2. Metabolic Enzyme/Protease
  3. Lactate Dehydrogenase
  4. Isomalt

Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes.

For research use only. We do not sell to patients.

Isomalt Chemical Structure

Isomalt Chemical Structure

CAS No. : 64519-82-0

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Isomalt:

Isomalt Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].

In Vivo

The chronic toxicity of orally administered isomalt as a part of diet has been studied in animals and it was found to be a safe substance. It did not affect the mortality rate of the animals, and there was no evidence of carcinogenicity, or adverse effects on fertility, reproductive performance or development[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

688.62

Formula

C24H48O22
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@@H](O1)[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO.O[C@H]([C@@H](CO[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)O)[C@H](O)[C@@H](CO)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (363.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4522 mL 7.2609 mL 14.5218 mL
5 mM 0.2904 mL 1.4522 mL 2.9044 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (145.22 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation

Purity: ≥98.0%

Data Sheet (280 KB) SDS (393 KB)

COA (261 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4522 mL 7.2609 mL 14.5218 mL 36.3045 mL
5 mM 0.2904 mL 1.4522 mL 2.9044 mL 7.2609 mL
10 mM 0.1452 mL 0.7261 mL 1.4522 mL 3.6304 mL
15 mM 0.0968 mL 0.4841 mL 0.9681 mL 2.4203 mL
20 mM 0.0726 mL 0.3630 mL 0.7261 mL 1.8152 mL
25 mM 0.0581 mL 0.2904 mL 0.5809 mL 1.4522 mL
30 mM 0.0484 mL 0.2420 mL 0.4841 mL 1.2101 mL
40 mM 0.0363 mL 0.1815 mL 0.3630 mL 0.9076 mL
50 mM 0.0290 mL 0.1452 mL 0.2904 mL 0.7261 mL
60 mM 0.0242 mL 0.1210 mL 0.2420 mL 0.6051 mL
80 mM 0.0182 mL 0.0908 mL 0.1815 mL 0.4538 mL
100 mM 0.0145 mL 0.0726 mL 0.1452 mL 0.3630 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Isomalt Related Classifications

Keywords:

Isomalt64519-82-0PalatinitolLactate DehydrogenaseLDHstabilizingexcipientsfreeze-driedsweeteningagentfoodindustryoralInhibitorinhibitorinhibit

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