Resveratroloside (Synonyms: Resveratrol glycoside; trans-Resveratrol 4'-O-β-D-glucopyranoside)

Name: Resveratroloside
Brand: MedChemExpress
SKU: HY-N4195
Rating: 5.0 (2 reviews)

Cat. No.: HY-N4195 Purity: 99.88%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Resveratroloside (Resveratrol glycoside) is a competitive inhibitior of α-glucosidase with an IC₅₀ of 22.9 μM. Resveratroloside has the ability to regulate PBG (postprandial blood glucose) levels. Resveratroloside exhibits cardioprotective effect.

For research use only. We do not sell to patients.

Resveratroloside Chemical Structure

CAS No. : 38963-95-0

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote
50 mg	Get quote

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Customer Review

Based on 2 publication(s) in Google Scholar

1 Publications Citing Use of MCE Resveratroloside

•Behav Brain Res. 2023 Feb 20;443:114326. [Abstract]

: Resveratroloside purchased from MedChemExpress. Usage Cited in: Behav Brain Res. 2023 Feb 20;443:114326. [Abstract]; Resveratroloside (resveratrol glycoside; RG; 250 mg/kg; i.p.; single daily for 7 days) alleviates the abnormal high expression of ERS-related protein PERK/CHOP in the whole brain induced by LPS in mice.

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References
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Description

Molecular Weight

390.38

Formula

C₂₀H₂₂O₈

CAS No.

38963-95-0

Appearance

Solid

Color

White to off-white

SMILES

OC1=CC(O)=CC(/C=C/C(C=C2)=CC=C2O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)=C1

Structure Classification

Stilbenes

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (640.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5616 mL	12.8080 mL	25.6161 mL
5 mM	0.5123 mL	2.5616 mL	5.1232 mL
10 mM	0.2562 mL	1.2808 mL	2.5616 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (6.40 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (6.40 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (6.40 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (248 KB) HNMR (88 KB) RP-HPLC (252 KB)

Handling Instructions (2659 KB)

References

[1]. Zhao X, et al. Resveratroloside Alleviates Postprandial Hyperglycemia in Diabetic Mice by Competitively Inhibiting α-Glucosidase. J Agric Food Chem. 2019 Mar 13;67(10):2886-2893. [Content Brief]

[2]. Naumenko SE, et al. Cardioprotective effect of resveratrol and resveratroloside. Cardiovasc Hematol Agents Med Chem. 2013 Sep;11(3):207-10. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5616 mL	12.8080 mL	25.6161 mL	64.0402 mL
	5 mM	0.5123 mL	2.5616 mL	5.1232 mL	12.8080 mL
	10 mM	0.2562 mL	1.2808 mL	2.5616 mL	6.4040 mL
	15 mM	0.1708 mL	0.8539 mL	1.7077 mL	4.2693 mL
	20 mM	0.1281 mL	0.6404 mL	1.2808 mL	3.2020 mL
	25 mM	0.1025 mL	0.5123 mL	1.0246 mL	2.5616 mL
	30 mM	0.0854 mL	0.4269 mL	0.8539 mL	2.1347 mL
	40 mM	0.0640 mL	0.3202 mL	0.6404 mL	1.6010 mL
	50 mM	0.0512 mL	0.2562 mL	0.5123 mL	1.2808 mL
	60 mM	0.0427 mL	0.2135 mL	0.4269 mL	1.0673 mL
	80 mM	0.0320 mL	0.1601 mL	0.3202 mL	0.8005 mL
	100 mM	0.0256 mL	0.1281 mL	0.2562 mL	0.6404 mL

Resveratroloside Related Classifications

Metabolic Disease Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Resveratroloside38963-95-0Resveratrol glycoside trans-Resveratrol 4'-O-β-D-glucopyranosideGlycosidaseα-glucosidasediabetescardioprotectiveInhibitorinhibitorinhibit

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Resveratroloside (Synonyms: Resveratrol glycoside; trans-Resveratrol 4'-O-β-D-glucopyranoside)

Customer Review

Resveratroloside Related Antibodies

1 Publications Citing Use of MCE Resveratroloside

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Resveratroloside Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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SAFETY DATA SHEET (SDS)

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