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β-Estradiol hemihydrate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	17β-HSD (2) ADC Linker (1) Apoptosis (7) Autophagy (4) Bacterial (4) Bcl-2 Family (2) Drug Derivative (2) Drug Metabolite (1) Endogenous Metabolite (19) Estrogen Receptor/ERR (29) GABA Receptor (2) Glycosidase (1) HBV (2) iGluR (1) Isotope-Labeled Compounds (17) Microtubule/Tubulin (4) P-glycoprotein (1) PROTAC Linkers (1) Reactive Oxygen Species (4)
By Research Areas:	Cancer (29) Endocrinology (17) Infection (1) Inflammation/Immunology (1) Metabolic Disease (6) Neurological Disease (7)

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Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148586

β-Estradiol 17-hemisuccinate	Drug Derivative	Others
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol (HY-B0141) .

HY-B0672

Estradiol valerate β-Estradiol 17-valerate	Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0708

β-Estradiol 17-acetate 1,3,5(10)-Estratriene-3,17β-diol 17-acetate	Estrogen Receptor/ERR	Endocrinology
β-Estradiol 17-acetate is a metabolite of estradiol.

HY-B0672R

Estradiol valerate (Standard) β-Estradiol 17-valerate (Standard)	Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate (Standard) is the analytical standard of Estradiol valerianate. This product is intended for research and analytical applications. Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0141

Estradiol Maximum Cited Publications 87 Publications Verification β-Estradiol; E2; 17β-Estradiol; 17β-OEstradiol	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Endocrinology Cancer
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B1192

Estradiol benzoate 10+ Cited Publications β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate	Estrogen Receptor/ERR HBV Bcl-2 Family	Neurological Disease
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .

HY-141672

17β-Estradiol sulfate sodium 1 Publications Verification 17β-Estradiol 3-sulfate sodium	GABA Receptor	Neurological Disease
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .

HY-141672S1

17β-Estradiol sulfate-d4 sodium 17β-Estradiol 3-sulfate-d₄ sodium	GABA Receptor	Neurological Disease
17β-Estradiol sulfate-d₄ (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].

HY-B0141C

Estradiol hemihydrate β-Estradiol hemihydrate; 17β-Estradiol hemihydrate; 17β-OEstradiol hemihydrate	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Neurological Disease Cancer
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B0672S1

Estradiol valerianate-d4 β-Estradiol 17-valerate-d₄	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B1192S

Estradiol benzoate-d3 β-Estradiol 3-benzoate-d₃; 17β-Estradiol 3-benzoate-d₃	Estrogen Receptor/ERR	Neurological Disease
Estradiol benzoate-d₃ is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a proagent of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

HY-141907S

17β-Estradiol-13C3	Isotope-Labeled Compounds	Others
17β-Estradiol- ¹³C₃ is the ¹³C labeled 17β-Estradiol[1].

HY-132723AS

17β-Estradiol-3-β-D-glucuronide-d3 sodium	Isotope-Labeled Compounds	Others
17β-Estradiol-3-β-D-glucuronide-d₃ (sodium) is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

HY-132723S

17β-Estradiol-3-β-D-glucuronide-d3	Isotope-Labeled Compounds	Others
17β-Estradiol-3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

HY-142279S

17β-Estradiol 17-acetate 3-β-D-glucuronide-d3	Isotope-Labeled Compounds	Others
17β-Estradiol 17-acetate 3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide[1].

HY-130046S1

16β-Hydroxy-17β-estradiol-2,4-d2	Bacterial Isotope-Labeled Compounds	Others
16β-Hydroxy-17β-estradiol-2,4-d₂ is the deuterium labeled 16β-Hydroxy-17β-estradiol-2,4[1].

HY-142798S

16-Keto 17β-Estradiol-d5 (Major)	Isotope-Labeled Compounds	Others
16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].

HY-146631S

4-Hydroxy-17β-estradiol-1,2,16,16,17-d5	Isotope-Labeled Compounds	Others
4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].

