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GSK983 is a broad-spectrum antiviral agent. GSK983 inhibits the replication of adenovirus-5 (Ad-5) and polyoma virus SV40. GSK983 inhibits the growth of cell lines immortalized by
EBV, HTLV1, HPV. GSK983 induces the expression of interferon-stimulated genes .
Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity .
Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA .
λ Protein phosphatase is a serine/threonine phosphatase encoded by bacteriophage Lambda. λ Protein phosphatase is activated with requirement for divalent cations, such as Mn 2+. λ Protein phosphatase is able to dephosphorylate casein, adenovirus E1A protein, and the α subunit of phosphorylase kinase
ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection .
Apoptolidin is a polyketide isolated from Nocardiopsis?bacteria . Apoptolidin is a selective mitochondrial F1FO ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells .
Strictamine (compound 2) is an alkaloid with antiviral activity. Strictamine has significant inhibitory activity against herpes simplex virus (HSV) and adenovirus (ADV), with EC50 values ??of 0.36 μg/mL and 0.28 μg/mL, respectively .
Ingavirin (Ingamine) exhibits broad spectrum antiviral activities against human respiratory viruses, such as influenza virus A (IVA), human parainfluenza virus (hPIV) and human adenovirus (AdV). Ingavirin exhibits no toxixcity to mice at the dose of 3000 mg/kg .
Oxyclozanide (Standard) is the analytical standard of Oxyclozanide. This product is intended for research and analytical applications. Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity .
1,3-Diarachidonoyl glycerol (DG(20:4/0:0/20:4)) is a compound that is being studied for its selective cell killing mechanism, and it has a selective killing effect on cells transformed by the E1A gene of adenovirus type 12. Its killing effect is attributed to lipid peroxidation, and its structural characteristics are crucial to the specificity of this cytotoxicity, which ultimately exerts cytotoxic effects by destroying the cell membrane.
FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .
Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
Ganciclovir (BW 759) hydrate, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir hydrate also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir hydrate inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir hydrate has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
Braco-19 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .
Ganciclovir (Standard) is the analytical standard of Ganciclovir. This product is intended for research and analytical applications. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
Braco-19 trihydrochloride is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .
Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA .
Apoptolidin is a polyketide isolated from Nocardiopsis?bacteria . Apoptolidin is a selective mitochondrial F1FO ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells .
Strictamine (compound 2) is an alkaloid with antiviral activity. Strictamine has significant inhibitory activity against herpes simplex virus (HSV) and adenovirus (ADV), with EC50 values ??of 0.36 μg/mL and 0.28 μg/mL, respectively .
rHuCoxsackievirus and Adenovirus receptor/CXADR, His ; Coxsackievirus and Adenovirus Receptor; CAR; hCAR; CVB3-Binding Protein; Coxsackievirus B-Adenovirus Receptor; HCVADR; CXADR; CAR
CXADR proteins are components of the epithelial apical junction complex and, as cell adhesion molecules, are critical for the integrity of tight junctions. CXADR Protein, Human (HEK293, His) is the recombinant human-derived CXADR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CXADR Protein, Human (HEK293, His) is 218 a.a., with molecular weight of ~32.0 kDa.
CXADR protein is a key component of the epithelial apical junction complex, which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML. This interaction activates γ-δ T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase. CXADR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CXADR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CXADR Protein, Mouse (HEK293, Fc) is 218 a.a., with molecular weight of 50-70 kDa.
BNIP3L, a pro-apoptotic member of the Bcl-2 family, possesses a BH3 domain and binds to Bcl-2. It directly targets mitochondria, inducing apoptotic changes like membrane potential loss and cytochrome c release. With ubiquitous expression, especially in fat and ovary, the gene suggests involvement in diverse physiological processes across multiple organs, emphasizing its potential significance. BNIP3L Protein, Human is the recombinant human-derived BNIP3L protein, expressed by E. coli , with tag free. The total length of BNIP3L Protein, Human is 186 a.a., with molecular weight of ~32-36 kDa.
CXADR protein is a key component of the epithelial apical junction complex, which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML. This interaction activates γ-δ T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase. CXADR Protein, Mouse (Biotinylated, HEK293, Avi-His) is the recombinant mouse-derived CXADR protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CXADR Protein, Mouse (Biotinylated, HEK293, Avi-His) is 218 a.a., with molecular weight of 30-40 kDa.
Adenovirus E1B19k binding protein B5; BNIP3a; BNIP3H; BNIP3L; BNIP3L protein; NIP3 like protein X; NIP3L; NIX
WB, IHC-P
Human, Mouse, Rat
BNIP3L Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 24 kDa, targeting to BNIP3L. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.
BCL2 Adenovirus E1B 19kD interacting protein 1; BNIP1; Nip1; sec20; SEC20L; Transformation-related gene 8 protein; TRG8; Vesicle transport protein SEC20
WB, IHC-P
Human, Mouse, Rat
BNIP1 Antibody (YA3329) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3329), targeting BNIP1, with a predicted molecular weight of 26 kDa (observed band size: 26 kDa). BNIP1 Antibody (YA3329) can be used for WB, IHC-P experiment in human, mouse, rat background.
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