Search Result
Results for "
Antimicrobial-IN-1
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N2544
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- HY-170312
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Bacterial
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Infection
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Antimicrobial-IN-1 (compound 17) exhibits strong antibacterial activity against S. aureus and E. coli, with the inhibition zone diameter of 18 , 16 mm/mg, respectively [1].
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- HY-121272
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- HY-W683885
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- HY-N8916
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- HY-122089
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- HY-145265
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Bacterial
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Infection
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Antimicrobial photosensitizer-1 is a promising candidate as the antimicrobial photosensitizer for combating pathogenic microorganism infections. Antimicrobial photosensitizer-1 exhibits an impressive antimicrobial efficacy in S. aureus-infected mice wounds [1].
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- HY-111405
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Bacterial
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Infection
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Antimicrobial Compound 1 is an alkylpyridinium compound, with antimicrobial activity.
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- HY-N4003
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Bacterial
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Infection
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Isobonducellin is a flavonoid product and shows antimicrobial activity .
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- HY-153722
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Bacterial
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Infection
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Dodicin is an effective disinfectant with broad antimicrobial activity .
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- HY-153722A
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Bacterial
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Infection
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Dodicin hydrochloride is an effective disinfectant with broad antimicrobial activity .
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- HY-P5577
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-
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- HY-125596
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Parasite
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Infection
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Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .
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-
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- HY-113582
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-
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- HY-N15193
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- HY-146078
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Bacterial
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Infection
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Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines [1].
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- HY-N8148
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- HY-B0343
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- HY-N1101
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-
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- HY-131718
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Bacterial
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Infection
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(1-Isothiocyanatoethyl)benzene (compound 27) is an antimicrobial agent .
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- HY-137945
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PheneticillIN sodium; α-PhenoxyethylpenicillIN sodium
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Bacterial
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Infection
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Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
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- HY-156980
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|
Bacterial
|
Infection
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Podilfen is an active fraction of Delftia strains 2189 with antimicrobial effects .
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- HY-125455
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Bacterial
|
Infection
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Ro 41-1879 is a catechol cephalosporin that has antimicrobial activity .
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- HY-123234
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- HY-122790
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Bacterial
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Infection
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2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities .
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-
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- HY-124452
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DesferrioxamINe E; NocardamIN
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Bacterial
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Others
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Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity .
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-
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- HY-N3060
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|
Bacterial
|
Infection
|
(S)-5,7-Diacetoxyflavanone is a flavanone with antimicrobial activity .
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-
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- HY-A0153A
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CefapirIN sodium
|
Bacterial
Antibiotic
|
Infection
|
Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
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- HY-A0153
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- HY-N8411
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(+)-Aromadendrene
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Bacterial
|
Infection
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Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity .
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- HY-N7747
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Others
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Infection
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Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent .
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- HY-121272AS
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- HY-N3636
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- HY-105713
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Bacterial
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Infection
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Sulochrin is a metabolite produced by Aspergillus terreus var. aureus. I. Sulochrin has antimicrobial activities .
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- HY-117685
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Bacterial
|
Infection
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Cefovecin sodium is a cephalosporin. Cefovecin sodium interferes with bacterial cell wall synthesis. Cefovecin sodium shows antimicrobial activator .
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- HY-137564
-
|
Antibiotic
|
Infection
|
Desacetylcephalothin sodium is a metabolite of Cephalothin (HY-B1275A). Desacetylcephalothin sodium exhibits a weak antimicrobial activity .
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-
-
- HY-119246
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-
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- HY-N7784
-
|
Antibiotic
Bacterial
|
Infection
|
Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities .
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- HY-N0576
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-
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- HY-139570
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-
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- HY-N9880
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-
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- HY-121272R
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-
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- HY-131102
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Bacterial
DNA/RNA Synthesis
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Infection
|
Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .
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- HY-128452
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-
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- HY-W109613
-
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Bacterial
|
Infection
|
Methyl dehydroabietate is a kind of resin acid that can be isolated from spruce bark. Methyl dehydroabietate has antimicrobial activities .
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- HY-161312
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Bacterial
Fungal
|
Infection
|
Antifungal agent 93 (compound 10) is a potent antifungal agent. Antifungal agent 93 shows antimicrobial activity .
