1. Membrane Transporter/Ion Channel
  2. Monocarboxylate Transporter
  3. Lactate transportor 1

Lactate transportor 1 (compound 1) is an active lactate transporter in living cells. Lactate transportor 1 displays the cytotoxic effect, with IC50 values of 3.36, 3.27,5.58 and 7.66 μM in Hela, CAL27, MCF7 and MCF10A, respectively. Lactate transportor 1 has an additive effect with Cisplatin (HY-17394) observed in HeLa cells.

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Lactate transportor 1 Chemical Structure

Lactate transportor 1 Chemical Structure

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Description

Lactate transportor 1 (compound 1) is an active lactate transporter in living cells. Lactate transportor 1 displays the cytotoxic effect, with IC50 values of 3.36, 3.27,5.58 and 7.66 μM in Hela, CAL27, MCF7 and MCF10A, respectively. Lactate transportor 1 has an additive effect with Cisplatin (HY-17394) observed in HeLa cells[1].

IC50 & Target

3.36, 3.27,5.58 and 7.66 μM(Hela, CAL27, MCF7 and MCF10A)[1]

Molecular Weight

494.07

Formula

C28H36ClN5O

SMILES

CC(C)(C)C1=CC=C(N2N=NC(C3=CC(OC)=C(/C=[NH+]/C4(C[C@@H](C5)C6)C[C@H]5C[C@H]6C4)N3)=C2)C=C1.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lactate transportor 1
Cat. No.:
HY-155382
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