2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. Prednisone acetate-d3

Prednisone acetate-d3  (Synonyms: Prednisone 21-acetate-d3)

Cat. No.: HY-B1832S Purity: 96.47%
COA Handling Instructions

Molarity Calculator

Prednisone acetate-d3 is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].

For research use only. We do not sell to patients.

Prednisone acetate-d<sub>3</sub> Chemical Structure

Prednisone acetate-d3 Chemical Structure

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1 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Prednisone acetate-d3:

Prednisone acetate-d3 Related Antibodies

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Description

Prednisone acetate-d3 is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Prednisone acetate-d3 Related Antibodies
Molecular Weight

403.48

Formula

C23H25D3O6
Unlabeled CAS

125-10-0
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]1(C2)[C@](C(COC(C([2H])([2H])[2H])=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (61.96 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4784 mL 12.3922 mL 24.7844 mL
5 mM 0.4957 mL 2.4784 mL 4.9569 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 96.47%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4784 mL 12.3922 mL 24.7844 mL 61.9609 mL
5 mM 0.4957 mL 2.4784 mL 4.9569 mL 12.3922 mL
10 mM 0.2478 mL 1.2392 mL 2.4784 mL 6.1961 mL
15 mM 0.1652 mL 0.8261 mL 1.6523 mL 4.1307 mL
20 mM 0.1239 mL 0.6196 mL 1.2392 mL 3.0980 mL
25 mM 0.0991 mL 0.4957 mL 0.9914 mL 2.4784 mL
30 mM 0.0826 mL 0.4131 mL 0.8261 mL 2.0654 mL
40 mM 0.0620 mL 0.3098 mL 0.6196 mL 1.5490 mL
50 mM 0.0496 mL 0.2478 mL 0.4957 mL 1.2392 mL
60 mM 0.0413 mL 0.2065 mL 0.4131 mL 1.0327 mL
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Prednisone acetate-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prednisone acetate-d3Prednisone 21-acetate-d3Glucocorticoid ReceptorInhibitorinhibitorinhibit

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