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AZA

" in MedChemExpress (MCE) Product Catalog:

46

Inhibitors & Agonists

4

Fluorescent Dye

1

Biochemical Assay Reagents

2

Peptides

2

Natural
Products

3

Isotope-Labeled Compounds

3

Click Chemistry

12

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116269
    AZA197

    		Ras Apoptosis PAK ERK Cancer
    AZA197 is a selective small molecule inhibitor of Cdc42.AZA197 suppresses colon cancer cell proliferation, cell migration, invasion and increases apoptosis by down-regulating the PAK1 and ERK signaling pathways in vitro. AZA197 reduces tumor growth and significantly increases mouse survival in SW620 tumor xenografts. AZA197 can be used for the study of colon cancer .
    AZA197
  • HY-D2864
    Aza-CyBz

    		Fluorescent Dye Others
    Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
    Aza-CyBz
  • HY-136383
    AZA1
    1 Publications Verification

    Rac1/Cdc42-IN-1

    		 Ras Apoptosis Cancer
    AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion .
    AZA1
  • HY-10222
    Ixabepilone
    5+ Cited Publications

    BMS-247550; AZA-epothilone B

    		 Microtubule/Tubulin Apoptosis Bacterial Cancer
    Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.
    Ixabepilone
  • HY-139015
    5-Aza-4'-thio-2'-deoxycytidine

    5-AZA-T-dCyd; NTX-301

    		 DNA Methyltransferase Cancer
    5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd) is an orally active DNA methyltransferase I (DNMT1) inhibitor. 5-Aza-4'-thio-2'-deoxycytidine, a sulfur-containing deoxy-cytidine analog, has the potential for DNA hypomethylating and has antitumor effects .
    5-Aza-4'-thio-2'-deoxycytidine
  • HY-111627
    5-Aza-7-deazaguanine
    1 Publications Verification

    		 Nucleoside Antimetabolite/Analog Cancer
    5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides .
    5-Aza-7-deazaguanine
  • HY-124844
    Azaphilone-9

    AZA-9

    		 HuR Cancer
    Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC50=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression .
    Azaphilone-9
  • HY-10222R
    Ixabepilone (Standard)

    BMS-247550 (Standard); AZA-epothilone B (Standard)

    		 Reference Standards Microtubule/Tubulin Apoptosis Bacterial Cancer
    Ixabepilone (Standard) is the analytical standard of Ixabepilone. This product is intended for research and analytical applications. Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.
    Ixabepilone (Standard)
  • HY-CE00762
    2-Aza-butyryl-CoA

    		Biochemical Assay Reagents Metabolic Disease
    2-Aza-butyryl-CoA is a coenzyme A derivative.
    2-Aza-butyryl-CoA
  • HY-18005
    4-Aza-Oleanolic acid methyl ester

    		Drug Derivative Others
    4-Aza-Oleanolic acid methyl ester is a triterpenic derivative .
    4-Aza-Oleanolic acid methyl ester
  • HY-154470
    8-Aza-2’-deoxyguanosine

    		Nucleoside Antimetabolite/Analog Cancer
    8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Aza-2’-deoxyguanosine
  • HY-152743
    8-Aza-7-deazguanosine

    		Nucleoside Antimetabolite/Analog Cancer
    8-Aza-7-deazguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Aza-7-deazguanosine
  • HY-154120
    6-Aza-2'-deoxyuridine

    		Nucleoside Antimetabolite/Analog Cancer
    6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    6-Aza-2'-deoxyuridine
  • HY-154399
    5-Aza-3’-deoxycytidine

    		Nucleoside Antimetabolite/Analog Cancer
    5-Aza-3’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Aza-3’-deoxycytidine
  • HY-D1186
    2-Aza-ε-adenosine

    2-AZA-1,N6-ethenoadenosine

    		 Fluorescent Dye Others
    2-Aza-ε-adenosine (2-Aza-1,N6-ethenoadenosine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    2-Aza-ε-adenosine
  • HY-154400
    5-Aza-3’-beta-methylcytidine

    		Nucleoside Antimetabolite/Analog Cancer
    5-Aza-3’-beta-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Aza-3’-beta-methylcytidine
  • HY-152467
    8-Aza-2’-beta-C-methylguanosine