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- HY-P2656
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hBD-4
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Bacterial
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Infection
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β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity .
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- HY-N4247
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- HY-112057
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LY267108
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Drug Metabolite
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Others
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Pseudoerythromycin A enol ether (LY267108) is a degradation product of Erythromycin. Pseudoerythromycin A enol ether has no significant antimicrobial activity .
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- HY-121295
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Bacterial
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Infection
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Roseoflavin, a natural pigment originally isolated from Streptomyces davawensis, is an antimetabolite analog of Riboflavin and flavin mononucleotide that has antimicrobial properties .
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- HY-N3947
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Bacterial
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Infection
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Glepidotin B is a dihydroflavonol compound isolated from the extracts of American licorice, Glycyrrhiza lepidota (Leguminosae). Glepidotin B is an antimicrobial agent .
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- HY-122428
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Bacterial
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Infection
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Samandarone is an alkaloid that can be isolated from the skin gland secretions of Salammedra maculosa and Leptodactylus pentadactylus, which exhibits antimicrobial activity .
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- HY-B0343R
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Antibiotic
Bacterial
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Infection
|
Sarafloxacin (Standard) is the analytical standard of Sarafloxacin. This product is intended for research and analytical applications. Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent .
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- HY-B0343S
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A-56620-d8
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Isotope-Labeled Compounds
|
Infection
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Sarafloxacin-d8 is the deuterium labeled Sarafloxacin(HY-B0343).Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent .
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- HY-137945R
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Bacterial
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Infection
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Phenethicillin (sodium) (Standard) is the analytical standard of Phenethicillin (sodium). This product is intended for research and analytical applications. Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
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- HY-B1137
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IsopropylamINoantipyrINe
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Bacterial
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Inflammation/Immunology
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Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
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- HY-N10457
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Bacterial
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Infection
Cancer
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Norstictic acid is a potent and selective allossteric transcriptional regulator. Norstictic acid shows anticancer activity. Norstictic acid shows antioxidant activity and antimicrobial activity .
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- HY-138137
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Bacterial
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Infection
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Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity .
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- HY-P0324A
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Bacterial
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Infection
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Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity .
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- HY-149294
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- HY-A0153AR
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Bacterial
Antibiotic
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Infection
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Cephapirin (sodium) (Standard) is the analytical standard of Cephapirin (sodium). This product is intended for research and analytical applications. Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
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- HY-A0153R
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Antibiotic
Bacterial
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Infection
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Cephapirin (Standard) is the analytical standard of Cephapirin. This product is intended for research and analytical applications. Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
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- HY-169191
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Bacterial
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Infection
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Quorum sensing-IN-8 (compound 5e) has anti-biofilm activity. Quorum sensing-IN-8 can be used for the study of antimicrobial resistance .
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- HY-70083
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- HY-N1203
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- HY-169154
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Bacterial
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Infection
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ChlaDUB1-IN-1 (Compound 8) is an inhibitor for Chlamydia deubiquitinase 1 (ChlaDUB1). ChlaDUB1-IN-1 can be used in antimicrobial research .
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- HY-W015820
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Bacterial
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Inflammation/Immunology
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Phthalide is a promising chemical scaffold with a potent anti-inflammatory efficacy. Phthalide can be used to synthesize a variety of phthalide derivatives including anti-inflammatory agent, antimicrobial, antioxidant .
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- HY-123025
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Fungal
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Inflammation/Immunology
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Schizozygine is an alkaloid that can be isolated from Schizozygia caffaeoides. Schizozygia caffaeoides has been used as a traditional medicine for skin disease. The leaf extracts has high antifungal and antimicrobial activity .
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- HY-N0576R
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- HY-163190
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Bacterial
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Infection
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NDM-1 inhibitor-4 (compound 27) is a NDM-1 inhibitor with Ki of 1.7 μM. NDM-1 inhibitor-4 has antimicrobial effect .
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- HY-144513
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Bacterial
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Infection
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Stigmastan-3β-ol is a sterol that can be isolated from Tinospora sinensis and Ginkgo biloba L.. Stigmastan-3β-ol has antimicrobial activity .
