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CEL

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Compare Product Name Species Source
  • HY-P74569
    SDF-1 Protein, Canine

    Stromal CELl-Derived Factor 1; SDF-1; IRH; hIRH; PBSF; CXCL12; SDF1

    		 Canine E. coli
    SDF-1 (stromal cell-derived factor-1) is a homeostatic chemokine that binds CXCR4 and CXCR7 receptors and physiologically functions in hematopoiesis, leucocyte trafficking, cardiogenesis, and neurogenesis. SDF-1 is constitutively expressed in several organs including lung, liver, skeletal muscle, brain, kidney, heart, skin, and bone marrow. SDF-1 has an essential role in neural and vascular development, hematopoiesis, cancer and in immunity. SDF-1 Protein, Canine is produced in E. coli, and consists of 72 amino acids (K22-M93).
  • HY-P79111
    SCF Protein, Canine

    Kit ligand; Mast CELl growth factor; MGF; Stem CELl Factor; SCF; c-Kit ligand; KITLG

    		Canine E. coli
    SCF protein critically promotes mast cell proliferation, enhancing both myeloid and lymphoid hematopoietic progenitor proliferation in bone marrow. Additionally, SCF facilitates cell-cell adhesion and synergizes with other cytokines, potentially interleukins. As a homodimer, SCF is connected non-covalently, contributing to hematopoietic processes and immune responses. SCF Protein, Canine is the recombinant canine-derived SCF protein, expressed by E. coli , with tag free. The total length of SCF Protein, Canine is 165 a.a., with molecular weight of ~19 kDa.
  • HY-P76803
    CD3D Protein, Canine (HEK293, Fc)

    T-CELl Surface Glycoprotein CD3 Delta Chain; T-CELl Receptor T3 Delta Chain; CD3d; CD3D; T3D

    		 Canine HEK293
    CD3D protein is a component of the TCR-CD3 complex on T lymphocytes and plays a key role in adaptive immunity. It transmits signals through the CD3D, CD3E, CD3G, and CD3Z chains upon TCR engagement. CD3D Protein, Canine (HEK293, Fc) is the recombinant canine-derived CD3D protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P77320
    CD3 epsilon Protein, Canine (HEK293, Fc)

    T-CELl Surface Glycoprotein CD3 Epsilon Chain; T-CELl Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E

    		 Canine HEK293
    The CD3 ε protein on lymphocytes is a component of the TCR-CD3 complex and is critical for adaptive immune responses. When APC is activated, TCR signals transmitted by CD3D, CD3E, CD3G, and CD3Z initiate pathways through ITAM. CD3 epsilon Protein, Canine (HEK293, Fc) is the recombinant canine-derived CD3 epsilon protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P73214
    IL-4 Protein, Canine
    1 Publications Verification

    Interleukin-4; IL-4; B-CELl stimulatory factor 1; BSF-1

    		 Canine E. coli
    The IL-4 protein actively participates in the B cell activation process, acting as a costimulator for DNA synthesis. It induces the expression of class II MHC molecules on resting B cells, enhances IgE and IgG1 secretion and cell surface expression, and modulates CD23 expression on lymphocytes and monocytes. IL-4 Protein, Canine is the recombinant canine-derived IL-4 protein, expressed by E. coli , with N-Met labeled tag. The total length of IL-4 Protein, Canine is 108 a.a., with molecular weight of 12-14 kDa.
  • HY-P7216
    IL-3 Protein, Canine

    rCaIL-3; Mast CELl growth factor; MCGF; Hematopoietic growth factor

    		 Canine E. coli
    IL-3 Protein, Canine is a hemopoietic growth factor involved in the survival, proliferation and differentiation of multipotent hemopoietic cells.
  • HY-P73188
    IL-2 Protein, Canine (C147S)

    Interleukin-2; T-CELl growth factor; TCGF

    		 Canine E. coli
    IL-2 Protein, produced by activated T-cells, NK cells, and helper T-cells, is crucial for immune response and tolerance. It binds to receptor complexes, activating signaling pathways. IL-2 Protein acts as a growth factor, enhances NK-cell activity, promotes B-cell proliferation, and regulates regulatory T-cells. It also participates in differentiating effector T-cell subsets and memory CD8-positive T-cells. IL-2 Protein, Canine (C147S) is the recombinant canine-derived IL-2 protein, expressed by E. coli , with tag free and C147S mutation.
  • HY-P73341
    PD-1 Protein, Canine (HEK293, Fc)

    CD279; PDCD1; Programmed CELl death 1; SLEB2

    		 Canine HEK293
    Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. PDCD1 plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but PDCD1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Canine (HEK293, Fc) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P74324
    CD2 Protein, Canine (HEK293, His)

