LDL-IN-2

Cat. No.: HY-120651 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

LDL-IN-2 (compound 3) is an antioxidant against copper mediated low-density lipoproteins (LDL) oxidation.

For research use only. We do not sell to patients.

LDL-IN-2 Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Description

LDL-IN-2 (compound 3) is an antioxidant against copper mediated low-density lipoproteins (LDL) oxidation^[1].

Molecular Weight

265.26

Formula

C₁₃H₁₅NO₅

CAS No.

778624-05-8

Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](C(OC)=O)NC(/C=C/C1=CC=C(O)C(O)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 30 mg/mL (113.10 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7699 mL	18.8494 mL	37.6989 mL
5 mM	0.7540 mL	3.7699 mL	7.5398 mL
10 mM	0.3770 mL	1.8849 mL	3.7699 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Sangku Lee, et al. Synthesis of cinnamic acid derivatives and their inhibitory effects on LDL-oxidation, acyl CoA:cholesterol acyltransferase-1 and -2 activity, and decrease of HDL-particle size. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4677-81. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7699 mL	18.8494 mL	37.6989 mL	94.2472 mL
	5 mM	0.7540 mL	3.7699 mL	7.5398 mL	18.8494 mL
	10 mM	0.3770 mL	1.8849 mL	3.7699 mL	9.4247 mL
	15 mM	0.2513 mL	1.2566 mL	2.5133 mL	6.2831 mL
	20 mM	0.1885 mL	0.9425 mL	1.8849 mL	4.7124 mL
	25 mM	0.1508 mL	0.7540 mL	1.5080 mL	3.7699 mL
	30 mM	0.1257 mL	0.6283 mL	1.2566 mL	3.1416 mL
	40 mM	0.0942 mL	0.4712 mL	0.9425 mL	2.3562 mL
	50 mM	0.0754 mL	0.3770 mL	0.7540 mL	1.8849 mL
	60 mM	0.0628 mL	0.3142 mL	0.6283 mL	1.5708 mL
	80 mM	0.0471 mL	0.2356 mL	0.4712 mL	1.1781 mL
	100 mM	0.0377 mL	0.1885 mL	0.3770 mL	0.9425 mL

LDL-IN-2 Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDL-IN-2778624-05-8LDLRLow-density lipoprotein receptorcopperACAT-1LDL-oxidationInhibitorinhibitorinhibit

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LDL-IN-2

LDL-IN-2 Related Antibodies

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