2. Gene
  3. Lat - linker for activation of T cells Gene

Lat - linker for activation of T cells Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81511 | Gene type: protein coding

About Lat

Summary

Predicted to enable protein kinase binding activity and signaling receptor complex adaptor activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; intracellular signal transduction; and positive regulation of protein kinase activity. Predicted to act upstream of or within gene expression and lymphocyte homeostasis. Predicted to be located in Golgi apparatus; cell-cell junction; and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of COP9 signalosome. Predicted to be active in immunological synapse. Human ortholog(s) of this gene implicated in immunodeficiency 52. Orthologous to human LAT (linker for activation of T cells). [provided by Alliance of Genome Resources, Apr 2022]

Lat Products(1)

mRNA Protein Name
NM_030853.1 NP_110480.1 linker for activation of T-cells family member 1
Protein Preferred Names Protein Names

linker for activation of T-cells family member 1

36 kDa phospho-tyrosine adapter protein

p36-38

pp36

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-16929 Latrunculin A Inhibitor ≥98.0% Phase 4
HY-164401 QBS10072S / Phase 2
Pre-clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138489 TRULI Modulator 99.98% Unkown
HY-150042 TDI-011536 Inhibitor 99.91% Unkown
HY-108540 BCH Inducer 99.13% Unkown
HY-147082 GA-017 Activator 98.95% Unkown
HY-W011391 GPNA hydrochloride 99.91% Unkown
HY-139330 MGH-CP1 Inducer 99.56% Unkown
HY-160769 NIBR-LTSi Activator 99.97% Unkown
HY-147165 VT02956 Inhibitor 99.58% Unkown
HY-120139 KMH-233 Inhibitor 98.11% Unkown
HY-N8847 α-Ionone Activator 94.30% Unkown
HY-130504 Propargyl-PEG1-acid ≥97.0% Unkown
HY-N3999 Venuloside A 99.82% Unkown
HY-120139A (R)-KMH-233 Control / Unkown
HY-127042 6,7-Epoxy-latrunculin A Inhibitor / Unkown
HY-129934S Latanoprost ethyl amide-d4 / Unkown
HY-RS07536 LAT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS07537 LAT2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS07538 LATS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS07539 LATS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-147165A VT02956 hydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lat NCBI NCBI:27040
Canis familiaris Lat NCBI NCBI:607947
Macaca fascicularis Lat NCBI NCBI:102143768
Canis lupus familiaris Lat NCBI
Mus musculus Lat NCBI NCBI:16797
Susscrofa domestica Lat NCBI
Leporidae Lat NCBI
Macaca mulatta Lat NCBI NCBI:704656