MPO (Synonyms: 5-(4-Methoxyphenyl)oxazole)

Cat. No.: HY-114521: FAQs
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MPO (5-(4'-Methoxyphenyl)-oxazole) is a Caenorhabditis elegans hatch and growth inhibitor that isolated from fungal culture broth.

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MPO Chemical Structure

CAS No. : 1011-51-4

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Biological Activity
Purity & Documentation
References
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Description

MPO (5-(4'-Methoxyphenyl)-oxazole) is a Caenorhabditis elegans hatch and growth inhibitor that isolated from fungal culture broth^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BT-549	GI₅₀	> 100 μM Compound: 20	Cytotoxicity against human BT549 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method Cytotoxicity against human BT549 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method	[PMID: 29053266]
HCC1937	GI₅₀	> 100 μM Compound: 20	Cytotoxicity against human HCC1937 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method Cytotoxicity against human HCC1937 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method	[PMID: 29053266]
HCC70	GI₅₀	> 100 μM Compound: 20	Cytotoxicity against human HCC70 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method Cytotoxicity against human HCC70 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method	[PMID: 29053266]
HeLa	EC₅₀	30 μM Compound: 1, MPO	Cytotoxic activity against human HeLa cells after 48 hrs by WST8 assay Cytotoxic activity against human HeLa cells after 48 hrs by WST8 assay	[PMID: 25488842]
HL-60	EC₅₀	> 100 μM Compound: 1, MPO	Cytotoxic activity against human HL60 cells after 48 hrs by WST8 assay Cytotoxic activity against human HL60 cells after 48 hrs by WST8 assay	[PMID: 25488842]
MDA-MB-231	GI₅₀	> 100 μM Compound: 20	Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method	[PMID: 29053266]
MDA-MB-453	GI₅₀	> 100 μM Compound: 20	Cytotoxicity against human MDA-MB-453 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method Cytotoxicity against human MDA-MB-453 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method	[PMID: 29053266]

Molecular Weight

175.18

Formula

C₁₀H₉NO₂

CAS No.

1011-51-4

SMILES

COC1=CC=C(C=C1)C2=CN=CO2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yamamuro D, et al. Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives. Bioorg Med Chem Lett. 2015 Jan 15;25(2):313-6. [Content Brief]

MPO Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MPO1011-51-45-(4-Methoxyphenyl)oxazoleParasite5-(4'-Methoxyphenyl)-oxazoleCaenorhabditis elegansHatch inhibition.Inhibitorinhibitorinhibit

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