HY-133407

β-Estradiol-6-one 6-(O-carboxymethyloxime)	PROTAC Linkers	Cancer
β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-130929

β-Estradiol-6-CMO-PEG3-biotin	ADC Linker	Cancer
β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-N10403

4-Hydroxyestradiol 1 Publications Verification 4-Hydroxy-17β-Estradiol	Drug Metabolite Endogenous Metabolite	Cancer
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a K_i of 0.48 nM .

HY-B0141R

Estradiol (Standard) Maximum Cited Publications 87 Publications Verification β-Estradiol(Standard); E2(Standard); 17β-Estradiol(Standard); 17β-OEstradiol (Standard)	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Endocrinology Cancer
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-101604

Atrimustine Bestrabucil; KM2210	Drug Derivative	Cancer
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.

HY-W114419

Bisphenol C	Estrogen Receptor/ERR	Others
Bisphenol C is an ERα agonist and ERβ antagonist that inhibits 17β-estradiol .

HY-B1617

Zuclomiphene	Estrogen Receptor/ERR	Metabolic Disease
Zuclomiphene (compound 23) is a potent inhibitor of 17β-Estradiol (HY-B0141) and can inhibit the secretion of luteinizing hormone (LH) .

HY-124489

2-Hydroxyestradiol 2 Publications Verification	Endogenous Metabolite	Metabolic Disease
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity .

HY-B0672S

Estradiol valerianate-d9	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-N9134

5-O-Methylgenistein Isoprunetin	Glycosidase	Others
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast .

HY-124489S1

2-Hydroxyestradiol-d5	Endogenous Metabolite	Infection
2-Hydroxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[[1][3][4].

HY-144314

PSDalpha	Estrogen Receptor/ERR	Cancer
PSDalpha is an ERα degrader conjugating photosensitizer (PS), triphenylamine benzothiadiazole (TB) and 17β-estradiol via an acetylene bond. PSDalpha shows excellent anti-proliferation performance on MCF-7 cells. The maximum absorption wavelength of PSDalpha in the visible region is located at 465 nm .

HY-124489S

2-Hydroxyestradiol-13C6	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2-Hydroxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[1][3].

HY-128976

10β,17β-dihydroxyestra-1,4-dien-3-one DHED	Estrogen Receptor/ERR	Metabolic Disease
10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) is a brain-targeting bioprecursor proagent of the main human estrogen, 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain .

HY-125263

OP-1074	Estrogen Receptor/ERR	Cancer
OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC₅₀ values of 1.6 and 3.2 nM, respectively.

HY-129583

Lepidiline A	17β-HSD	Cancer
Lepidiline A exhibits cytotoxic activity against HL-60 cells with an IC₅₀ value of 32.3 μM. Lepidiline A targets HSD17B1 activity, increases the bioconversion efficiency of sex hormones (including the conversion of estrogen into 17β-estradiol and 4-androsten-3,7-dione into testosterone), thereby improving the reproductive capacity of fruit flies. .

HY-B1192R

Estradiol benzoate (Standard)	Estrogen Receptor/ERR HBV Bcl-2 Family	Neurological Disease
Estradiol benzoate (Standard) is the analytical standard of Estradiol benzoate. This product is intended for research and analytical applications. Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .

HY-125263B

(R)-OP-1074	Estrogen Receptor/ERR	Cancer
(R)-OP-1074 is an isomer of OP-1074 (HY-125263) and can serve as a control compound in experiments. OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC₅₀ values of 1.6 and 3.2 nM, respectively.

HY-12033

2-Methoxyestradiol 25+ Cited Publications 2-ME2; NSC-659853	Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-131404

TPBM 1 Publications Verification	Estrogen Receptor/ERR	Cancer
TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC₅₀ value of 9 μM for 17β-estradiol (E2)-ERα. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC₅₀=5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth .