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- HY-131102R
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Bacterial
DNA/RNA Synthesis
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Infection
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Mequindox (Standard) is the analytical standard of Mequindox. This product is intended for research and analytical applications. Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .
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- HY-100589
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Sch 21420 sulfate
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Bacterial
Antibiotic
|
Infection
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Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance .
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- HY-149762
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Bacterial
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Infection
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IMBI (compound 32) is an antibacterial agent that inhibits quorum sensing (QS) against drug-resistant pathogens. IMBI inhibits biofilm formation of Salmonella marcescens and restores or increases its susceptibility to antimicrobial drugs .
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- HY-113627
-
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Antibiotic
Bacterial
Apoptosis
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Infection
Inflammation/Immunology
Cancer
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Undecylprodigiosin, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin shows immunosuppressive, anticancer properties and antimicrobial activities .
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- HY-113627A
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Antibiotic
Bacterial
Apoptosis
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Infection
Inflammation/Immunology
Cancer
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Undecylprodigiosin hydrochloride, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin hydrochloride can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin hydrochloride shows immunosuppressive, anticancer properties and antimicrobial activities .
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- HY-135525
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- HY-135901
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ADC Cytotoxin
Bacterial
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Cancer
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Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity .
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- HY-18061
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(Rac)-STA-21
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STAT
Bacterial
|
Infection
Cancer
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Ochromycinone ((Rac)-STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity .
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- HY-N7906
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MyricetIN 3-β-D-glucopyranoside
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Bacterial
Parasite
Antibiotic
|
Infection
Inflammation/Immunology
|
Myricetin 3-O-glucoside (Myricetin 3-β-D-glucopyranoside) is a flavonol from Tibouchina paratropica. Myricetin 3-O-glucoside exhibits anti-Leishmanial, anti-inflammatory and antimicrobial activities .
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- HY-N10528
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- HY-N4247R
-
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Bombesin Receptor
Bacterial
|
Infection
|
Kuwanon G (Standard) is the analytical standard of Kuwanon G. This product is intended for research and analytical applications. Kuwanon G is a flavonoid isolated from Morus alba, acts as a bombesin receptor antagonist, with potential antimicrobial activity .
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- HY-N9096
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Bacterial
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Neurological Disease
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Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .
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- HY-147777
-
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Bacterial
DNA/RNA Synthesis
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Infection
|
14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-2 has antimicrobial activities .
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- HY-B1137R
-
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Bacterial
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Inflammation/Immunology
|
Ramifenazone (Standard) is the analytical standard of Ramifenazone. This product is intended for research and analytical applications. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .
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- HY-B1290
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Phenylethyl alcohol; Phenethyl alcohol; Benzyl carbINol
|
Bacterial
Virus Protease
|
Infection
|
2-Phenylethanol (Phenethyl alcohol) is an aromatic alcohol with a rose-like odour. 2-Phenylethanol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. 2-Phenylethanol has antityrosinase and antimicrobial activities .
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- HY-145417
-
|
Bacterial
|
Infection
|
G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter. Transmembrane ATP-binding cassette (ABC) transporters are crucial cellular machines that move molecules small and large across membranes. G092 has the potential for the research of antimicrobial agents .
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- HY-147778
-
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Bacterial
DNA/RNA Synthesis
|
Infection
|
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase. 14α-Demethylase/DNA Gyrase-IN-1 has antimicrobial activities .
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- HY-126462
-
|
Bacterial
|
Infection
|
Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents .
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- HY-100435
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MCB-3837; DNV3837
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Bacterial
|
Infection
|
Oxaquin (MCB-3837) is a injectable proagent that is rapidly converted to the active substance MCB3681 in vivo following intravenous (i.v.) administration, active against Gram-positive bacterial species. Oxaquin (MCB-3837) itself has no antimicrobial effects .
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- HY-128525
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
Enterobactin is a bacterial siderophore that promotes iron absorption and can be used to study inflammation. Enterobactin also disrupts macrophage (MΦs) iron homeostasis and M1/M2 polarization to protect intracellular bacteria from host antimicrobial effects .
