	GJA8	Homo sapiens	P48165	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	GJA8	Homo sapiens	P48165	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	SPACA1	Homo sapiens	Q9HBV2	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	SPACA1	Homo sapiens	Q9HBV2	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	SPACA1	Homo sapiens	Q9HBV2	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	PIGP	Homo sapiens	P57054	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	PIGP	Homo sapiens	P57054	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	PIGP	Homo sapiens	P57054	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	GPR101	Homo sapiens	Q96P66	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	GPR101	Homo sapiens	Q96P66	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	GPR101	Homo sapiens	Q96P66	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	FAM209A	Homo sapiens	Q5JX71	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	FAM209A	Homo sapiens	Q5JX71	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	FAM209A	Homo sapiens	Q5JX71	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	SLC14A1	Homo sapiens	Q13336-2	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	SLC14A1	Homo sapiens	Q13336-2	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	SLC14A1	Homo sapiens	Q13336-2	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	GPR37L1	Homo sapiens	O60883	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	GPR37L1	Homo sapiens	O60883	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	GPR37L1	Homo sapiens	O60883	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	MFSD14B	Homo sapiens	Q5SR56	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	MFSD14B	Homo sapiens	Q5SR56	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	MFSD14B	Homo sapiens	Q5SR56	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	KIR3DL1	Homo sapiens	P43629	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	KIR3DL1	Homo sapiens	P43629	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	KIR3DL1	Homo sapiens	P43629	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	DARS2	Homo sapiens	Q6PI48	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	DARS2	Homo sapiens	Q6PI48	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	DARS2	Homo sapiens	Q6PI48	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	FKBP7	Homo sapiens	Q9Y680	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	FKBP7	Homo sapiens	Q9Y680	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	FKBP7	Homo sapiens	Q9Y680	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	MTIF3	Homo sapiens	Q9H2K0	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	MTIF3	Homo sapiens	Q9H2K0	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	MTIF3	Homo sapiens	Q9H2K0	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	PEX12	Homo sapiens	O00623	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	PEX12	Homo sapiens	O00623	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	PEX12	Homo sapiens	O00623	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	SYT2	Homo sapiens	Q8N9I0	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	SYT2	Homo sapiens	Q8N9I0	Y2H Array	32296183
Intra	THSD7B	Q9C0I4	SYT2	Homo sapiens	Q8N9I0	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	PLEKHO1	Homo sapiens	Q53GL0	Validated Y2H	32296183
Intra	THSD7B	Q9C0I4	PLEKHO1	Homo sapiens	Q53GL0	Y2H Prey Pooling	32296183
Intra	THSD7B	Q9C0I4	PLEKHO1	Homo sapiens	Q53GL0	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14506	THSD7B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	THSD7B	RGD	RGD:1306938
Felis catus	THSD7B	VGNC	VGNC:66177
Mus musculus	THSD7B	MGD	MGI:2443925
Bos taurus	THSD7B	VGNC	VGNC:35851
Macaca mulatta	THSD7B	VGNC	VGNC:99411

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