HY-W587691

16-Ketoestradiol 16-keto-17β-Estradiol	Endogenous Metabolite	Endocrinology
6-Ketoestradiol is an active metabolite of the endogenous estrogen estrone .

HY-161211

HSD17B13-IN-7	17β-HSD iGluR	Metabolic Disease
HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC₅₀s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research .

HY-12033S2

2-Methoxyestradiol-d5 2-ME2-d₅; NSC-659853-d₅	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6][7].

HY-12033S

2-Methoxyestradiol-13C,d3	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-12033S1

2-Methoxyestradiol-13C6 2-ME2-¹³C₆; NSC-659853-¹³C₆	Isotope-Labeled Compounds Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite	Cancer
2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-B0141S3

Estradiol-d2 β-Estradiol-d₂; 17β-Estradiol-d₂; 17β-OEstradiol-d₂	Isotope-Labeled Compounds Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estradiol-d₂ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0141S

Estradiol-d3 β-Estradiol-d₃; 17β-Estradiol-d₃; 17β-OEstradiol-d₃	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estradiol-d₃ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.

HY-B0141S2

Estradiol-d5 β-Estradiol-d₅; 17β-Estradiol-d₅; 17β-OEstradiol-d₅	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estradiol-d₅ is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0141S1

Estradiol-d4 1 Publications Verification β-Estradiol-d₄; 17β-Estradiol-d₄; 17β-OEstradiol-d₄	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estradiol-d₄ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-123742

Estradiol 3-sulfate 17-glucuronide potassium	P-glycoprotein	Metabolic Disease
Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17-(β -D-Glucuronide) transport with a K_i of 22 μM .

HY-103454B

MPP hydrochloride 5+ Cited Publications	Estrogen Receptor/ERR Apoptosis	Endocrinology Cancer
MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP hydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP hydrochloride reverses the the positive effects of *beta-estradiol. MPP hydrochloride has mixed agonist/antagonist action on murine uterine ERalpha* in vivo .

HY-103454

MPP dihydrochloride 5+ Cited Publications	Estrogen Receptor/ERR Apoptosis	Endocrinology Cancer
MPP dihydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP dihydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP dihydrochloride reverses the positive effects of beta-estradiol. MPP dihydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0708

β-Estradiol 17-acetate 1,3,5(10)-Estratriene-3,17β-diol 17-acetate	Structural Classification Monophenols Classification of Application Fields Animals Source classification Phenols Disease Research Fields Endocrinology Steroids	Estrogen Receptor/ERR
β-Estradiol 17-acetate is a metabolite of estradiol.

HY-B0141

Estradiol Maximum Cited Publications 87 Publications Verification β-Estradiol; E2; 17β-Estradiol; 17β-OEstradiol	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Monophenols Sunscreen Disease markers Phenols Cosmetic Research Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B1192

Estradiol benzoate 10+ Cited Publications β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate	Classification of Application Fields Disease Research Fields Cancer	Estrogen Receptor/ERR HBV Bcl-2 Family
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .

HY-N10403

4-Hydroxyestradiol 1 Publications Verification 4-Hydroxy-17β-Estradiol	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields Steroids Cancer	Drug Metabolite Endogenous Metabolite
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a K_i of 0.48 nM .

HY-B0141R

Estradiol (Standard) Maximum Cited Publications 87 Publications Verification β-Estradiol(Standard); E2(Standard); 17β-Estradiol(Standard); 17β-OEstradiol (Standard)	Structural Classification Classification of Application Fields Sunscreen Source classification Disease markers Phenols Endocrine diseases Cosmetic Research Endogenous metabolite Disease Research Fields Steroids Cancer	Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-124489

2-Hydroxyestradiol 2 Publications Verification	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity .

HY-129583

Lepidiline A	Alkaloids Structural Classification other families Classification of Application Fields Other Alkaloids Source classification Plants Disease Research Fields Cancer	17β-HSD
Lepidiline A exhibits cytotoxic activity against HL-60 cells with an IC₅₀ value of 32.3 μM. Lepidiline A targets HSD17B1 activity, increases the bioconversion efficiency of sex hormones (including the conversion of estrogen into 17β-estradiol and 4-androsten-3,7-dione into testosterone), thereby improving the reproductive capacity of fruit flies. .

