2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. GNX-865

GNX-865 is a mitochondrial permeability transition pore (mPTP) inhibitor that protects against ischemia-reperfusion injury in vivo.

For research use only. We do not sell to patients.

GNX-865 Chemical Structure

GNX-865 Chemical Structure

CAS No. : 1223568-82-8

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Based on 1 publication(s) in Google Scholar

GNX-865 Related Antibodies

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Description

GNX-865 is a mitochondrial permeability transition pore (mPTP) inhibitor that protects against ischemia-reperfusion injury in vivo[1].

Molecular Weight

303.74

Formula

C16H14ClNO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(/C=C/C1=CC=C(C(O)=C1)OC)NC2=CC=CC(Cl)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (16.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2923 mL 16.4614 mL 32.9229 mL
5 mM 0.6585 mL 3.2923 mL 6.5846 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2923 mL 16.4614 mL 32.9229 mL 82.3072 mL
5 mM 0.6585 mL 3.2923 mL 6.5846 mL 16.4614 mL
10 mM 0.3292 mL 1.6461 mL 3.2923 mL 8.2307 mL
15 mM 0.2195 mL 1.0974 mL 2.1949 mL 5.4871 mL
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GNX-865 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GNX-8651223568-82-8GNX865GNX 865Mitochondrial MetabolismmPTP Inhibitorischemia-reperfusion injuryInhibitorinhibitorinhibit

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HY-119909
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