2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR Calcium Channel GABA Receptor
  4. GeX-2

GeX-2 is a truncated analogue of αO-conotoxin. GeX-2 activates GABAB receptor. GeX-2 inhibits α9α10 nAChR and CaV2.2 channels. GeX-2 alleviates pain in the rat model of chronic constriction injury.

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GeX-2 Chemical Structure

GeX-2 Chemical Structure

CAS No. : 2900996-95-2

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GeX-2 Related Antibodies

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Description

GeX-2 is a truncated analogue of αO-conotoxin. GeX-2 activates GABAB receptor. GeX-2 inhibits α9α10 nAChR and CaV2.2 channels. GeX-2 alleviates pain in the rat model of chronic constriction injury[1].

Molecular Weight

2441.72

Formula

C103H169N43O27
CAS No.
Sequence

GRYRSPYDRRRRYRRITD-NH2
Sequence Shortening

Gly-Arg-Tyr-Arg-Ser-Pro-Tyr-Asp-Arg-Arg-Arg-Arg-Tyr-Arg-Arg-Ile-Thr-Asp-NH2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GeX-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GeX-22900996-95-2GeX2GeX 2nAChRCalcium ChannelGABA ReceptorNicotinic acetylcholine receptorsCa2+ channelsCa channelsGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorαO-conotoxinpainratInhibitorinhibitorinhibit

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