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- HY-126662
-
|
Bacterial
|
Infection
|
Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
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- HY-151918
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance .
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- HY-P10564
-
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Bacterial
|
Infection
|
Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .
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- HY-169973
-
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Beta-lactamase
Bacterial
|
Infection
|
PhoPS is the photocaged inhibitor for β-lactamase. PhoPS is activated upon light irradiation, and active β-lactamase inhibitor Sulbactam (HY-B0334) is released. PhoPS inhibits the synthesis of bacterial cell wall and the formation of E. coli biofilm, exhibits antimicrobial activity .
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- HY-19992
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Bromopyruvic acid; HexokINase II INhibitor II, 3-BP
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Hexokinase
Apoptosis
Autophagy
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Cancer
|
3-Bromopyruvate (Bromopyruvic acid) is an analogue of pyruvate and a potent hexokinase (HK)-II inhibitor with high tumor selectivity. 3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis. 3-Bromopyruvate induces autophagy by stimulating ROS formation in breast cancer cells. Antimicrobial activities .
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- HY-139324
-
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GSK-3
Amyloid-β
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Neurological Disease
Cancer
|
Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu(II)GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu(II)GTSM also decreases the abundance of Amyloid-β trimers. Cu(II)GTSM is a potential anticancer and antimicrobial agent .
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- HY-B1794
-
-
- HY-E70030
-
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Bacterial
|
Infection
|
GlcNAc 1-P uridyltransferase (CjGlmU) is a sugar nucleotidyltransferase (SNT). GlcNAc 1-P uridyltransferase (CjGlmU) utilizes UTP and GlcNAc-1-P as its natural substrates, synthesizes UDP-GlcNAc. GlcNAc 1-P uridyltransferase (CjGlmU) has the potential for the research of antimicrobial agents .
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- HY-139745
-
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Beta-lactamase
Bacterial
|
Infection
|
FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity .
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- HY-139745A
-
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Beta-lactamase
Bacterial
|
Infection
|
FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity .
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- HY-162624
-
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Bacterial
|
Infection
|
Quorum sensing-IN-5 is a RpfF-targeted quorum-sensing inhibitor. Quorum sensing-IN-5 inhibits Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) with EC50 values of 9.91 μg/mL and 7.04 μg/mL. Quorum sensing-IN-5 has antimicrobial activity .
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- HY-P10536
-
|
Bacterial
|
Infection
|
Temporin SHF is a broad-spectrum antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria and yeasts, but does not have hemolytic activity. Temporin SHF disrupts the acyl chain stacking of anionic lipid bilayers, leading to cracks and disintegration of microbial membranes. Temporin SHF can be used in the development of antimicrobial drugs .
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-
- HY-135900
-
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ADC Cytotoxin
Bacterial
|
Cancer
|
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Aniline-MPB-amino-C3-PBD is a sequence-selective DNA minor-groove binding agent. Aniline-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity .
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-
- HY-W040795
-
|
DNA/RNA Synthesis
Endogenous Metabolite
|
Infection
|
N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent .
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- HY-P10411
-
|
Bacterial
|
Infection
|
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
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- HY-P10539
-
|
Bacterial
|
Infection
|
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
|
-
- HY-B1794A
-
|
Dopamine Receptor
Histamine Receptor
Bacterial
Amyloid-β
|
Infection
Neurological Disease
|
Thiethylperazine dimaleate, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine dimaleate is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine dimaleate has anti-emetic, antipsychotic and antimicrobial effects .
|
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- HY-B1290R
-
Phenylethyl alcohol (Standard); Phenethyl alcohol (Standard); Benzyl carbINol (Standard)
|
Virus Protease
Bacterial
|
Infection
|
2-Phenylethanol (Standard) is the analytical standard of 2-Phenylethanol. This product is intended for research and analytical applications. 2-Phenylethanol (Phenethyl alcohol) is an aromatic alcohol with a rose-like odour. 2-Phenylethanol is a flavour and fragrance compound, and can be used as a preservative and anti-microbial agent. 2-Phenylethanol has antityrosinase and antimicrobial activities .
|
-
- HY-167685
-
|
Bacterial
|
Inflammation/Immunology
|
(E/Z)-Aureusidin is a flavonoid compound with antioxidant activity. (E/Z)-Aureusidin can inhibit the production of reactive oxygen species and reduce cell damage. (E/Z)-Aureusidin has anti-inflammatory effects and can reduce the expression of inflammatory factors. (E/Z)-Aureusidin has inhibitory effects on a variety of bacteria, indicating its potential antimicrobial properties .