HY-12033

2-Methoxyestradiol 25+ Cited Publications 2-ME2; NSC-659853	Structural Classification Monophenols Classification of Application Fields Source classification Disease markers Phenols Endocrine diseases Endogenous metabolite Disease Research Fields Steroids Cancer	Microtubule/Tubulin Reactive Oxygen Species Apoptosis Autophagy Endogenous Metabolite
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .

HY-N9134

5-O-Methylgenistein Isoprunetin	Structural Classification Flavonoids Leguminosae Source classification Maackia amurensis Rupr. et Maxim. Plants Isoflavones	Glycosidase
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast .

HY-W587691

16-Ketoestradiol 16-keto-17β-Estradiol	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
6-Ketoestradiol is an active metabolite of the endogenous estrogen estrone .

Cat. No.	Product Name	Chemical Structure

HY-141672S1

17β-Estradiol sulfate-d4 sodium
17β-Estradiol sulfate-d₄ (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].

HY-B1192S

Estradiol benzoate-d3
Estradiol benzoate-d₃ is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a proagent of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

HY-132723AS

17β-Estradiol-3-β-D-glucuronide-d3 sodium
17β-Estradiol-3-β-D-glucuronide-d₃ (sodium) is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

HY-B0672S1

Estradiol valerianate-d4
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-141907S

17β-Estradiol-13C3
17β-Estradiol- ¹³C₃ is the ¹³C labeled 17β-Estradiol[1].

HY-132723S

17β-Estradiol-3-β-D-glucuronide-d3
17β-Estradiol-3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].

HY-142279S

17β-Estradiol 17-acetate 3-β-D-glucuronide-d3
17β-Estradiol 17-acetate 3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide[1].

HY-130046S1

16β-Hydroxy-17β-estradiol-2,4-d2
16β-Hydroxy-17β-estradiol-2,4-d₂ is the deuterium labeled 16β-Hydroxy-17β-estradiol-2,4[1].

HY-142798S

16-Keto 17β-Estradiol-d5 (Major)
16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].

HY-146631S

4-Hydroxy-17β-estradiol-1,2,16,16,17-d5
4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].

HY-B0672S

Estradiol valerianate-d9
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-124489S1

2-Hydroxyestradiol-d5
2-Hydroxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[[1][3][4].

HY-124489S

2-Hydroxyestradiol-13C6
2-Hydroxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[1][3].

HY-12033S2

2-Methoxyestradiol-d5

2-Methoxyestradiol-d₅ is the deuterium labeled 2-Hydroxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6][7].

HY-12033S

2-Methoxyestradiol-13C,d3

2-Methoxyestradiol- ¹³C,d₃ is the ¹³C- and deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-12033S1

2-Methoxyestradiol-13C6

2-Methoxyestradiol- ¹³C₆ is the ¹³C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].

HY-B0141S3

Estradiol-d2
Estradiol-d₂ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0141S

Estradiol-d3
Estradiol-d₃ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.

HY-B0141S2

Estradiol-d5
Estradiol-d₅ is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0141S1

Estradiol-d4 1 Publications Verification
Estradiol-d₄ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0141S6

Estradiol-d2-1
Estradiol-d₂-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3][4].

HY-B0141S4

Estradiol-13C6
Estradiol- ¹³C₆ is the ¹³C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0141S5

Estradiol-13C2
Estradiol- ¹³C₂ is the ¹³C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

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HY-P83688

	Estradiol Antibody Beta-Estradiol, 17beta-Estradiol, estrace, oEstradiol, dihydrofolliculin, progynon, dihydroxyestrin, dihydrotheelin, diogynets	ELISA	Species independent

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β-Estradiol hemihydrate

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