CEP95 - centrosomal protein 95 Gene

Homo sapiens

Also known as CCDC45

Gene ID: 90799 | Gene type: protein coding

About CEP95

This gene has 18 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in testis (RPKM 9.3), bone marrow (RPKM 8.3) and 25 other tissues.

Summary

Located in centrosome and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]

CEP95 Products(2)

mRNA	Protein	Name
NM_001316990.2	NP_001303919.1	centrosomal protein of 95 kDa isoform 2
NM_138363.3	NP_612372.1	centrosomal protein of 95 kDa isoform 1

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	15231747	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in centrosome	IDA IDA: Inferred from direct assay	21399614	GOA
located in spindle pole	IDA IDA: Inferred from direct assay	21399614	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

centrosomal protein of 95 kDa

centrosomal protein 95kDa

CEP95 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CEP95	Q96GE4	FAM9B	Homo sapiens	Q8IZU0	Y2H Array	31515488
Intra	CEP95	Q96GE4	FAM9B	Homo sapiens	Q8IZU0	Y2H Prey Pooling	25416956
Intra	CEP95	Q96GE4	FAM9B	Homo sapiens	Q8IZU0	Validated Y2H	25416956
Intra	CEP95	Q96GE4	HOOK2	Homo sapiens	Q96ED9-2	Y2H Array	32296183
Intra	CEP95	Q96GE4	HOOK2	Homo sapiens	Q96ED9-2	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
Intra	CEP95	Q96GE4	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
Intra	CEP95	Q96GE4	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	31515488
Intra	CEP95	Q96GE4	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	CEP95	Q96GE4	TP53BP2	Homo sapiens	Q05BL1	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	TP53BP2	Homo sapiens	Q05BL1	Y2H Array	32296183
Intra	CEP95	Q96GE4	CCDC125	Homo sapiens	Q86Z20	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	CCDC125	Homo sapiens	Q86Z20	Y2H Array	32296183
Intra	CEP95	Q96GE4	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
Intra	CEP95	Q96GE4	MCC	Homo sapiens	P23508	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	MCC	Homo sapiens	P23508	Y2H Array	32296183
Intra	CEP95	Q96GE4	CARD10	Homo sapiens	Q9BWT7	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	CARD10	Homo sapiens	Q9BWT7	Validated Y2H	32296183
Intra	CEP95	Q96GE4	CARD10	Homo sapiens	Q9BWT7	Y2H Array	32296183
Intra	CEP95	Q96GE4	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	CEP95	Q96GE4	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	CEP95	Q96GE4	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	HMG20A	Homo sapiens	Q9NP66	Y2H Prey Pooling	32296183
Intra	CEP95	Q96GE4	HMG20A	Homo sapiens	Q9NP66	Validated Y2H	32296183
Intra	CEP95	Q96GE4	HMG20A	Homo sapiens	Q9NP66	Y2H Array	32296183
Intra	CEP95	Q96GE4	MTUS2	Homo sapiens	Q5JR59	Y2H Prey Pooling	25416956
Intra	CEP95	Q96GE4	MTUS2	Homo sapiens	Q5JR59	Validated Y2H	25416956
Intra	CEP95	Q96GE4	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	CEP95	Q96GE4	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	CEP95	Q96GE4	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02529	CEP95 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CEP95	MGD	MGI:2443502
Rattus norvegicus	CEP95	RGD	RGD:1309655
Bos taurus	CEP95	VGNC	VGNC:27219
Canis familiaris	CEP95	VGNC	VGNC:39143
Macaca mulatta	CEP95	VGNC	VGNC:71095
Felis catus	CEP95	VGNC	VGNC:60789

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