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-
- HY-N7510
-
12-Methoxycarnosic acid
|
5 alpha Reductase
|
Infection
Cancer
|
12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity .
|
-
- HY-P10306
-
|
Bacterial
|
Infection
|
Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
|
-
- HY-P10556
-
|
Bacterial
|
Infection
|
(KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents .
|
-
- HY-144659
-
|
Beta-lactamase
Apoptosis
Bacterial
|
Infection
|
Metallo-β-lactamase-IN-5 (compound 5c) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-5 shows inhibitory activity against MBLs NDM-1 and VIM-1. Metallo-β-lactamase-IN-5 inhibits HUVECs with an IC50 of 45 μg/mL. Metallo-β-lactamase-IN-5 plus Imipenem exhibits synergistic antimicrobial activity .
|
-
- HY-W013376
-
1-(Diphenylmethyl)piperazINe; 1-BenzhydrylpiperazINe
|
Antibiotic
Bacterial
Penicillin-binding protein (PBP)
|
Infection
Cancer
|
Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents [1] .
|
-
- HY-P5057B
-
|
Fluorescent Dye
Bacterial
|
Infection
|
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
|
-
- HY-N7510R
-
|
5 alpha Reductase
|
Infection
Cancer
|
12-O-Methylcarnosic acid (Standard) is the analytical standard of 12-O-Methylcarnosic acid. This product is intended for research and analytical applications. 12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-124452
-
DesferrioxamINe E; NocardamIN
|
Chelators
|
Nocardamine (Deferrioxamine E)is an iron carrier/Iron chelator with antimicrobial activity .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1633
-
-
- HY-P0324A
-
|
Bacterial
|
Infection
|
Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity .
|
-
- HY-P5577
-
-
- HY-P2656
-
hBD-4
|
Bacterial
|
Infection
|
β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity .
|
-
- HY-P10564
-
|
Bacterial
|
Infection
|
Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .
|
-
- HY-P10536
-
|
Bacterial
|
Infection
|
Temporin SHF is a broad-spectrum antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria and yeasts, but does not have hemolytic activity. Temporin SHF disrupts the acyl chain stacking of anionic lipid bilayers, leading to cracks and disintegration of microbial membranes. Temporin SHF can be used in the development of antimicrobial drugs .
|
-
- HY-P10411
-
|
Bacterial
|
Infection
|
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance .
|
-
- HY-P10539
-
|
Bacterial
|
Infection
|
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
|
-
- HY-P10306
-
|
Bacterial
|
Infection
|
Cys-LL37 is a biomaterial with antimicrobial properties developed by covalently fixing to the surface of titanium. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective n-terminal coupling LL37, a surface peptide layer that kills bacteria on contact is formed. Cys-LL37 can be used in research to develop new antimicrobial biomaterials .
|
-
- HY-P10556
-
|
Bacterial
|
Infection
|
(KFF)3K is a cell penetrating peptide that can promote the absorption of other antibiotics by disrupting the outer membrane of bacteria. (KFF)3K can be introduced into a hydrocarbon scaffold to induce its antibacterial properties, making it an effective antimicrobial peptide. (KFF)3K can be used in the development of new antimicrobial agents .
|
-
- HY-P5057B
-
|
Fluorescent Dye
Bacterial
|
Infection
|
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-121272AS
-
|
Difloxacin-d3 (hydrochloride trihydrate) is a deuterium labeled Difloxacin. Difloxacin is an antimicrobial agent[1].
|
-
-
- HY-B0343S
-
|
Sarafloxacin-d8 is the deuterium labeled Sarafloxacin(HY-B0343).Sarafloxacin (A-56620) is a fluoroquinolone antimicrobial agent .
|
-
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