PHYKPL - 5-phosphohydroxy-L-lysine phospho-lyase Gene

Homo sapiens (human)

Also known as PHLU; AGXT2L2

Gene ID: 85007 | Gene type: protein coding

About PHYKPL

Summary

This is a nuclear gene encoding a mitochondrial Enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

PHYKPL Products(1)

mRNA	Protein	Name
XR_008487187.1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	21044950	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

5-phosphohydroxy-L-lysine phospho-lyase

5-phosphonooxy-L-lysine phospho-lyase

alanine--glyoxylate aminotransferase 2-like 2

PHYKPL Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PHYKPL	Q8IUZ5	VAC14	Homo sapiens	Q08AM6	Y2H Array	25416956
Intra	PHYKPL	Q8IUZ5	VAC14	Homo sapiens	Q08AM6	Y2H Array	29892012
Intra	PHYKPL	Q8IUZ5	LNX2	Homo sapiens	Q8N448	Y2H Array	29892012
Intra	PHYKPL	Q8IUZ5	LNX2	Homo sapiens	Q8N448	Y2H Array	31515488
Intra	PHYKPL	Q8IUZ5	USO1	Homo sapiens	O60763	Validated Y2H	25416956
Intra	PHYKPL	Q8IUZ5	USO1	Homo sapiens	O60763	Y2H Array	25416956
Intra	PHYKPL	Q8IUZ5	PHYKPL	Homo sapiens	Q8IUZ5	Y2H Pooling	16189514
Intra	PHYKPL	Q8IUZ5	PHYKPL	Homo sapiens	Q8IUZ5	Y2H Array	31515488
Intra	PHYKPL	Q8IUZ5	PHYKPL	Homo sapiens	Q8IUZ5	Y2H Prey Pooling	32296183
Intra	PHYKPL	Q8IUZ5	PHYKPL	Homo sapiens	Q8IUZ5	Validated Y2H	32296183
Intra	PHYKPL	Q8IUZ5	PHYKPL	Homo sapiens	Q8IUZ5	Y2H Array	25416956
Intra	PHYKPL	Q8IUZ5	POT1	Homo sapiens	Q9NUX5	Pull Down	21044950
Intra	PHYKPL	Q8IUZ5	PHYKPL	Homo sapiens	Q8IUZ5	Y2H Array	32296183
Intra	PHYKPL	Q8IUZ5	GIT1	Homo sapiens	Q9Y2X7	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Name
Email *

	Sorry, but the email address you supplied was invalid.