MO-I-500

Cat. No.: HY-117426 Purity: 99.10%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

MO-I-500 is a pharmacological of FTO inhibitor with an IC₅₀ of 8.7 μM for the inhibition of purified FTO demethylase catalyzing demethylation of an artificial small methylated substrate. MO-I-500 can be used for the research of rare panresistant triple-negative inflammatory breast cancer.

For research use only. We do not sell to patients.

MO-I-500 Chemical Structure

CAS No. : 1585219-04-0

Size	Price	Stock
10 mg	USD 564	Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

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Purity & Documentation
References
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Description

Molecular Weight

317.75

Formula

C₁₂H₁₂ClNO₅S

CAS No.

1585219-04-0

Appearance

Solid

Color

White to off-white

SMILES

CCS(=O)(NC1=C(C(O)=C(O1)C2=CC=C(C=C2)Cl)O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 31.8 mg/mL (100.08 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1471 mL	15.7356 mL	31.4713 mL
5 mM	0.6294 mL	3.1471 mL	6.2943 mL
10 mM	0.3147 mL	1.5736 mL	3.1471 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.10%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (250 KB) Elemental Analysis Report (108 KB)

Handling Instructions (2659 KB)

References

[1]. Balraj Singh et al. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One. 2016 Jul 8;11(7):e0159072. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1471 mL	15.7356 mL	31.4713 mL	78.6782 mL
	5 mM	0.6294 mL	3.1471 mL	6.2943 mL	15.7356 mL
	10 mM	0.3147 mL	1.5736 mL	3.1471 mL	7.8678 mL
	15 mM	0.2098 mL	1.0490 mL	2.0981 mL	5.2452 mL
	20 mM	0.1574 mL	0.7868 mL	1.5736 mL	3.9339 mL
	25 mM	0.1259 mL	0.6294 mL	1.2589 mL	3.1471 mL
	30 mM	0.1049 mL	0.5245 mL	1.0490 mL	2.6226 mL
	40 mM	0.0787 mL	0.3934 mL	0.7868 mL	1.9670 mL
	50 mM	0.0629 mL	0.3147 mL	0.6294 mL	1.5736 mL
	60 mM	0.0525 mL	0.2623 mL	0.5245 mL	1.3113 mL
	80 mM	0.0393 mL	0.1967 mL	0.3934 mL	0.9835 mL
	100 mM	0.0315 mL	0.1574 mL	0.3147 mL	0.7868 mL

MO-I-500 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MO-I-5001585219-04-0OthersFTOFTO demethylasetriple-negative inflammatory breast cancerInhibitorinhibitorinhibit

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