(R)-(-)-2-Butanol

Name: (R)-(-)-2-Butanol
Brand: MedChemExpress
SKU: HY-W087952
Rating: 4.5 (1 reviews)

Cat. No.: HY-W087952 Purity: 99.71%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(R)-(-)-2-Butanol is released by the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling.

For research use only. We do not sell to patients.

(R)-(-)-2-Butanol Chemical Structure

CAS No. : 14898-79-4

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 33	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 33	In-stock	Estimated Time of Arrival: December 31
Liquid
1 g	USD 30	In-stock	Estimated Time of Arrival: December 31
5 g	USD 60	In-stock	Estimated Time of Arrival: December 31
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50 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Description

(R)-(-)-2-Butanol is released by the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling^[1]^[2].

Molecular Weight

74.12

Formula

C₄H₁₀O

CAS No.

14898-79-4

Appearance

Liquid (Density: 0.807 g/cm³)

Color

Colorless to light yellow

SMILES

C[C@@H](O)CC

Structure Classification

Others

Initial Source

Microorganisms

endophytic bacterium ETR-B22

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (1349.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	13.4916 mL	67.4582 mL	134.9164 mL
5 mM	2.6983 mL	13.4916 mL	26.9833 mL
10 mM	1.3492 mL	6.7458 mL	13.4916 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (33.73 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (33.73 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (33.73 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.71%

Select Batch:

Data Sheet (272 KB) SDS (605 KB)

COA (248 KB) HNMR (116 KB) GC (204 KB)

Handling Instructions (2659 KB)

References

[1]. N Fujiwara-Tsujii, et al. Age-dependent changes in the ratio of (R)- and (S)-2-butanol released by virgin females of Dasylepida ishigakiensis (Coleoptera: Scarabaeidae). Bull Entomol Res. 2012 Dec;102(6):730-6. [Content Brief]

[2]. Aram Hong, et al. Induced Circular Dichroism of Jet-Cooled Phenol Complexes with ( R)-(-)-2-Butanol. J Phys Chem A. 2019 Oct 17;123(41):8913-8920. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	13.4916 mL	67.4582 mL	134.9163 mL	337.2909 mL
	5 mM	2.6983 mL	13.4916 mL	26.9833 mL	67.4582 mL
	10 mM	1.3492 mL	6.7458 mL	13.4916 mL	33.7291 mL
	15 mM	0.8994 mL	4.4972 mL	8.9944 mL	22.4861 mL
	20 mM	0.6746 mL	3.3729 mL	6.7458 mL	16.8645 mL
	25 mM	0.5397 mL	2.6983 mL	5.3967 mL	13.4916 mL
	30 mM	0.4497 mL	2.2486 mL	4.4972 mL	11.2430 mL
	40 mM	0.3373 mL	1.6865 mL	3.3729 mL	8.4323 mL
	50 mM	0.2698 mL	1.3492 mL	2.6983 mL	6.7458 mL
	60 mM	0.2249 mL	1.1243 mL	2.2486 mL	5.6215 mL
	80 mM	0.1686 mL	0.8432 mL	1.6865 mL	4.2161 mL
	100 mM	0.1349 mL	0.6746 mL	1.3492 mL	3.3729 mL

(R)-(-)-2-Butanol Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-(-)-2-Butanol14898-79-4OthersInhibitorinhibitorinhibit

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(R)-(-)-2-Butanol

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(R)-(-)-2-Butanol Related Antibodies

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Complete Stock Solution Preparation Table

(R)-(-)-2-Butanol Related Classifications

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