ADAM8 Protein, Human (HEK293, His)

ADAM8 protein is suggested to be involved in leukocyte extravasation, indicating its potential role in facilitating the migration of white blood cells from blood vessels into surrounding tissues. This implies ADAM8's contribution to immune responses by regulating leukocyte movement across the endothelial barrier, a crucial step in inflammatory and immune surveillance processes. ADAM8 Protein, Human (HEK293, His) is the recombinant human-derived ADAM8 protein, expressed by HEK293 , with C-His labeled tag. The total length of ADAM8 Protein, Human (HEK293, His) is 639 a.a., with molecular weight of ~71 kDa.

ADAM8 protein is speculated to participate in the process of leukocyte extravasation, implying its potential role in facilitating the migration of white blood cells from blood vessels into surrounding tissues. This suggests that ADAM8 may contribute to immune responses by regulating the movement of leukocytes across the endothelial barrier, an essential step in the inflammatory and immune surveillance processes.

Immobilized Human ADAM8, His Tag at 0.5 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC₅₀ of ≤8.1 ng/mL determined by ELISA.

Human

HEK293

C-His

AAI15405.1 (I17-P655)

101  [NCBI]

Approximately 71 kDa

Greater than 95% as determined by reducing SDS-PAGE or Tris-Bis PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.