2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Prazobind

Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50=1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes.

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Prazobind Chemical Structure

Prazobind Chemical Structure

CAS No. : 107021-36-3

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Based on 1 publication(s) in Google Scholar

Prazobind Related Antibodies

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α adrenergic receptor β adrenergic receptor

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Description

Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC50=1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes[1][2].

Molecular Weight

421.49

Formula

C23H27N5O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=NC(N(CC2)CCN2C(C3=CC4CCC3C=C4)=O)=NC(C=C5OC)=C1C=C5OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 0.1 mg/mL (0.24 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation

Purity: 96.20%

SDS (251 KB)

COA (249 KB)

Handling Instructions (2659 KB)
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Prazobind Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prazobind107021-36-3SZL 49SZL49SZL-49Adrenergic ReceptorBeta Receptoralpha 1-adrenoceptoralpha 1Aalpha 1BInhibitorinhibitorinhibit

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