OVA-E1 peptide TFA

Cat. No.: HY-P2319A Purity: 98.03%: Data Sheet
SDS

COA
Handling Instructions Technical Support

OVA-E1 peptide TFA, is an antagonist variant of SIINFEKL [OVA (257-264). OVA-E1 peptide, activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

OVA-E1 peptide TFA Chemical Structure

CAS No. : 1262750-80-0

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of OVA-E1 peptide TFA:

OVA-E1 peptide Get quote

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•Related Screening Libraries:

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

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JNK1 JNK2 JNK3 JNK

Biological Activity
Purity & Documentation
References
Customer Review

Description

OVA-E1 peptide TFA, is an antagonist variant of SIINFEKL [OVA (257-264). OVA-E1 peptide, activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes^[1].

Molecular Weight

1119.19

Formula

C₄₉H₇₇F₃N₁₀O₁₆

CAS No.

1262750-80-0

Appearance

Solid

Color

White to off-white

Sequence

Glu-Ile-Ile-Asn-Phe-Glu-Lys-Leu

Sequence Shortening

EIINFEKL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Stored under nitrogen, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Purity & Documentation

Purity: 98.03%

Select Batch:

Data Sheet (257 KB) SDS (252 KB)

COA (249 KB) RP-HPLC (256 KB) MS (187 KB) Elemental Analysis Report (108 KB)

Handling Instructions (2659 KB)

References

[1]. Leandro J Carreño, et al. The Half-Life of the T-cell receptor/peptide-major Histocompatibility Complex Interaction Can Modulate T-cell Activation in Response to Bacterial Challenge. Immunology. 2007 Jun;121(2):227-37. [Content Brief]