    T-CELl surface antigen CD2; LFA-2; CD2; SRBC

    		 Canine HEK293
    CD2 Protein is a cell surface glycoprotein that is expressed on the surface of T cells, NK cells, thymus cells and dendritic cells. The CD2 Protein mediates the adhesion of T cells to various cell types and triggers T cell responses through interactions with lymphocyte function-related antigens CD58 (LFA-3) and CD48/BCM1. CD2 Protein, Canine (HEK293, His) is the recombinant canine-derived CD2 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD2 Protein, Canine (HEK293, His) is 183 a.a., with molecular weight of 35-45 kDa.
  • HY-P74325
    CD2 Protein, Canine (HEK293, Fc)

    T-CELl surface antigen CD2; LFA-2; CD2; SRBC

    		 Canine HEK293
    CD2 Protein is a cell surface glycoprotein that is expressed on the surface of T cells, NK cells, thymus cells and dendritic cells. The CD2 Protein mediates the adhesion of T cells to various cell types and triggers T cell responses through interactions with lymphocyte function-related antigens CD58 (LFA-3) and CD48/BCM1. CD2 Protein, Canine (HEK293, Fc) is the recombinant canine-derived CD2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD2 Protein, Canine (HEK293, Fc) is 183 a.a., with molecular weight of ~64.4 kDa.
  • HY-P73342
    PD-1 Protein, Canine (HEK293, His)

    CD279; hPD-1; PDCD1; Programmed CELl death 1; SLEB2

    		 Canine HEK293
    The Angiopoietin-1 Protein is a secreted glycoprotein that is a key ligand in the vascular tyrosine kinase signaling pathway. ANGPT1 stimulates angiogenesis by activating PTK2/FAK and downstream kinase MAPK1/ERK2 and MAPK3/ERK1 signaling pathways. ANGPT1 affects the proliferation, migration and differentiation of skeletal muscle cells. PD-1 Protein, Canine (HEK293, His) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Canine (HEK293, His) is 145 a.a., with molecular weight of ~34.88 and 65.02 kDa.
  • HY-P73717
    PD-L1 Protein, Canine (HEK293, Fc)

    Programmed CELl death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    		 Canine HEK293
    PD-L1 Protein, Canine (HEK293, Fc) is a trans-membrane protein that is considered to be a co-inhibitory factor of the immune response. The amino acid sequence of PD-L1 is encoded by 7 exons, which form a protein of ~40 kDa. PD-L1 is a type I transmembrane protein, is part of the immunoglobulin (Ig) superfamily and is composed of IgV-like and IgC-like extracellular domains, a hydrophobic transmembrane domain and a short cytoplasmic tail composed of 30 amino acids. PD-L1 can combine with PD-1 to reduce the proliferation of PD-1 positive cells, inhibit their cytokine secretion and induce apoptosis. PD-L1 also plays an important role in various malignancies where it can attenuate the host immune response to tumor cells. PD-L1 Protein, Canine (HEK293, Fc) is the recombinant canine-derived PD-L1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-L1 Protein, Canine (HEK293, Fc) is 218 a.a., with molecular weight of ~70-80 & 140-160 kDa, respectively.
  • HY-P75169
    GDNF Protein, Canine (HEK293, Fc)

    Glial CELl line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3

    		 Canine HEK293
    Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a N-Terminal Fc-tag. It consists of 103 amino acids (R109-I211).
  • HY-P73342A
    PD-1 Protein, Canine (HEK293, C-His)

    CD279; hPD-1; PDCD1; Programmed CELl death 1; SLEB2

    		 Canine HEK293
    The Angiopoietin-1 Protein is a secreted glycoprotein that is a key ligand in the vascular tyrosine kinase signaling pathway. ANGPT1 stimulates angiogenesis by activating PTK2/FAK and downstream kinase MAPK1/ERK2 and MAPK3/ERK1 signaling pathways. ANGPT1 affects the proliferation, migration and differentiation of skeletal muscle cells. PD-1 Protein, Canine (HEK293, C-His) is the recombinant canine-derived PD-1, expressed by HEK293 , with C-6*His labeled tag. ,
  • HY-P73727
    PD-1 Protein, Canine (Biotinylated, HEK293, His-Avi)

    Programmed CELl death protein 1; PD1; CD279; PDCD1

    		 Canine HEK293
    Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. PDCD1 plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but PDCD1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Canine (Biotinylated, HEK293, His-Avi) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
  • HY-P703855
    PD-L1 Protein, Canine (218a.a, HEK293, His)

    Programmed CELl death 1 ligand 1; PD-L1; B7-H1; CD274; PDL1

    		 Canine HEK293
  • HY-P73608
    TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, His)

    Hepatitis A virus CELlular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1

    		 Canine HEK293
    TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, His) is the recombinant canine-derived TIM-1/KIM-1/HAVCR, expressed by HEK293 , with N-His labeled tag. ,
  • HY-P73609
    TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, Fc)

    Hepatitis A virus CELlular receptor 1; HAVcr-1; KIM-1; TIM-1; CD365; HAVCR1

    		 Canine HEK293
    TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, Fc) is the recombinant canine-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-mFc labeled tag. The total length of TIM-1/KIM-1/HAVCR Protein, Canine (HEK293, Fc) is 140 a.a., with molecular weight of ~41.8 kDa.

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