NUDT22 - nudix hydrolase 22 Gene

Homo sapiens

Gene ID: 84304 | Gene type: protein coding

About NUDT22

This gene has 12 transcripts (splice variants) and 182 orthologues. Ubiquitous expression in duodenum (RPKM 16.3), spleen (RPKM 14.4) and 25 other tissues.

Summary

Enables UDP-sugar diphosphatase activity and metal ion binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NUDT22 Products(4)

mRNA	Protein	Name
NM_001128612.3	NP_001122084.2	uridine diphosphate glucose pyrophosphatase NUDT22 isoform a
NM_001128613.3	NP_001122085.2	uridine diphosphate glucose pyrophosphatase NUDT22 isoform b
NM_001271831.2	NP_001258760.2	uridine diphosphate glucose pyrophosphatase NUDT22 isoform b
NM_032344.4	NP_115720.2	uridine diphosphate glucose pyrophosphatase NUDT22 isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables UDP-sugar diphosphatase activity	IDA IDA: Inferred from direct assay	29413322	GOA
enables metal ion binding	IMP IMP: Inferred from mutant phenotype	29413322	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

uridine diphosphate glucose pyrophosphatase NUDT22

UDPG pyrophosphatase

NUDT22 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	NUDT22	Q9BRQ3	ZNF343	Homo sapiens	Q6P1L6	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF343	Homo sapiens	Q6P1L6	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	TLE5	Homo sapiens	Q08117-2	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	TLE5	Homo sapiens	Q08117-2	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	USP54	Homo sapiens	Q70EL1-9	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	USP54	Homo sapiens	Q70EL1-9	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZNF648	Homo sapiens	Q5T619	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF648	Homo sapiens	Q5T619	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZMYND12	Homo sapiens	Q9H0C1	Validated Y2H	32296183
Intra	NUDT22	Q9BRQ3	ZMYND12	Homo sapiens	Q9H0C1	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZMYND12	Homo sapiens	Q9H0C1	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	LHX3	Homo sapiens	Q9UBR4-2	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	LHX3	Homo sapiens	Q9UBR4-2	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	LHX3	Homo sapiens	Q9UBR4-2	Validated Y2H	32296183
Intra	NUDT22	Q9BRQ3	ZNF19	Homo sapiens	P17023	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZNF19	Homo sapiens	P17023	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	TCF4	Homo sapiens	P15884-3	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	TCF4	Homo sapiens	P15884-3	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	WDR54	Homo sapiens	Q9H977-4	Validated Y2H	32296183
Intra	NUDT22	Q9BRQ3	ZBTB33	Homo sapiens	Q86T24	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZBTB33	Homo sapiens	Q86T24	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF143	Homo sapiens	P52747	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF143	Homo sapiens	P52747	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	SAXO1	Homo sapiens	Q8IYX7	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	SAXO1	Homo sapiens	Q8IYX7	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF655	Homo sapiens	Q8N720	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZNF655	Homo sapiens	Q8N720	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	RUSC1	Homo sapiens	Q9BVN2	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	RUSC1	Homo sapiens	Q9BVN2	Complementation	32296183
Intra	NUDT22	Q9BRQ3	RUSC1	Homo sapiens	Q9BVN2	Validated Y2H	32296183
Intra	NUDT22	Q9BRQ3	RUSC1	Homo sapiens	Q9BVN2	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	TLE5	Homo sapiens	Q08117	Y2H Prey Pooling	25416956
Intra	NUDT22	Q9BRQ3	TLE5	Homo sapiens	Q08117	Y2H Array	25416956
Intra	NUDT22	Q9BRQ3	KLHL26	Homo sapiens	Q53HC5	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	KLHL26	Homo sapiens	Q53HC5	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	DNAL4	Homo sapiens	O96015	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	DNAL4	Homo sapiens	O96015	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF581	Homo sapiens	Q9P0T4	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	32296183
Intra	NUDT22	Q9BRQ3	ZNF398	Homo sapiens	Q8TD17	Y2H Array	32296183
Intra	NUDT22	Q9BRQ3	ZNF398	Homo sapiens	Q8TD17	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ARID5A	Homo sapiens	Q03989	Y2H Prey Pooling	32296183
Intra	NUDT22	Q9BRQ3	ARID5A	Homo sapiens	Q03989	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09670	NUDT22 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	NUDT22	VGNC	VGNC:75475
Canis familiaris	NUDT22	VGNC	VGNC:51884
Bos taurus	NUDT22	VGNC	VGNC:32337
Felis catus	NUDT22	VGNC	VGNC:81967
Rattus norvegicus	NUDT22	RGD	RGD:735224
Mus musculus	NUDT22	MGD	MGI:1915573

Name
Email *

	Sorry, but the email address you supplied was invalid.