2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. Rhapontigenin 3'-O-glucoside

Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent.

For research use only. We do not sell to patients.

Rhapontigenin 3'-O-glucoside Chemical Structure

Rhapontigenin 3'-O-glucoside Chemical Structure

CAS No. : 94356-22-6

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1 mg USD 95 In-stock
5 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

Rhapontigenin 3'-O-glucoside Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Rhapontigenin 3'-O-glucoside

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent[1].

In Vitro

Rhapontigenin exhibits a potent and selective inhibition of human P450 1A1 with an IC50 of 0.4 μM. Rhapontigenin shows 400-fold selectivity for P450 1A1 over P450 1A2 and 23-fold selectivity for P450 1A1 over P450 1B1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Rhapontigenin 3'-O-glucoside Related Antibodies
Molecular Weight

420.41

Formula

C21H24O9
CAS No.
Appearance

Solid

Color

Off-white to gray

SMILES

O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC(/C=C/C3=CC(O)=CC(O)=C3)=CC=C2OC
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (237.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3786 mL 11.8932 mL 23.7863 mL
5 mM 0.4757 mL 2.3786 mL 4.7573 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3786 mL 11.8932 mL 23.7863 mL 59.4658 mL
5 mM 0.4757 mL 2.3786 mL 4.7573 mL 11.8932 mL
10 mM 0.2379 mL 1.1893 mL 2.3786 mL 5.9466 mL
15 mM 0.1586 mL 0.7929 mL 1.5858 mL 3.9644 mL
20 mM 0.1189 mL 0.5947 mL 1.1893 mL 2.9733 mL
25 mM 0.0951 mL 0.4757 mL 0.9515 mL 2.3786 mL
30 mM 0.0793 mL 0.3964 mL 0.7929 mL 1.9822 mL
40 mM 0.0595 mL 0.2973 mL 0.5947 mL 1.4866 mL
50 mM 0.0476 mL 0.2379 mL 0.4757 mL 1.1893 mL
60 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.9911 mL
80 mM 0.0297 mL 0.1487 mL 0.2973 mL 0.7433 mL
100 mM 0.0238 mL 0.1189 mL 0.2379 mL 0.5947 mL
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Rhapontigenin 3'-O-glucoside Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rhapontigenin 3'-O-glucoside94356-22-6Cytochrome P450CYPsInhibitorinhibitorinhibit

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