    		Nucleoside Antimetabolite/Analog Cancer
    8-Aza-2’-beta-C-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Aza-2’-beta-C-methylguanosine
  • HY-152733
    8-Aza-7-bromo-7-deazaguanosine

    		Nucleoside Antimetabolite/Analog Cancer
    8-Aza-7-bromo-7-deazaguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Aza-7-bromo-7-deazaguanosine
  • HY-139456S
    1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d3

    		Isotope-Labeled Compounds Others
    1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d3 is the deuterium labeled 1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole .
    1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole-d3
  • HY-177020
    GS-6620 PM

    1'-Cyano-2'-C-methyl 4-AZA-7,9-dideAZA adenosine

    		 Nucleoside Antimetabolite/Analog Infection
    GS-6620 PM (Compound 2) is an analog of 2′-C-methyl 4-aza-7,9-dideaza adenosine. 2′-C-methyl 4-aza-7,9-dideaza adenosine is an inhibitor of HCV replication in cell culture. GS-6620 PM can be used in the study of hepatitis C virus (HCV) infection .
    GS-6620 PM
  • HY-152831
    2-Amino-8-aza-7-deaza-7-iodoguanosine

    		Nucleoside Antimetabolite/Analog Cancer
    2-Amino-8-aza-7-deaza-7-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2-Amino-8-aza-7-deaza-7-iodoguanosine
  • HY-154398
    5-Aza-xylo-cytidine

    		Nucleoside Antimetabolite/Analog Cancer
    5-Aza-xylo-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Aza-xylo-cytidine
  • HY-W767228
    Decitabine-15N4

    5-AZA-2'-deoxy cytidine-15N4

    		 Isotope-Labeled Compounds Others
    Decitabine- 15N4 (5-Aza-2'-deoxy cytidine- 15N4) is 15N labeled Decitabine .
    Decitabine-15N4
  • HY-151763
    Boc-L-Aza-OH (CHA)

    		ADC Linker Others
    Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Boc-L-Aza-OH (CHA)
  • HY-D1187
    2-Aza-ε-cAMP

    		Fluorescent Dye Others
    2-Aza-ε-cAMP is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    2-Aza-ε-cAMP
  • HY-D1187A
    2-Aza-ε-cAMP sodium

    		Fluorescent Dye Others
    2-Aza-ε-cAMP (sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    2-Aza-ε-cAMP sodium
  • HY-151784
    Boc-D-Aza-OH

    		ADC Linker Others
    Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Boc-D-Aza-OH
  • HY-A0004S
    Decitabine-13C5

    5-AZA-2'-deoxycytidine-13C5; 5-AZA-CdR-13C5; NSC 127716-13C5

    		 Isotope-Labeled Compounds DNA Methyltransferase Nucleoside Antimetabolite/Analog Apoptosis Cancer
    Decitabine- 13C5 (5-Aza-2'-deoxycytidine- 13C5) is 13C labeled Decitabine. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .
    Decitabine-13C5
  • HY-W419403
    Boc-D-Aza-OH (CHA)

    		ADC Linker Others
    Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Boc-D-Aza-OH (CHA)
  • HY-154359
    2’-O-Acetyl-3’,5’-bis-O-benzoyl-6-aza-xylo uridine

    		Nucleoside Antimetabolite/Analog Cancer
    2’-O-Acetyl-3’,5’-bis-O-benzoyl-6-aza-xylo uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2’-O-Acetyl-3’,5’-bis-O-benzoyl-6-aza-xylo uridine
  • HY-110044
    MNITMT

    		Others Inflammation/Immunology
    MNITMT is a more potent immunosuppressive agent without bone marrow toxicity .
    MNITMT
  • HY-P2191
    KISS1-305

    		Kisspeptin Receptor Endocrinology
    KISS1-305, the Metastin/Kisspeptin analog, is a prototype peptide and a chemical probe. KISS1-305 has suboptimal KISS1R agonistic activity, and resists plasma protease degradation .
    KISS1-305
  • HY-50071
    6-Amino-5-nitropyridin-2-one

    		Nucleoside Antimetabolite/Analog Others
    6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine .
    6-Amino-5-nitropyridin-2-one
  • HY-112205A
    RR-11a analog
    5+ Cited Publications

    		 Parasite Legumain Infection
    RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor .
    RR-11a analog
  • HY-A0004
    Decitabine
    Maximum Cited Publications
    147 Publications Verification

    5-AZA-2'-deoxycytidine; 5-AZA-CdR; NSC 127716

    		 DNA Methyltransferase Apoptosis Nucleoside Antimetabolite/Analog Cancer
    Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .
    Decitabine
  • HY-W020445
    7-(tert-Butyl) 2-methyl 3-bromo-7-azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylate

    3-Bromo-7-AZA-bicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylic acid 7-tert-butyl ester 2-methyl ester

    		 Drug Intermediate Others
    7-(tert-Butyl) 2-methyl 3-bromo-7-azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylate (3-Bromo-7-aza-bicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylic acid 7-tert-butyl ester 2-methyl ester) is a drug intermediate for synthesis of various active compounds.
    7-(tert-Butyl) 2-methyl 3-bromo-7-azabicyclo[2.2.1]hepta-2,5-diene-2,7-dicarboxylate
  • HY-P4693
    (Ser(tBu)6,Azagly10)-LHRH

    		GnRH Receptor Endocrinology
    (Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog .
    (Ser(tBu)6,Azagly10)-LHRH
  • HY-105165A
    Nortopixantrone dihydrochloride

    BBR 3438

    		 Antibiotic Cancer
    Nortopixantrone dihydrochloride (BBR 3438) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone dihydrochloride plays an important role in cacner research .
    Nortopixantrone dihydrochloride
  • HY-A0004R
    Decitabine (Standard)

    5-AZA-2'-deoxycytidine (Standard); 5-AZA-CdR (Standard); NSC 127716 (Standard)

    		 Reference Standards DNA Methyltransferase Apoptosis Nucleoside Antimetabolite/Analog Cancer
    Decitabine (Standard) is the analytical standard of Decitabine. This product is intended for research and analytical applications. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .
    Decitabine (Standard)
  • HY-105165
    Nortopixantrone

    BBR 3438 free base

    		 Antibiotic Cancer
    Nortopixantrone (BBR 3438 free base) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone plays an important role in cacner research .
    Nortopixantrone
  • HY-D1453
    Immune initiator-1

    		Biochemical Assay Reagents Cancer
    Immune initiator-1 (Compound 1a) is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .
    Immune initiator-1
  • HY-139076
    Menin-MLL inhibitor 19

    		Epigenetic Reader Domain Metabolic Disease Cancer
    Menin-MLL inhibitor 19, a potent exo-aza spiro inhibitor of menin-mll interaction, example A17, extracted from patent WO2019120209A1. Menin-MLL inhibitor 19 can be used for the reseaech of various diseases, such as cancer, myelodysplastic syndrome (MDS) and diabetes .
    Menin-MLL inhibitor 19
  • HY-13778R
    3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylic acid (Standard)

    		Reference Standards
    3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylic acid (Standard)
  • HY-W007656
    Cyclen

    		Others Others
    Cyclen is a macrocyclic tetraamine. Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates. Cyclen is employed as a structural regulator through interfacial polymerization of polyethleneimine (PEI) and trimesoyl chloride (TMC) to develop polyamide NF membrane with efficient Li +/Mg 2+ separation performance. Cyclen has specific cavity structure and exhibits selective coordination properties for Li + ions .
    Cyclen
  • HY-W007656R
    Cyclen (Standard)

    		Others Others
    Cyclen is a macrocyclic tetraamine. Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates. Cyclen is employed as a structural regulator through interfacial polymerization of polyethleneimine (PEI) and trimesoyl chloride (TMC) to develop polyamide NF membrane with efficient Li+/Mg2+ separation performance. Cyclen has specific cavity structure and exhibits selective coordination properties for Li+ ions .
    Cyclen (Standard)
  • HY-Y0549
    Diphenylacetic acid

    Diphenylmethane-α-carboxylic Acid

    		 Biochemical Assay Reagents Others
    Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .
    Diphenylacetic acid

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